,Chapter 01: Drug Regulation, Actions, and Responses
x x x x x x
Workman & LaCharity: Understanding Pharmacology: Essentials for Medication Safety, 3rdEditi
x x x x x x x x x
on
MULTIPLE CHOICE B x x
ASIC CONCEPTS x
1. Which health care professional has the major responsibility for dispensing prescribeddr
x x x x x x x x x x x
ugs under the direction of a pharmacist?
x x x x x x
a. Physician
b Nurse practitioner x
.
c. Licensed nurse x
d Pharmacy technician x
.
ANS: D x
The physician and nurse practitioner have the major responsibility for prescribing drugs, not dispen
x x x x x x x x x x x x x
sing them. The licensed nurse has the primary responsibility for administering drugs, although und
x x x x x x x x x x x x x
er some circumstances a licensed nurse may dispense prescribed drugs but this isnot his or her majo
x x x x x x x x x x x x x x x x x
r responsibility in drug therapy. The pharmacy technician has the major responsibility of dispensin
x x x x x x x x x x x x x
g prescribed drugs under the direction of a licensed pharmacist.
x x x x x x x x x
DIF: Cognitive Level: Remembering x x REF: p. 3 x
2. Which term describes the effect of a drug that improves body function?
x x x x x x x x x x x
a. Side effect
x
b Intended action x
.
c. Adverse reaction x
d Idiosyncratic response x
.
ANS: B x
The purpose of drug therapy is to take a drug to prevent, reduce, or correct a health problem.Thi
x x x x x x x x x x x x x x x x x x
s response is any drug’s intended action also known as a therapeutic response.
x x x x x x x x x x x x
DIF: Cognitive Level: Remembering x x REF: p. 3 x
3. Which type of drug name is ―owned‖ by the company that manufactures it?
x x x x x x x x x x x x
a. Generic name x
b Chemical name x
, .
c. Category name x
d Trade name x
.
ANS: D x
The chemical name is a drug’s exact chemical composition. The generic name is the name assigned
x x x x x x x x x x x x x x x
to the drug by the U.S. Adopted Names Council and is not owned by anyone. The category name re
x x x x x x x x x x x x x x x x x x x
fers to the type of drug (what it does or what it is used for) and is not an actualdrug name. The trade n
x x x x x x x x x x x x x x x x x x x x x x x x
ame (brand name) is the name provided and owned by a specific drug’s manufacturer.
x x x x x x x x x x x x x
DIF: Cognitive Level: Remembering x x REF: p. 4 x
4. Which drug or drug class is a ―high alert‖ drug? x x x x x x x x x
a. Penicillin
b Insulin
.
c. NSAIDs
d Calcium
.
ANS: B x
A high alert drug is one in which harm is likely to result if given at the wrong dose, to the wrongpatie
x x x x x x x x x x x x x x x x x x x x x x
nt, or not given to the correct patient. Drugs classified as high alert drugs include potassium,narcotic
x x x x x x x x x x x x x x x x
s (opioids), insulin, cancer chemotherapy drugs, and heparin (or any drug that strongly affects blood
x x x x x x x x x x x x x x
clotting). Penicillin, NSAIDs, and calcium are not considered high alert drugs.
x x x x x x x x x x x
DIF: Cognitive Level: Remembering x x REF: p. 4 x
5. What is the term for a drug that has the same action as a naturally occurring bodyhor
x x x x x x x x x x x x x x x x x
mone or enzyme? x x
a. Agonist
b Blocking agent x
.
c. Chemical
d Duplicator
.
ANS: A x
A drug agonist is an extrinsic drug that activates the receptor sites of a cell and mimics theacti
x x x x x x x x x x x x x x x x x x
ons of naturally occurring body substances (intrinsic drugs). A blocking agent is a drug
x x x x x x x x x x x x x
, antagonist. A chemical would not necessarily be a drug at all. A duplicator is not a pharmacologicter
x x x x x x x x x x x x x x x x x
m.
