NR-566: Advanced Pharmacology for Care of the
Family Midterm Exam - Chamberlain University
2025/2026 | Questions and Correct Answers |
Latest Version | Verified Solution 100%
Which non-amphetamines are FDA approved for weight loss that have lower abuse risk?
Phentermine and Diethylpropion
How does Phentermine and Diethylpropion promote weight loss?
-Promote weight loss by decreasing appetite
-They are central nervous system (CNS) stimulants that suppress appetite by increasing the availability
of norepinephrine at receptors in the brain
What is the maximum recommended duration of use for non-amphetamines?
3 months or less
What drug schedule are Phentermine and Diethylpropion under?
Schedule IV
What labs should be monitored with Phentermine and Diethylpropion? What condition should we
screen for?
-baseline CMP (watch electrolytes and creatinine)
-screen for depression
Phentermine adverse effects
-increase HR and BP
-dry mouth and constipation
What is role of topiramate in weight loss?
Increases satiety
What are some Phentermine/topiramate contraindications for use?
not approved in children and contraindicated with severe hepatic impairment
How should we educate patient to take Phentermine/topiramate to avoid insomnia?
given before 1600
,What are some high-risk patient conditions that we should use Phentermine/topiramate with
caution?
hex drug abuse, glaucoma, pregnant, HTN, hyperthyroidism
Phentermine/topiramate adverse effects
insomnia, nervousness, anxiety, depression, blurred vision
Which of the following would be a contraindication to prescribing phentermine/topiramate? Select all
that apply.
A) Glaucoma
B) Hypothyroidism
C) Hypertension
D) Hyperthyroidism
E) Vitamin D Deficiency
F) A, B, E
ANSWER: A,C,D
Orlistat is a lipase inhibitor that acts on the _________ and reduces absorption of fat by 30%.
GI tract
Take multivitamin ___hours before/after to supplement fat-soluble vitamins that may not be
absorbed well when taking Orlistat.
2
Orlistat is OTC as 60 mg TID with meals. Not approved in children <____.
12
Orlistat results in the least amount of weight loss of all. How much?
2-3% body weight (7 lbs in year)
Orlistat adverse effects
Fecal incontinence, oily rectal leakage, flatus, abdominal cramps. liver damage (light-colored stools, dark
urine, fatigue, jaundice, anorexia)
When is Orlistat contraindicated?
In those with malabsorption syndrome or cholestasis
What vitamin deficiency are we concerned about when taking Orlistat...especially if the patient is on
coumadin?
Monitor Coumadin as Vitamin K deficiency may occur and intensify effect of Coumadin.
A patient with a BMI of 27 would be considered:
, overweight
Lorcaserin adverse effects
headache, URI, back pain, hypoglycemia (in DM), blood dyscrasias, cognitive impairment, psychiatric
disorders, priapism, pulmonary hypertension, and valvular heart disease
Lorcaserin MOA
Reduces waist circumference, fasting glucose, insulin, total cholesterol, LDL, triglycerides
When is Lorcaserin contraindicated?
CrCl <30
-Not approved in children
Lorcaserin drug interactions
-MAOI inhibitors, SSRIs, SNRIs, St. Johns wart, and triptans
-Increased risk for serotonin syndrome
Naltrexone and Bupropion black box warning
increased risk for suicidal ideation and suicide attempts in children, adolescents, and young adults
Do not take Naltrexone and Bupropion within ___weeks of taking a _____.
-two
-MAOI
Due to Naltrexone and Bupropion antagonist effects, it can reduce effects of what?
opioids
Naltrexone and Bupropion contraindications
HTN, seizure disorders, eating disorders, alcohol or drug withdrawal
Liraglutide MOA
-promotes weight loss by slowing gastric emptying
-increases satiety
-Not approved children.
