NR 567
NR 567 Advanced Pharm Final Exam
Study Set Questions with Correct
Verified Answers (Latest 2025/2026)
1. What are the direct thrombin inhibitor meds?: Hirudin/Lepirudin (found in
leech saliva)
Bivalirudin
Argatroban
2. Action of direct thrombin inhibitors?
(Hirudin/Lepirudin (found in leech saliva)
Bivalirudin
Argatroban): reaches and inactivates fibrin bound thrombin
3. Indications for use of direct thrombin inhibitors?
(Hirudin/Lepirudin (found in leech saliva)
Bivalirudin
Argatroban): Prevention in surgery
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4. What are the fibrinolytic meds?: Tissue plasminogen
activators (t-PA) Reteplase
Tenecteplase
5. Actions of fibrinolytic meds?
(Tissue plasminogen activators (t-PA)
Reteplase
Tenecteplase): Rapidly lyse thrombi by catalyzing the formation of plasmin
from plasminogen.
6. Indications for use of fibrinolytic meds?
(Tissue plasminogen activators (t-PA)
Reteplase
Tenecteplase): PE
DVT
thrombophlebitis
acute ischemic stroke (within 3 hours of symptom onset)
7. What are the antiplatelet meds?: Aspirin
, 3
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Clopidogrel/Plavix
8. Actions of asprin?: inhibits synthesis of thromboxane
9. Indications for asprin (antiplatelet)?: secondary prevention of vascular
events
10. Indications for Clopidogrel/plavix (antiplatelet)?: thrombosis
prevention recurrent TIA
NSTEMI
MI
Stroke
11. Actions for Clopidogrel/plavix (antiplatelet)?: Reduce platelet
aggregation by inhibiting the ADP pathway of platelets.
12. Anticoagulant considerations: CHADS-VASC
Congestive HF
HTN
Age
DM
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Stroke hx
VASCular disease
Sex
13. What is starlings law?: Link between the initial length of myocardial
fibers and the force generated by contraction.
Ventricular output increases as preload (end-diastolic pressure) increase.
14. Medications that increase preload: Fluid
Blood
Volume expanders
15. Medications that decrease preload: Nitrates (Nitroglycerin)
Ace inhibitors (Lisinopril)
ARB (Losartan)
Aldosteron Blockers
16. Medications that increase afterload: Levophed
Dopamine
Epineprhine