USMLE Step 1 Rapid Review
Study online at https://quizlet.com/_3ek56
1. Abdominal pain, ascites, he- Budd-Chiari syndrome
patomegaly, (also high D dimer, CHF
without JVD)
2. Achilles tendon xanthoma Familial hypercholesterolemia
3. Adrenal hemorrhage, hypotension, Waterhouse-Friderichsen syndrome (meningo-
DIC coccemia)
4. Arachnodactyly, lens dislocation, aor- Marfan's (fibrillin defect)
tic dissection, hyperflexible joints
5. Athlete with polycythemia Erythropoietin injection
6. Back pain, fever, night sweats, weight Pott's (TB to the vertebrae)
loss
7. Bilateral hilar adenopathy, uveitis Sarcoid
8. Blue sclera Osteogenesis imperfecta
9. Bluish line on gingiva Burton's line - lead poisoning
10. Bone pain, bone enlargement, arthri- Paget's
tis, (also increased hat size, fracture,
increased alk phos)
11. Bounding pulses, diastolic hear mur- Aortic regurg
mur, head bobbing
12. Café-au-lait spots, Lisch nodules NF (1 = optic glimoas and pheo, 2 = acoustic
Schwannomas)
13. Café-au-lait spots, polyostotic fibrous McCune-Albright syndome (G protein problem)
dysplasia, precocious puberty
, USMLE Step 1 Rapid Review
Study online at https://quizlet.com/_3ek56
14. Calf pseudohypertrophy Duchenne's muscular dystrophy
15. Cherry-red spot on macula Tay-Sachs, Niemann-Pick, central retinal artery
occlusion
16. Chest pain, pericardial effusion/fric- Dressler's (autoimmune post-MI)
tion rub, persistent fever following MI
17. Child uses arms to stand up from Gower's sign (Duchenne's)
squat
18. Child with fever develops red rash on Slapped cheek - B19
face that spreads to body
19. Chorea, dementia, caudate degenera- Huntington's
tion
20. Chronic exercise intolerance with McArdle's (muscle phosphorylase deficiency)
myalgia, fatigue, painful cramps
21. Cold intolerance Hypothyroidism
22. Conjugate lateral gaze palsy, horizon- Internuclear ophthalmoplegia (MS or stroke)
tal diplopia
23. Continuous machinery heart murmur PDA
24. Cutaneous/dermal edema due to CT Myxedema
expansion
25. Dark purple skin / mouth nodules Kaposi's sarcoma
26. Deep, labored breathing / hyperventi- Kussmaul breathing, DKA
lation
, USMLE Step 1 Rapid Review
Study online at https://quizlet.com/_3ek56
27. Dermatitis, dementia, diarrhea Pellagra (B3 / niacin deficiency)
28. Dilated cardiomyopathy, edema, Wet beriberi (B1 / thiamine deficiency)
polyneuropathy
29. Dog or cat bite resulting in infection Pasteurella multocida (local cellulitis)
30. Dry eyes, dry mouth, arthritis Sjogren's syndrome
31. Dysphagia (esophageal webs), glossi- Plummer-Vinson syndrome
tis (smooth tongue), iron deficiency
anemia
32. Elastic skin, hypermobility of joints Ehler-Danlos (type III collagen)
33. Enlarged. hard left supraclavicular VIrchow's node (abdominal met)
node
34. Erythroderma, lymphadenopathy, he- Sezary syndrome (cutaneous T cell lymphoma)
patosplenomegaly, atypical T cells
35. Facial muscle spasm upon tapping Chvostek's sign (hypocalcemia)
36. Fat, female, fertile, forty Gallstones
37. Fever, chills, headache, myalgia follow- Jarisch-Herxheimer reaction (lysis of spirochetes
ing antibiotic treatment for syphillis results in toxin release)
38. Fever, cough, conjunctivitis, coryza, dif- Measles
fuse rash, Koplick spots
39. Fever, night sweats, weight loss B symptoms or TB
40. Fibrous plaques in soft tissue of penis Peyronie's disease
