ABRAM’S CLINICAL DRUG THERAPY RATIONALES FOR
NURSING PRACTICE 13th EDITION GERALYN FRANDSEN’S
TESTBANK/COMPLETE GUIDE 2024-2025/ALL CHAPTERS 1-61
,Chapter 1: The Foundation of Pharmacology: Quality and Safety
W W W W W W W W
1. A patient diagnosed with obsessive–compulsive disorder has been prescribed
W W W W W W W W
oral paroxetine hydrochloride. What is the expected effect for this
W W W W W W W W W W
prescription?
W
A. Curative effect on symptoms W W W
B. Systemic effect on symptoms W W W
C. Local effect on symptoms W W W
D. Parenteral effect on symptoms W W W
ACCURATE ANSWER:-B W
REASONING:->>>Pharmaceutical drug that produce systemic effects are taken into W W W W W W W W
Wthe body, circulated through the bloodstream to their sites of action in various body
W W W W W W W W W W W W W
Wtissues, and eventually eliminated from the body. Curative agents are given to cure a
W W W W W W W W W W W W W
Wdisease process. In this case, paroxetine hydrochloride will control the symptoms but
W W W W W W W W W W W
Wnot cure the disorder.
W W W
Pharmaceutical drug with local effects, such as sunscreen and local anesthetics, act
W W W W W W W W W W W
Wmainly at the site of application. Paroxetine hydrochloride is not administered
W W W W W W W W W W
Wparenterally. Parenteral agents are administered subcutaneously, intramuscularly, or
W W W W W W W
Wintravenously.
POINTS: 1 REFERENCE: p. 3, Introduction W W OBJ: 1
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and
W W W W W W W
WParenteral Therapies TOP: Chapter: 1: The Foundation of Pharmacology:
W W W W W W W
WQuality and Safety W W
KEY: Integrated Process: Nursing Process
W W W W
BLM: Cognitive Level: Understand
W NOT: Multiple Choice W W W W
2. A hospital client has been prescribed an antibiotic. This pharmaceutical drug
W W W W W W W W W W
is a naturally occurring substance that has been cheG
W W W mR
W icA
alDlyEm
SoBdOifOieSd.TW
.C
haOt Mi s W W W W W WW W W
another name for this type of pharmaceutical drug?
W W W W W W W W
A. Synthetic drug W
B. Semisynthetic drug W
C. Biotechnology drug W
D. Prototype drug W
ACCURATE ANSWER:-B W
REASONING:->>>Semisynthetic pharmaceutical drug (e.g., many antibiotics) are W W W W W W
naturally occurring substances that have been chemically modified. Synthetic
W W W W W W W W W
pharmaceutical drug are more standardized in their chemical characteristics, more
W W W W W W W W W W
consistent in their effects, and less likely to produce allergic reactions. Biotechnology
W W W W W W W W W W W W
pharmaceutical drug involve manipulating DNA and RNA and recombining genes
W W W W W W W W W W
into hybrid molecules that can be inserted into living organisms. Prototype
W W W W W W W W W W W
pharmaceutical drug are the first drug of a particular group to be developed.
W W W W W W W W W W W W W
POINTS: 1 REFERENCE: p. 3, Drug Sources OBJ: 1 W W W
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and
W W W W W W W
WParenteral Therapies TOP: Chapter: 1: The Foundation of Pharmacology:
W W W W W W W
WQuality and Safety W W
KEY: Integrated Process: Nursing Process
W W W W
BLM: Cognitive Level: Understand
W NOT: Multiple Choice W W W W
3. Which classification applies to morphine?
W W W W
A. Central nervous system depressant W W W
B. Central nervous system stimulant W W W
, C. Anti-inflammatory
D. Antihypertensive
ACCURATE ANSWER:-A W
REASONING:->>>Pharmaceutical drug are classified according to their effects on W W W W W W W W
particular body systems, their therapeutic uses, and their chemical characteristics.
W W W W W W W W W W
Morphine is classified as a central nervous system depressant and will produce this
W W W W W W W W W W W W W
effect in the hospital client. A central nervous system stimulant increases attention and
W W W W W W W W W W W W W
raises mood. An anti-inflammatory agent decreases inflammation at the site of tissue or
W W W W W W W W W W W W W
joint inflammation. An antihypertensive agent reduces blood pressure.
