RAU’s Respiratory Care Pharmacology
xx xx xx
9TH EDITION xx
BY GARDENHIRE
xx
TESTBANK
,Description
Test Bank for Rau’s Respiratory Care Pharmacology 9th Edition Gardenhire
ss s s ss s s s s s s s s ss s s
Test Bank for Rau’s Respiratory Care Pharmacology, 9th Edition, Gardenhire, ISBN-10:
ss ss ss ss ss ss ss ss ss ss
0323299687, ISBN-13: 9780323299688
s s s s s s
Table of Contents s s s s
Unit I: Basic Concepts and Principles in Pharmacology
ss ss s s s s s s s s s s
1. s s Introduction to Respiratory Care Pharmacology s s s s ss s s
2. s s Principles of Drug Action s s s s ss
3. s s Administration of Aerosolized Agents s s s s s s
4. s s Calculating Drug Doses ss s s
5. ss The Central and Peripheral Nervous Systems
ss s s s s s s s s
Unit II: Drugs Used to Treat the Respiratory System
ss s s s s s s s s s s s s s s
6. Adrenergic (Sympathomimetic) Bronchodilators
ss s s s s
7. Anticholinergic (Parasympatholytic) Bronchodilators
ss ss s s
8. Xanthines
s s
9. Mucus-Controlling Drug Therapy
s s s s s s
10. Surfactant Agents
ss s s
11. Corticosteriods in Respiratory Care
s s s s s s ss
12. Nonsteroidal Antiasthma Agents
s s s s s s
13. Aerosolized Antiinfective Agents
s s s s s s
14. Antimicrobial Agents
s s s s
15. Cold and Cough Agents
s s s s s s s s
16. Selected Agents of Pulmonary Value
s s s s s s s s ss
17. Neonatal and Pediatric Aerosolized Drug Therapy
s s s s s s s s s s s s
Unit III: Critical Care, Cardiovascular, and Polysomnography Agents
ss ss s s s s s s s s s s
18. ss Skeletal Muscle Relaxants (Neuromuscular Blocking Agents)
s s s s s s s s ss
19. s s Diuretic Agents s s
20. s s Drugs Affecting the Central Nervous System
s s ss s s s s s s
21. ss Vasopressors, Inotropes, and Antiarrythmic Agents s s s s ss s s
22. ss Drugs Affecting Circulation: Antihypertensives, Antianginals, Antithrombotics
s s ss s s s s s s
23. s s Sleep and Sleep Pharmacology s s s s s s
,Chapter 01: Introduction to Respiratory Care Pharmacology
ss ss ss ss s s ss
ss Gardenhire: Rau’s Respiratory Care Pharmacology, 9th Edition
ss ss ss ss ss ss
MULTIPLE CHOICE s s
1. What is the name of the receptor sites that are located in the peripheral vasculature,
ss ss ss s s s s s s s s ss s s s s ss ss s s s s
the heart, bronchial muscle, and bronchial blood vessels?
s s s s ss s s s s s s s s s s
a. Beta 2 receptors s s c. Alpha receptors
s s ss
b. Gamma receptors d. Beta 1 receptors
ss s s s s
ANS: C s s
Alpha receptors are located in the peripheral vasculature, the heart, bronchial muscle, and
ss ss ss ss ss ss s s s s s s ss s s ss
bronchial blood vessels.
ss s s s s
PTS: 1
2. Which receptor site results in tachycardia, an increased potential for arrhythmias, and an
ss s s ss ss ss ss ss ss ss ss ss ss
increased cardiac output?
s s s s s s
a. Beta 1 receptor ss c. Alpha receptor
s s ss
b. Beta 2 receptor ss d.s s Delta receptor s s
ANS: A s s
Stimulation of the beta-1 receptors results in tachycardia, an increased potential for
s s s s s s s s s s s s s s s s s s s s s s
arrhythmias, and an increased cardiac output. In administering drugs to the pulmonary
s s ss s s s s s s s s s s s s s s s s s s s s
system, stimulation of the beta-1 sites is not desired. However, most respiratory
ss s s s s ss s s s s s s s s s s s s s s s s
pharmacologic agents have some
s s s s s s s s
beta-1 stimulatory s s
ss effect. PTS: ss 1
3. Stimulation of the beta 2 receptors causes s s s s s s s s s s s s s s
a. peripheral vasoconstriction and mild bronchoconstriction in the lungs.