DIF: Cognitive Level: Remembering x x REF: pp. 6-7 x
6. Which term describes how the body affects drug activity?
x x x x x x x x
a. Drug potency x
b Pharmacodynamics
.
c. Therapeutic effect x
d Pharmacokinetics
.
ANS: D x
The term pharmacokinetics refers to drug metabolism and how the body changes a drug. Pharmacody
x x x x x x x x x x x x x x
namics refers to how a drug works to change body function. Drug potency refers tohow strongly or to
x x x x x x x x x x x x x x x x x x x
what degree a drug exerts its effects. The therapeutic effect is closer to pharmacodynamics, meaning
x x x x x x x x x x x x x x x
how a drug works to change body function.
x x x x x x x
DIF: Cognitive Level: Remembering x x REF: p. 10 x
7. In the United States, which group is responsible for enforcing established standards fordr
x x x x x x x x x x x x x
ug manufacturing?
x
a. U.S. Pharmacopeia x
b National Institutes of Health x x x
.
c. Food and Drug Administration x x x
d Association of Pharmaceutical Manufacturers x x x
.
ANS: C x
The standards for drug manufacture are established by the U.S. Pharmacopeia. These standards are
x x x x x x x x x x x x x x
enforced by the Food and Drug Administration. Neither the National Institutes of Health northe Ass
x x x x x x x x x x x x x x x
ociation of Pharmaceutical Manufacturers has any authority to enforce drug standards.
x x x x x x x x x x
DIF: Cognitive Level: Remembering x x REF: p. 5 x
8. Which factor is a major disadvantage of the transdermal drug delivery route?
x x x x x x x x x x x
a. Only a prescriber can administer drugs by the transdermal route.
x x x x x x x x x
b Transdermal drugs must be sterile rather than clean. x x x x x x x
.
c. First pass drug loss by this route is the most extensive.
x x x x x x x x x x
d Drug absorption is dependent on adequate circulation.
x x x x x x
x x x x x x
Workman & LaCharity: Understanding Pharmacology: Essentials for Medication Safety, 3rdEditi
x x x x x x x x x
on
MULTIPLE CHOICE B x x
ASIC CONCEPTS x
1. Which health care professional has the major responsibility for dispensing prescribeddr
x x x x x x x x x x x
ugs under the direction of a pharmacist?
x x x x x x
a. Physician
b Nurse practitioner x
.
c. Licensed nurse x
d Pharmacy technician x
.
ANS: D x
The physician and nurse practitioner have the major responsibility for prescribing drugs, not dispen
x x x x x x x x x x x x x
sing them. The licensed nurse has the primary responsibility for administering drugs, although und
x x x x x x x x x x x x x
er some circumstances a licensed nurse may dispense prescribed drugs but this isnot his or her majo
x x x x x x x x x x x x x x x x x
r responsibility in drug therapy. The pharmacy technician has the major responsibility of dispensin
x x x x x x x x x x x x x
g prescribed drugs under the direction of a licensed pharmacist.
x x x x x x x x x
DIF: Cognitive Level: Remembering x x REF: p. 3 x
2. Which term describes the effect of a drug that improves body function?
x x x x x x x x x x x
a. Side effect
x
b Intended action x
.
c. Adverse reaction x
d Idiosyncratic response x
.
ANS: B x
The purpose of drug therapy is to take a drug to prevent, reduce, or correct a health problem.Thi
x x x x x x x x x x x x x x x x x x
s response is any drug’s intended action also known as a therapeutic response.
x x x x x x x x x x x x
DIF: Cognitive Level: Remembering x x REF: p. 3 x
3. Which type of drug name is ―owned‖ by the company that manufactures it?
x x x x x x x x x x x x
a. Generic name x
b Chemical name x
, .
c. Category name x
d Trade name x
.