Study online at https://quizlet.com/_3ek56
1. Abdominal pain, ascites, he- Budd-Chiari syndrome
patomegaly, (also high D dimer, CHF
without JVD)
2. Achilles tendon xanthoma Familial hypercholesterolemia
3. Adrenal hemorrhage, hypotension, Waterhouse-Friderichsen syndrome (meningo-
DIC coccemia)
4. Arachnodactyly, lens dislocation, aor- Marfan's (fibrillin defect)
tic dissection, hyperflexible joints
5. Athlete with polycythemia Erythropoietin injection
6. Back pain, fever, night sweats, weight Pott's (TB to the vertebrae)
loss
7. Bilateral hilar adenopathy, uveitis Sarcoid
8. Blue sclera Osteogenesis imperfecta
9. Bluish line on gingiva Burton's line - lead poisoning
10. Bone pain, bone enlargement, arthri- Paget's
tis, (also increased hat size, fracture,
increased alk phos)
11. Bounding pulses, diastolic hear mur- Aortic regurg
mur, head bobbing
12. Café-au-lait spots, Lisch nodules NF (1 = optic glimoas and pheo, 2 = acoustic
Schwannomas)
13. Café-au-lait spots, polyostotic fibrous McCune-Albright syndome (G protein problem)
dysplasia, precocious puberty
, USMLE Step 1 Rapid Review
Study online at https://quizlet.com/_3ek56
14. Calf pseudohypertrophy Duchenne's muscular dystrophy
15. Cherry-red spot on macula Tay-Sachs, Niemann-Pick, central retinal artery
occlusion
16. Chest pain, pericardial effusion/fric- Dressler's (autoimmune post-MI)
tion rub, persistent fever following MI
17. Child uses arms to stand up from Gower's sign (Duchenne's)
squat
18. Child with fever develops red rash on Slapped cheek - B19
face that spreads to body
19. Chorea, dementia, caudate degenera- Huntington's
tion
20. Chronic exercise intolerance with McArdle's (muscle phosphorylase deficiency)
myalgia, fatigue, painful cramps
21. Cold intolerance Hypothyroidism
22. Conjugate lateral gaze palsy, horizon- Internuclear ophthalmoplegia (MS or stroke)
tal diplopia
23. Continuous machinery heart murmur PDA
24. Cutaneous/dermal edema due to CT Myxedema
expansion
25. Dark purple skin / mouth nodules Kaposi's sarcoma
26. Deep, labored breathing / hyperventi- Kussmaul breathing, DKA
lation
, USMLE Step 1 Rapid Review
Study online at https://quizlet.com/_3ek56
27. Dermatitis, dementia, diarrhea Pellagra (B3 / niacin deficiency)
28. Dilated cardiomyopathy, edema, Wet beriberi (B1 / thiamine deficiency)
polyneuropathy
29. Dog or cat bite resulting in infection Pasteurella multocida (local cellulitis)
30. Dry eyes, dry mouth, arthritis Sjogren's syndrome
31. Dysphagia (esophageal webs), glossi- Plummer-Vinson syndrome
tis (smooth tongue), iron deficiency
anemia
32. Elastic skin, hypermobility of joints Ehler-Danlos (type III collagen)
33. Enlarged. hard left supraclavicular VIrchow's node (abdominal met)
node
34. Erythroderma, lymphadenopathy, he- Sezary syndrome (cutaneous T cell lymphoma)
patosplenomegaly, atypical T cells
35. Facial muscle spasm upon tapping Chvostek's sign (hypocalcemia)
36. Fat, female, fertile, forty Gallstones
37. Fever, chills, headache, myalgia follow- Jarisch-Herxheimer reaction (lysis of spirochetes
ing antibiotic treatment for syphillis results in toxin release)
38. Fever, cough, conjunctivitis, coryza, dif- Measles
fuse rash, Koplick spots
39. Fever, night sweats, weight loss B symptoms or TB
40. Fibrous plaques in soft tissue of penis Peyronie's disease