ss ss ss ss ss ss ss
b. tachycardia, an increased potential for arrhythmias, and an increased cardiac output.
ss ss ss ss ss ss ss ss ss ss
c. bronchodilation.
d. peripheral vasodilation, bradycardia, and decreased cardiac output.
ss ss ss ss ss ss
ANS: C s s
Stimulation of the beta-2 receptors in the lungs causes bronchodilation.
ss ss s s s s ss ss s s ss s s
PTS: 1
4. Acetylcholine stimulates s s s s
a. the Vagus nerve. ss ss
b. the adrenergic receptors.
ss ss
c. the sympathetic nervous system.
ss ss ss
d. the cholinergic receptors.
ss ss
ANS: D s s
Acetylcholine stimulates the cholinergic receptors. ss ss ss ss
PTS: 1
5. What immunoglobulin antibody sensitizes the mast cell?
ss ss ss s s s s s s
a. Leukotrienes c. Histamine
, b. IgE d. Prostaglandins
ANS: B s s
The IgE (reagin) antibodies sensitize the mast cell. Repeated exposure to the antigen causes the
s s ss ss s s ss s s s s s s ss ss s s s s ss s s
degranulation of the mast cell.
ss s s s s s s s s
PTS: 1
6. Which of the following is caused by histamine release from the mast cells?
ss s s s s ss s s ss ss s s s s ss s s s s
I. Bronchodilation
II. Increased bronchial gland secretion ss ss ss
III. Increased amount of mucus present in the airways ss s s s s s s s s ss s s
a. I and II only s s c. III only
s s s s s s
b. II and III only s s d. I, II, IIIs s s s s s s s
ANS: B s s
Histamine is also a potent bronchoconstrictor. In addition to its bronchoconstrictive activity, histamine
ss ss ss ss ss ss ss ss ss ss ss s s
II) increases bronchial gland secretion, causing III) an increase in the amount of
ss s s s s ss ss ss s s s s ss ss ss s s
mucus present in the airways. Histamine may also have an effect on vascular
s s ss s s s s s s s s s s s s s s s s s s s s s s
permeability similar to the effect of- SRS-A.
s s s s ss s s s s s s s s
PTS: 1
7. A sympathomimetic drug would cause
ss s s s s s s s s
a. bronchodilation. c. Histamine release. ss
b. bronchoconstriction. d. Vagus nerve stimulation. s s s s
ANS: A s s
A sympathomimetic drug would cause bronchodilation. Sympathomimetic agents are the drugs most
ss ss ss ss ss ss ss ss ss ss ss
commonly used to reverse bronchospasm.
s s s s s s s s s s
PTS: 1
8. Stimulation of the sympathetic nervous system causes s s s s s s s s s s ss s s
a. vascular permeability. c. bronchodilation. ss
b. decreased blood pressure. d. bronchoconstriction. ss s s
ANS: C s s
Sympathetic nervous system stimulation causes bronchodilation. ss ss ss ss s s
PTS: 1
9. Which of the following would NOT cause a bronchospasm or bronchoconstriction?
ss s s s s ss s s ss ss s s ss s s
a. Leukotrienes c. Histamine
b. Beta 1 receptors d. Prostaglandins
s s s s
ANS: B s s
Beta-1 receptors would not cause a bronchospasm or bronchoconstriction.
s s s s s s s s s s s s s s s s
Leukotrienes are one of many chemical mediators released by the mast cells.
s s s s ss ss s s s s s s s s s s s s s s s s
Leukotrienes cause a direct, strong bronchoconstriction. Histamine is also a potent
s s s s s s s s s s ss s s s s s s s s s s
bronchoconstrictor. Prostaglandins cause a strong bronchospasm, especially in
s s s s s s s s s s s s s s s s
asthmatic patients.
s s s s
PTS: 1