y7
For Lippincott Illustrated Reviews: Pharmacology 8th Edition by
y7 y7 y7 y7 y7 y7 y7
y7 Karen Whalen||ISBN NO:10,1975170555||ISBN NO:13,978-
y7 y7 y7
1975170554||Chapter 1-48||Complete Guide A+.
y7 y7 y7
Nursestar1 Stuvia y7
Nursester 1 y7
,
,3. The nurse is teaching a patient who will be discharged home with a prescription for an
y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7
enteric- coated tablet. Which statement by the patient indicates understanding of the
y7 y7 y7 y7 y7 y7 y7 y7 y 7 y7 y7 y7
y7 teaching?
a. I may crush the tablet and put it in applesauce to improve absorption.
y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7
b. I should consume acidic foods to enhance absorption of this medication.
y7 y7 y7 y7 y7 y7 y7 y7 y7 y7
c. I should expect a delay in onset of the drugs effects after taking the tablet.
y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7
d. I should take this medication with high-fat foods to improve its
y7 y7 y7 y7 y7 y7 y7 y7 y7 y7
action. ANS: C
y7 y7 y7
Enteric-coated tablets resist disintegration in the acidic environment of the stomach and
y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7
y7 disintegrate when they reach the small intestine. There is usually some delay in onset of
y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7
y7 actions after taking these medications. Enteric-coated tablets should not be crushed or
y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7
y7 chewed, which would alter the time and location of absorption. Acidic foods will not
y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7
y7 enhance the absorption of the medication. The patient should not to eat high-fat food
y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7
y7 before ingesting an enteric-coated tablet, because high-fat foods decrease the absorption
y7 y7 y7 y7 y7 y7 y7 y7 y7 y7
y7 rate.
DIF: COGNITIVE LEVEL: Applying (Application) REF: dm 3
y7 y7 y7 y7 y7 y7 y7
y7 TOP: NURSING PROCESS: Nursing Intervention
y7 y7 y7 y7
MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
y7 y7 y7 y7 y7 y7 y7
4. A patient who is newly diagnosed with type 1 diabetes mellitus asks why insulin must
y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7
y7 be given by subcutaneous injection instead of by mouth. The nurse will explain that this is
y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7
because
y7
a. absorption is diminished by the first-pass effects in the liver.
y7 y7 y7 y7 y7 y7 y7 y7 y7
b. absorption is faster when insulin is given subcutaneously.
y7 y7 y7 y7 y7 y7 y7
c. digestive enzymes in the gastrointestinal tract prevent absorption.
y7 y7 y7 y7 y7 y7 y7
d. the oral form is less predictable with more adverse
y7 y7 y7 y7 y7 y7 y7 y7
y7 effects. ANS: C y7 y7
Insulin, growth hormones, and other protein-based drugs are destroyed in the small intestine
y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7
y7 by digestive enzymes and must be given parenterally. Because insulin is destroyed by
y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7
y7 digestive enzymes, it would not make it to the liver for metabolism with a first-pass effect.
y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7
Subcutaneous tissue has fewer blood vessels, so absorption is slower in such tissue.
y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7
y7 Insulin is given subcutaneously because it is desirable to have it absorb slowly.
y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7 y7
DIF: COGNITIVE LEVEL: Understanding (Comprehension) REF: dm 3
y7 y7 y7 y7 y7 y7 y7
y7 TOP: NURSING PROCESS: Nursing Intervention: Patient Teaching
y7 y7 y7 y7 y7 y7
Page y 7 2 y 7 of y 7 507
, MSC: NCLEX: Physiological Integrity: Pharmacological and Parenteral Therapies
y7 y7 y7 y7 y7 y7 y7
Page y 7 3 y 7 of y 7 507