ANS: D x
The chemical name is a drug’s exact chemical composition. The generic name is the name assigned
x x x x x x x x x x x x x x x
to the drug by the U.S. Adopted Names Council and is not owned by anyone. The category name re
x x x x x x x x x x x x x x x x x x x
fers to the type of drug (what it does or what it is used for) and is not an actualdrug name. The trade n
x x x x x x x x x x x x x x x x x x x x x x x x
ame (brand name) is the name provided and owned by a specific drug’s manufacturer.
x x x x x x x x x x x x x
DIF: Cognitive Level: Remembering x x REF: p. 4 x
4. Which drug or drug class is a ―high alert‖ drug? x x x x x x x x x
a. Penicillin
b Insulin
.
c. NSAIDs
d Calcium
.
ANS: B x
A high alert drug is one in which harm is likely to result if given at the wrong dose, to the wrongpatie
x x x x x x x x x x x x x x x x x x x x x x
nt, or not given to the correct patient. Drugs classified as high alert drugs include potassium,narcotic
x x x x x x x x x x x x x x x x
s (opioids), insulin, cancer chemotherapy drugs, and heparin (or any drug that strongly affects blood
x x x x x x x x x x x x x x
clotting). Penicillin, NSAIDs, and calcium are not considered high alert drugs.
x x x x x x x x x x x
DIF: Cognitive Level: Remembering x x REF: p. 4 x
5. What is the term for a drug that has the same action as a naturally occurring bodyhor
x x x x x x x x x x x x x x x x x
mone or enzyme? x x
a. Agonist
b Blocking agent x
.
c. Chemical
d Duplicator
.
ANS: A x
A drug agonist is an extrinsic drug that activates the receptor sites of a cell and mimics theacti
x x x x x x x x x x x x x x x x x x
ons of naturally occurring body substances (intrinsic drugs). A blocking agent is a drug
x x x x x x x x x x x x x
, antagonist. A chemical would not necessarily be a drug at all. A duplicator is not a pharmacologicter
x x x x x x x x x x x x x x x x x
m.
DIF: Cognitive Level: Remembering x x REF: pp. 6-7 x
6. Which term describes how the body affects drug activity?
x x x x x x x x
a. Drug potency x
b Pharmacodynamics
.
c. Therapeutic effect x
d Pharmacokinetics
.
ANS: D x
The term pharmacokinetics refers to drug metabolism and how the body changes a drug. Pharmacody
x x x x x x x x x x x x x x
namics refers to how a drug works to change body function. Drug potency refers tohow strongly or to
x x x x x x x x x x x x x x x x x x x
what degree a drug exerts its effects. The therapeutic effect is closer to pharmacodynamics, meaning
x x x x x x x x x x x x x x x
how a drug works to change body function.
x x x x x x x
DIF: Cognitive Level: Remembering x x REF: p. 10 x
7. In the United States, which group is responsible for enforcing established standards fordr
x x x x x x x x x x x x x
ug manufacturing?
x
a. U.S. Pharmacopeia x
b National Institutes of Health x x x
.
c. Food and Drug Administration x x x
d Association of Pharmaceutical Manufacturers x x x
.
ANS: C x
The standards for drug manufacture are established by the U.S. Pharmacopeia. These standards are
x x x x x x x x x x x x x x
enforced by the Food and Drug Administration. Neither the National Institutes of Health northe Ass
x x x x x x x x x x x x x x x
ociation of Pharmaceutical Manufacturers has any authority to enforce drug standards.
x x x x x x x x x x
DIF: Cognitive Level: Remembering x x REF: p. 5 x
8. Which factor is a major disadvantage of the transdermal drug delivery route?
x x x x x x x x x x x
a. Only a prescriber can administer drugs by the transdermal route.
x x x x x x x x x
b Transdermal drugs must be sterile rather than clean. x x x x x x x
.
c. First pass drug loss by this route is the most extensive.
x x x x x x x x x x
d Drug absorption is dependent on adequate circulation.
x x x x x x