NSG 830 Exam 1 Mod 1 exam with answers

NSG 830 Exam 1 Mod 1 exam with answers
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What are the three primary reasons for drug monitoring? -
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CORRECT ANSWERS ✔✔1. Determining therapeutic dosage
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2. Evaluating medication adequacy
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3. Identifying adverse effects
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Pharmacodynamics - CORRECT ANSWERS ✔✔The process by |\ |\ |\ |\ |\ |\ |\


which a medication works on the body.
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Pharmacokinetics - CORRECT ANSWERS ✔✔the study of drug |\ |\ |\ |\ |\ |\ |\ |\


movement throughout the body |\ |\ |\




What are the four processes of pharmacokinetics? - CORRECT
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ANSWERS ✔✔absorption, distribution, metabolism, excretion
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(ADME)


Absorption - CORRECT ANSWERS ✔✔the drug's movement from
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its site of administration into the blood.
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Factors that affect drug absorption - CORRECT ANSWERS ✔✔rate
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of dissolution, surface area, blood flow, lipid solubility, pH
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partitioning

, Distribution - CORRECT ANSWERS ✔✔the drug's movement from |\ |\ |\ |\ |\ |\ |\ |\


the blood to the interstitial space of tissues and from there into
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cells.


What determines drug distribution? - CORRECT ANSWERS ✔✔1.
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Blood flow to tissues |\ |\ |\




2. Ability of drug to move out of capillaries
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3. Ability of drug to move into cells
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Which two pathologic conditions have low regional blood flow
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that can affect drug therapy? - CORRECT ANSWERS ✔✔abscesses
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and tumors
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What drugs may cross the BBB? - CORRECT ANSWERS ✔✔Only
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drugs that are lipid soluble or have a transport system
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How do drugs cross the placenta? - CORRECT ANSWERS
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✔✔Simple diffusion (aka passive transfer) |\ |\ |\ |\




protein binding - CORRECT ANSWERS ✔✔the attachment of a
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drug molecule to a plasma or tissue protein, effectively making
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the drug inactive but also keeping it within the body.
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What is the most important protein in which drugs bind? -
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CORRECT ANSWERS ✔✔Albumin. Because of its size, it is too
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large to leave the bloodstream.
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