TEST BANK For Psychopharmacology: Drugs, the Brain, and Behavior, 4th Edition By Meyer Nursing, Verified Chapters 1 - 20, Complete Newest Version

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Chapter 1: Principles of Pharmacology
vb vb vb vb




MultiplevbChoice

1. vb
refer(s)vbtovbspecificvbmolecularvbchangesvbthatvboccurvbwhenvbavbdrugvbbindsvbtovbavbparti
cularvbtargetvbsitevborvbreceptor,vbwhile
arevbthevbresultingvbwidespreadvbalterationsvbinvbfunction.
a. Drugvbaction;vbtherapeuticvbeffects
b. Sidevbeffects;vbdrugvbeffects
c. Therapeuticvbeffects;vbsidevbeffects
d. Drugvbaction;vbdrugvbeffects
Answer:vbd
TextbookvbReference:vbPharmacology:vbThevbSciencevbofvbDrugvbAction

2. Aftervbdrugvbadministrationvbhasvboccurred,vbthevbamountvbofvbdrugvbinvbthevbbloodvbthatvbi
svbfreevbtovbbindvbatvbspecificvbtargetvbsitesvbisvbreferredvbtovbas
a. thevbtherapeuticvbdose.
b. first-passvbeffects.
c. bioavailability.
d. ED50.
Answer:vbc
TextbookvbReference:vbPharmacokineticvbFactorsvbDeterminingvbDrugvbAction

3. Thevbspecificvbmolecularvbchangesvbthatvboccurvbwhenvbavbdrugvbbindsvbtovbavbparticularvbta
rgetvbsitevborvbreceptorvbarevbreferredvbtovbas
a. drugvbeffects.
b. drugvbaction.
c. sidevbeffects.
d. placebovbeffects.
Answer:vbb
TextbookvbReference:vbPharmacology:vbThevbSciencevbofvbDrugvbAction

4. Whichvbofvbthevbfollowingvbisvbnotvbavbpossiblevbexplanationvbforvbplacebovbeffects?
a. Pavlovianvbconditioning
b. Geneticvbvariation
c. Drugvbcompetition
d. Expectationvbofvboutcome
Answer:vbc
TextbookvbReference:vbPharmacology:vbThevbSciencevbofvbDrugvbAction

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5. The
administrationvbofvboxytocinvbhasvbbeenvbproposedvbasvbavbtreatmentvbforvbautism.
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer:vbc
TextbookvbReference:vbPharmacokineticvbFactorsvbDeterminingvbDrugvbAction

6. Whichvbfactorvbdoesvbnotvbaffectvbthevbpharmacokineticsvbofvbavbdrug?
a. Routevbofvbadministration
b. Lipidvbsolubility
c. Depotvbbinding
d. Drugvbaction
Answer:vbd
TextbookvbReference:vbPharmacokineticvbFactorsvbDeterminingvbDrugvbAction

7. First-passvbmetabolismvboccursvbwhenvbdrugsvbarevbtaken
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer:vba
TextbookvbReference:vbPharmacokineticvbFactorsvbDeterminingvbDrugvbAction

8. Thevbareavbpostremavbisvbonevbareavbinvbthevbbrainvbwherevbthe isvbnotvbcomplete.
a. cerebrospinalvbfluid
b. blood–brainvbbarrier
c. choroidvbplexus
d. phospholipidvbmembrane
Answer:vbb
TextbookvbReference:vbPharmacokineticvbFactorsvbDeterminingvbDrugvbAction

9. First-passvbmetabolismvboccursvbwithvborallyvbadministeredvbdrugsvbbecause
a. theirvbabsorptionvbisvbslowedvbbyvbfood.
b. drugsvbabsorbedvbintovbthevbbloodstreamvbfromvbthevbstomachvbgovbtovbthevblivervbonvbth
evbwayvbtovbgeneralvbcirculation.
c. drugsvbmustvbfirstvbsurvivevbthevbacidicvbenvironmentvbofvbthevbstomach.
d. salivaryvbenzymesvbinvbthevbmouthvbbeginvbthevbprocessvbofvbmetabolism.
Answer:vbb
TextbookvbReference:vbPharmacokineticvbFactorsvbDeterminingvbDrugvbAction

10. Toxicvbsubstancesvbinvbthevbbloodvbtriggervbavbvomitingvbresponsevbbyvbactivatingvbthe
a. blood–brainvbbarrier.
b. choroidvbplexus.
c. areavbpostrema.
d. medianvbeminence.


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Answer:vbc
TextbookvbReference:vbPharmacokineticvbFactorsvbDeterminingvbDrugvbAction

11. Drugsvbadministeredvb_ havevbthevbmostvbrapidvbonsetvbofvbaction.
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer:vbd
TextbookvbReference:vbPharmacokineticvbFactorsvbDeterminingvbDrugvbAction

12. Ionizationvbofvbavbdrugvbdependsvbonvbthe ofvbthevbsolutionvbandvbthe
ofvbthevbdrug.
a. pH;vbpKa
b. pKa;vbpH
c. concentration;vblipidvbsolubility
d. pH;vbconcentration
Answer:vba
TextbookvbReference:vbPharmacokineticvbFactorsvbDeterminingvbDrugvbAction

13. Thevbabsorptionvbofvbavbdrugvbdependsvbonvballvbofvbthevbfollowingvbexcept
a. lipidvbsolubility.
b. ionization.
c. bodyvbtemperature.
d. thevbconcentrationvbofvbthevbdrug.
Answer:vbc
TextbookvbReference:vbPharmacokineticvbFactorsvbDeterminingvbDrugvbAction

14. Drugsvbthatvbare shouldvbbevbavoidedvbbyvbwomenvbofvbchildbearingvbage.
a. teratogenic
b. ablevbtovbcrossvbthevbplacentalvbbarrier
c. psychoactive
d. highlyvblipid-soluble
Answer:vba
TextbookvbReference:vbPharmacokineticvbFactorsvbDeterminingvbDrugvbAction

15. Agentsvbthatvbinducevbdevelopmentalvbabnormalitiesvbinvbavbfetusvbarevbknownvbas
a. psychoactivevbdrugs.
b. illicitvbdrugs.
c. teratogens.
d. placentalvbdrugs.
Answer:vbc
TextbookvbReference:vbPharmacokineticvbFactorsvbDeterminingvbDrugvbAction

16. Depotvbbindingvbisvbsaidvbtovboccurvbwhenvbdrugs
a. bindvbtovbtheirvbtargetvbsites.



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