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Pathophysiology: The Biologic Basis for Disease in Adults and Children (8th Edition) – Kathryn L. McCance & Sue E. Huether | Complete Test Bank with Accurate Answers and Rationales

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This document is the full test bank for Pathophysiology: The Biologic Basis for Disease in Adults and Children (8th Edition) by Kathryn L. McCance and Sue E. Huether. It includes multiple-choice and multiple-response questions with verified answers and rationales for chapters 1 through 50. Topics cover cellular biology, genetics, immunity, hormonal regulation, cardiovascular, renal, pulmonary, digestive, and neurologic systems, as well as pediatric and cancer pathophysiology. Ideal for nursing, medical, and allied health students preparing for exams.

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Pathophysiology: The Biologic Basis for Disease
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Pathophysiology: The Biologic Basis for Disease

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Uploaded on
October 8, 2025
Number of pages
616
Written in
2025/2026
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TEST BANK Pathophysiology: The Biologic
Basis for Disease in Adults and Children 8th
Edition by Kathryn L. McCance, Sue E. Huether
ACCURATE ANSWERS WITH RATIONALES|
CHAPTERS 1-50
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1

, Table of Contents
Chapter 01: Cellular Biology

Chapter 02: Altered Cellular and Tissue Biology: Environmental Agents

Chapter 03: The Cellular Environment: Fluids and Electrolytes, Acids and Bases

Chapter 04: Genes and Genetic Diseases

Chapter 05: Genes, Environment-Lifestyle, and Common Diseases

Chapter 06: Epigenetics and Disease

Chapter 07: Innate Immunity: Inflammation and Wound Healing

Chapter 08: Adaptive Immunity

Chapter 09: Alterations in Immunity and Inflammation

Chapter 10: Infection

Chapter 11: Stress and Disease
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Chapter 12: Cancer Biology

Chapter 13: Cancer Epidemiology
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Chapter 14: Cancer in Children
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Chapter 15: Structure and Function of the Neurologic System

Chapter 16: Pain, Temperature Regulation, Sleep, and Sensory Function
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Chapter 17: Alterations in Cognitive Systems, Cerebral Hemodynamics, and Motor Function

Chapter 18: Disorders of the Central and Peripheral Nervous Systems and the Neuromuscular Junction

Chapter 19: Neurobiology of Schizophrenia, Mood Disorders, and Anxiety Disorders

Chapter 20: Alterations of Neurologic Function in Children

Chapter 21: Mechanisms of Hormonal Regulation

Chapter 22: Alterations of Hormonal Regulation

Chapter 23: Obesity and Disorders of Nutrition

Chapter 24: Structure and Function of the Reproductive Systems

Chapter 25: Alterations of the Female Reproductive System

Chapter 26: Alterations of the Male Reproductive System

Chapter 27: Sexually Transmitted Infections


2

,Chapter 28: Structure and Function of the Hematologic System

Chapter 29: Alterations of Erythrocytes, Platelets, and Hemostatic Function

Chapter 30: Alterations of Leukocyte and Lymphoid Function

Chapter 31: Alterations of Hematologic Function in Children

Chapter 32: Structure and Function of the Cardiovascular and Lymphatic Systems

Chapter 33: Alterations of Cardiovascular Function

Chapter 34: Alterations of Cardiovascular Function in Children

Chapter 35: Structure and Function of the Pulmonary System

Chapter 36: Alterations of Pulmonary Function

Chapter 37: Alterations of Pulmonary Function in Children

Chapter 38: Structure and Function of the Renal and Urologic Systems

Chapter 39: Alterations of Renal and Urinary Tract Function
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Chapter 40: Alterations of Renal and Urinary Tract Function in Children

Chapter 41: Structure and Function of the Digestive System
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Chapter 42: Alterations of Digestive Function

Chapter 43: Alterations of Digestive Function in Children
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Chapter 44: Structure and Function of the Musculoskeletal System
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Chapter 45: Alterations of Musculoskeletal Function

Chapter 46: Alterations of Musculoskeletal Function in Children

Chapter 47: Structure, Function, and Disorders of the Integument

Chapter 48: Alterations of the Integument in Children

Chapter 49: Shock, Multiple Organ Dysfunction Syndrome, and Burns in Adults

Chapter 50: Shock, Multiple Organ Dysfunction Syndrome, and Burns in Children




3

, Chapter 01: Cellular Biology
MULTIPLE CHOICE
1. Which statement best describes the cellular function of metabolic absorption?

a. Cells can produce proteins.

b. Cells can secrete digestive enzymes.

c. Cells can take in and use nutrients.

d. Cells can synthesize fats.

RIGHT ANSWER: C

In metabolic absorption, all cells take in and use nutrients and other substances from their surroundings.
The remaining options are not inclusive in their descriptions of cellular metabolic absorption.

PTS: 1 DIF: Cognitive Level: Remembering



2. Where is most of a cell’s genetic information, including RNA and DNA, contained?
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a. Mitochondria
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b. Ribosome

c. Nucleolus
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d. Lysosome

RIGHT ANSWER: C
c

The nucleus contains the nucleolus, a small dense structure composed largely of RNA, most of the
cellular DNA, and the DNA-binding proteins, such as the histones, which regulate its activity. The
mitochondria are responsible for cellular respiration and energy production.

Ribosomes’ chief function is to provide sites for cellular protein synthesis. Lysosomes function as the
intracellular digestive system.

PTS: 1 DIF: Cognitive Level: Remembering



3. Which component of the cell produces hydrogen peroxide (H2O2) by using oxygen to remove
hydrogen atoms from specific substrates in an oxidative reaction?

a. Lysosomes

b. Peroxisomes

c. Ribosomes

d. Endosome

4

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