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Summary Pathogenesis of the Radicular Cyst

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5 pages
2025/2026 Written for academic year
Institution
University Of The West-Indies
Course
DENT 5401
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Understand the detailed pathogenesis of the radicular cyst in a step by step graphic. It includes microscopic detail of the cellular changes that occur in cyst formation. In this pdf all detailed steps of the formation of the radicular cyst- the most common dental cyst are included. Additionally the mechanisms of cyst are growth are outlined. This topic is a high yield topic for all dental students who are now being introduced to oral pathology. With Oodnto notes, the information is accompanied by beautiful hand drawn illustrations which can appeal to the visual learner.

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PATHOPHYSIOLOGY OF THE
RADICULAR CYST

A TOOTH IS SUBJECTED TO CARIES/TRAUMA

THE BACTERIA FROM THE CARIES CAUSES
IRREVERSIBLE PULPITIS. IF LEFT UNTREATED, THE
TOOTH GOES NECROTIC.




BACTERIA WITH ENDOTOXIN




BACTERIA SPREADS DOWN THE
ROOT CANAL AND REACHES THE
PERIAPICAL BONE TO FORM A
GRANULOMA

BACTERIA AND THEIR TOXINS EXIT THE ROOT
CANAL SYSTEM THROUGH THE APICAL
FORAMEN INTO THE SURROUNDING BONE. THIS
CAUSES AN INFLAMMATORY RESPONSE
CAUSING MIGRATION OF PLASMA CELLS &
MACROPHAGES TO THE AREA FORMING A
GRANULOMA ( <10MM DIAMETER)




ALVEOLAR BONE

PLASMA CELLS & MACROPHAGES

, PATHOPHYSIOLOGY OF THE
RADICULAR CYST



CELL RESTS OF MALASSEZ ARE STIMULATED

PERSISTENCE OF INFECTION IN THE PERIAPICAL ZONE
STIMULATES CELL RESTS PF MALASSEZ IN THE PDL VIA
INTERLEUKIN 1 AND INTERLEUKIN 6. THESE CELLS PROLIFERATE
AND BEGIN THE FOUNDATION OF THE RADICULAR CYST LINING




CELL RESTS OF MALASSEZ
PROLIFERATE


THE PERIAPICAL GRANULOMA
PERSISTS

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Uploaded on
October 27, 2025
Number of pages
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Written in
2025/2026
Type
Summary
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  • dentistry
  • cyst
  • dental
  • pathology
  • oral pathology
  • odonotgenic
  • pathogenesis
  • cells
  • microbiology
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  • dds
  • dental topic
  • medicine
  • tooth
  • teeth
  • enucleation
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  • digital
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