When taking Liraglutide, it is not unusual for baseline HR to increase ______bpm
10-20
-monitor for tachycardia
When taking Liraglutide, monitor for ________ in patients with diabetes
hypoglycemia
Baseline labs for Liraglutide
Family Midterm Exam - Chamberlain University
2025/2026 | Questions and Correct Answers |
Latest Version | Verified Solution 100%
Which non-amphetamines are FDA approved for weight loss that have lower abuse risk?
Phentermine and Diethylpropion
How does Phentermine and Diethylpropion promote weight loss?
-Promote weight loss by decreasing appetite
-They are central nervous system (CNS) stimulants that suppress appetite by increasing the availability
of norepinephrine at receptors in the brain
What is the maximum recommended duration of use for non-amphetamines?
3 months or less
What drug schedule are Phentermine and Diethylpropion under?
Schedule IV
What labs should be monitored with Phentermine and Diethylpropion? What condition should we
screen for?
-baseline CMP (watch electrolytes and creatinine)
-screen for depression
Phentermine adverse effects
-increase HR and BP
-dry mouth and constipation
What is role of topiramate in weight loss?
Increases satiety
What are some Phentermine/topiramate contraindications for use?
not approved in children and contraindicated with severe hepatic impairment
How should we educate patient to take Phentermine/topiramate to avoid insomnia?
given before 1600
,What are some high-risk patient conditions that we should use Phentermine/topiramate with
caution?
hex drug abuse, glaucoma, pregnant, HTN, hyperthyroidism
Phentermine/topiramate adverse effects
insomnia, nervousness, anxiety, depression, blurred vision
Which of the following would be a contraindication to prescribing phentermine/topiramate? Select all
that apply.
A) Glaucoma
B) Hypothyroidism
C) Hypertension
D) Hyperthyroidism
E) Vitamin D Deficiency
F) A, B, E
ANSWER: A,C,D
Orlistat is a lipase inhibitor that acts on the _________ and reduces absorption of fat by 30%.
GI tract
Take multivitamin ___hours before/after to supplement fat-soluble vitamins that may not be
absorbed well when taking Orlistat.
2
Orlistat is OTC as 60 mg TID with meals. Not approved in children <____.
12
Orlistat results in the least amount of weight loss of all. How much?
2-3% body weight (7 lbs in year)
Orlistat adverse effects
Fecal incontinence, oily rectal leakage, flatus, abdominal cramps. liver damage (light-colored stools, dark
urine, fatigue, jaundice, anorexia)
When is Orlistat contraindicated?
In those with malabsorption syndrome or cholestasis
What vitamin deficiency are we concerned about when taking Orlistat...especially if the patient is on
coumadin?
Monitor Coumadin as Vitamin K deficiency may occur and intensify effect of Coumadin.
A patient with a BMI of 27 would be considered:
, overweight
Lorcaserin adverse effects
headache, URI, back pain, hypoglycemia (in DM), blood dyscrasias, cognitive impairment, psychiatric
disorders, priapism, pulmonary hypertension, and valvular heart disease
Lorcaserin MOA
Reduces waist circumference, fasting glucose, insulin, total cholesterol, LDL, triglycerides
When is Lorcaserin contraindicated?
CrCl <30
-Not approved in children
Lorcaserin drug interactions
-MAOI inhibitors, SSRIs, SNRIs, St. Johns wart, and triptans
-Increased risk for serotonin syndrome
Naltrexone and Bupropion black box warning
increased risk for suicidal ideation and suicide attempts in children, adolescents, and young adults
Do not take Naltrexone and Bupropion within ___weeks of taking a _____.
-two
-MAOI
Due to Naltrexone and Bupropion antagonist effects, it can reduce effects of what?
opioids
Naltrexone and Bupropion contraindications
HTN, seizure disorders, eating disorders, alcohol or drug withdrawal
Liraglutide MOA
-promotes weight loss by slowing gastric emptying
-increases satiety
-Not approved children.
When taking Liraglutide, it is not unusual for baseline HR to increase ______bpm
10-20
-monitor for tachycardia
When taking Liraglutide, monitor for ________ in patients with diabetes
hypoglycemia
Baseline labs for Liraglutide
