Test Bank for Abrams’ Clinical Drug Therapy: Rationales for Nursing Practice, 13th Edition (Frandsen, 2025), Chapter 1-61 | All Chapters

Test Bank For Abrams’ Clinical Drug Therapy R
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ationales for Nursing Practice 13th Edition (Vers ion
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2024/2025) Geralyn Frandsen
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Chapter 1, The Foundation of Pharmacology: Quality and Safety
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1. A woman diagnosed with obsessive–
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compulsive disorder has been prescribed oral paroxetine hydrochloride. What is
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tthe expected effect for this prescription?
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A. Curative effect on symptoms t t t




B. Systemic effect on symptoms t t t




C. Local effect on symptoms t t t




D. Parenteral effect on symptoms t t t




ANS: B t t




Rationale: Drugs that produce systemic effects are taken into the body, circulated through
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t the bloodstream to their sites of action in various body tissues, and eventually eliminated
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t from the body. Curative agents are given to cure a disease process. In this case,
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t paroxeti ne hydrochloride will control the symptoms but not cure the disorder. Drugs with
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tlocal eff ects, such as sunscreen and local anesthetics, act mainly at the site of application.
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Paroxet ine hydrochloride is not administered parenterally. Parenteral agents are
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administered sub cutaneously, intramuscularly, or intravenously.
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PTS: 1 REF: p. 3, Introduction
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NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
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es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety KEY:
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t Integrated Process: Nursing Process t t t




BLM: Cognitive Level: Understandt t t t NOT: Multiple Choice t t t




2. A client has been prescribed an antibiotic. This medication is a naturally occurring
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tsubstance that has been cheG
mRicAalDlyEm
SoBdOifOieSd.TW
.hCaOt Mi s another name for this type o
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f medication?
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A. Synthetic drug t




B. Semisynthetic drug t




C. Biotechnology drug t




D. Prototype drug t




ANS: B t t




Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances
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tthat have been chemically modified. Synthetic drugs are more standardized in their chemic
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al characteristics, more consistent in their effects, and less likely to produce allergic react
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ions. Biotechnology drugs involve manipulating DNA and RNA and recombining genes i nto
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hybrid molecules that can be inserted into living organisms. Prototype drugs are the f irst
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drug of a particular group to be developed.
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PTS: 1 REF: p. 3, Drug Sources
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NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
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es TOP:
t t Chapter: 1: The Foundation of Pharmacology: Quality and Safety KEY:
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t Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand
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3. Which classification applies to morphine?
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A. Central nervous system depressant
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B. Central nervous system stimulant
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C. Anti-inflammatory
D. Antihypertensive

ANS: A t t




Rationale: Drugs are classified according to their effects on particular body systems, their
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ttherapeutic uses, and their chemical characteristics. Morphine is classified as a central ne
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trvous system depressant and will produce this effect in the client. A central nervous syste
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t m stimulant increases attention and raises mood. An anti-
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inflammatory agent decreases inflammation at the site of tissue or joint inflammation. An
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antihypertensive agent reduces blood pressure.
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PTS: 1 REF:
p. 3, Drug Classifications and Prototypes OBJ:
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NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapi
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tes TOP: t Chapter: 1: The Foundation of Pharmacology: Quality and Safety KEY:
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t Integrated Process: Nursing Process t t t




BLM: Cognitive Level: Remember
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4. A client is administered amoxicillin. The generic name of this medication belongs to whi ch
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tdrug group? t
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A. Selective serotonin reuptake inhibitors
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B. Diuretics
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C. Penicillins
D. ACE inhibitors t




ANS: C t t




Rationale: The generic namGeRoAfD
ten
E SinBdOicOatSesTth. C
eOdrug group (e.g., drugs with generic nam
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tes ending in ―cillin‖ are penicillins). Selective serotonin reuptake inhibitors are
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t medicatio
ns that have antidepressant effects; SSRI is a broad classification, not a generic name. Diur
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tetics are medications that increase urine output; diuretic is a broad classification, not a ge
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tneric name. ACE inhibitor is the broad classification for the angiotensin receptor blockers,
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tnot the generic name.
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PTS: 1 REF: p. 3, Drug Names
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