NAPLEX antibiotics 2025/2026
Complete Questions And Correct
Answers (Verified Answers)|Brand
New Version Grade A+!
MIC Correct Answer: lowest drug concentration that prevents visibile microbial
growth in 24 hours
gram (+) bacteria species Correct Answer: staph, strep, EC, clostridium, listeria
which antibiotics exhibit time-dependent killing? Correct Answer: penicillins,
cephalosporins
how can you increase the killing of a time-dependent antibiotic? Correct
Answer: dose more frequently, extend the infusion time
example of concentration-dependent antibiotic? Correct Answer:
aminoglycosides (gentamicin, tobramycin, amikacin)
what are the bacteriostatic antibiotics (protein synthesis inhibitors)? Correct
Answer: macrolides
aminoglycosides
tetracyclines
clindamycin
linezolid
quinupristin, dalfopristin
,what is the MOA of penicillins, cephalosporins, carbapenems, and
vancomycin? Correct Answer: cell wall inhibitors - bactericidal
what general ADRs are the black box warning for aminoglycosides? Correct
Answer: nephrotoxicity and neurotoxicity
what are the aminoglycosides? Correct Answer: tobramycin
gentamicin
amikacin
what type of nephrotoxicity do aminoglycosides cause? Correct Answer: ATN -
acute tubular necrosis
what weight do you use to dose aminoglycosides? Correct Answer: IBW (unless
TBW is less)
*use ABW if obese ( > 30% IBW)
what organisms are aminoglycosides mainly active against? Correct Answer:
gram (-): GNR, PA
extended interval dosing of the aminoglycosides? Correct Answer: gent/tobra:
4-7 mg/kg
amikacin: 15-20 mg/kg
*draw random level within 6-16 hours after dose
adjust body weight (ABW) formula? Correct Answer: IBW + [0.4(TBW - IBW)]
desired trough (traditional dosing) for gent/tobra? peak? Correct Answer:
trough: < 2 mcg/mL
, peak: 5-10 mcg/mL
amoxicilin brand name Correct Answer: Amoxil
what organisms do the penicillins cover? Correct Answer: mainly gram (+), some
gram (-)
which penicillin is the DOC in acute otitis media? Correct Answer: amoxicillin
which penicillin has activity against PA? Correct Answer: piperacillin
which penicillins do not require renal dosing? Correct Answer: nafcillin
oxacillin
dicloxacillin
Does Amoxil suspension need to be refrigerated? Correct Answer: no - stable for
14 days at room temperature
how do you need to take Pen VK? Correct Answer: on an empty stomach
what IV fluid is ampicillin only compatible with? Correct Answer: NS
what are the main penicillin drug interactions? Correct Answer: probenacid,
allopurinol - increased penicillin levels
may decrease levels of oral contraceptives
what type of killing do cephalosporins exhibit? Correct Answer: time-dependent
what are the first generation cephalosporins? Correct Answer: cefazolin and
cephalexin
Complete Questions And Correct
Answers (Verified Answers)|Brand
New Version Grade A+!
MIC Correct Answer: lowest drug concentration that prevents visibile microbial
growth in 24 hours
gram (+) bacteria species Correct Answer: staph, strep, EC, clostridium, listeria
which antibiotics exhibit time-dependent killing? Correct Answer: penicillins,
cephalosporins
how can you increase the killing of a time-dependent antibiotic? Correct
Answer: dose more frequently, extend the infusion time
example of concentration-dependent antibiotic? Correct Answer:
aminoglycosides (gentamicin, tobramycin, amikacin)
what are the bacteriostatic antibiotics (protein synthesis inhibitors)? Correct
Answer: macrolides
aminoglycosides
tetracyclines
clindamycin
linezolid
quinupristin, dalfopristin
,what is the MOA of penicillins, cephalosporins, carbapenems, and
vancomycin? Correct Answer: cell wall inhibitors - bactericidal
what general ADRs are the black box warning for aminoglycosides? Correct
Answer: nephrotoxicity and neurotoxicity
what are the aminoglycosides? Correct Answer: tobramycin
gentamicin
amikacin
what type of nephrotoxicity do aminoglycosides cause? Correct Answer: ATN -
acute tubular necrosis
what weight do you use to dose aminoglycosides? Correct Answer: IBW (unless
TBW is less)
*use ABW if obese ( > 30% IBW)
what organisms are aminoglycosides mainly active against? Correct Answer:
gram (-): GNR, PA
extended interval dosing of the aminoglycosides? Correct Answer: gent/tobra:
4-7 mg/kg
amikacin: 15-20 mg/kg
*draw random level within 6-16 hours after dose
adjust body weight (ABW) formula? Correct Answer: IBW + [0.4(TBW - IBW)]
desired trough (traditional dosing) for gent/tobra? peak? Correct Answer:
trough: < 2 mcg/mL
, peak: 5-10 mcg/mL
amoxicilin brand name Correct Answer: Amoxil
what organisms do the penicillins cover? Correct Answer: mainly gram (+), some
gram (-)
which penicillin is the DOC in acute otitis media? Correct Answer: amoxicillin
which penicillin has activity against PA? Correct Answer: piperacillin
which penicillins do not require renal dosing? Correct Answer: nafcillin
oxacillin
dicloxacillin
Does Amoxil suspension need to be refrigerated? Correct Answer: no - stable for
14 days at room temperature
how do you need to take Pen VK? Correct Answer: on an empty stomach
what IV fluid is ampicillin only compatible with? Correct Answer: NS
what are the main penicillin drug interactions? Correct Answer: probenacid,
allopurinol - increased penicillin levels
may decrease levels of oral contraceptives
what type of killing do cephalosporins exhibit? Correct Answer: time-dependent
what are the first generation cephalosporins? Correct Answer: cefazolin and
cephalexin