W W W W W W W W
POINTS: 1 REFERENCE: p. 3, Drug W W
Classifications and Prototypes OBJ:
W 1 W W W
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and
W W W W W W W
WParenteral Therapies TOP: W Chapter: 1: The Foundation of Pharmacology:
W W W W W W
WQuality and Safety W W
KEY: Integrated Process: Nursing Process
W W W W
BLM: Cognitive Level: Remember
W NOT: Multiple Choice
W W W W
4. A hospital client is administered amoxicillin. The generic name of this pharmaceutical
W W W W W W W W W W W
Wdrug belongs to which drug group?
W W W W W
A. Selective serotonin reuptake inhibitors
W W W
B. Diuretics
C. Penicillins
D. ACE inhibitors W
ACCURATE ANSWER:-C W
REASONING:->>>The generic name often indicates the drug group (e.g., pharmaceutical drug
GRADESBOOST.CO W
with generic names ending in “cillin” are penicillins). Selective serotonin reuptake
W W W W W
W W
W W
W W
W
W W
W
W
W
W W
inhibitors are pharmaceutical drugs
W W W W
that have antidepressant effects; SSRI is a broad classification, not a generic name.
W W W W W W W W W W W W
WDiuretics are pharmaceutical drugs that increase urine output; diuretic is a broad
W W W W W W W W W W W
Wclassification, not a generic name. ACE inhibitor is the broad classification for the
W W W W W W W W W W W W
Wangiotensin receptor blockers, not the generic name.
W W W W W W
POINTS: 1 REFERENCE: p. 3, Drug Names OBJ: 2 W W W
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and
W W W W W W W
WParenteral Therapies TOP: W Chapter: 1: The Foundation of Pharmacology:
W W W W W W
WQuality and Safety W W
KEY: Integrated Process: Nursing Process
W W W W
BLM: Cognitive Level: Understand
W NOT: Multiple Choice
W W W W
5. The administration of diphenhydramine is regulated by which U.S. government agency?
W W W W W W W W W W
A. Public Health Service W W
B. Federal Trade Commission W W
C. Occupational Safety and Health Administration W W W W
D. Food and W
WDrug
Administration
W
ACCURATE ANSWER:-D W
, REASONING:->>>The Food and Drug Administration approves pharmaceutical drug W W W W W W W
for over- the-counter availability, including the transfer of pharmaceutical drug from
W W W W W W W W W W W
prescription to OTC status, and may require clinical trials to determine the safety and
W W W W W W W W W W W W W W
effectiveness of OTC use. The Public Health Service is regulated by the state to
W W W W W W W W W W W W W W
maintain the health of individual citizens of the state. The Federal Trade Commission
W W W W W W W W W W W W W
regulates imports and exports throughout the nation. The Occupational Safety and
W W W W W W W W W W W
Health Administration regulates safety within the workplace.
W W W W W W W
POINTS: 1 REFERENCE: p. 4, Prescription and Nonprescription W W W W
Pharmaceutical drug OBJ: 4 W W
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and
W W W W W W W
WParenteral Therapies TOP: Chapter: 1: The Foundation of Pharmacology:
W W W W W W W
WQuality and Safety W W
KEY: Integrated Process: Nursing Process
W W W W
BLM: Cognitive Level: Understand
W NOT: Multiple Choice W W W W
6. In W the U.S., the administration of anabolic steroids is regulated by which law?
W W W W W W W W W W W
A. The Food, Drug, and Cosmetic Act of 1938
W W W W W W W
B. The Comprehensive Drug Abuse Prevention and Control Act
W W W W W W W
C. The Harrison Narcotic Act
W W W
D. The Sherley Amendment
W W
ACCURATE ANSWER:-B W
REASONING:->>>The Comprehensive Drug Abuse Prevention and Control Act W W W W W W W
regulates the manufacture and distribution of narcotics, stimulants, depressants,
W W W W W W W W W
hallucinogens, and anabolic steroids. The Food, Drug, and Cosmetic Act of 1938
W W W W W W W W W W W W
revised and broadened FDA powers and responsibilities, giving the FDA control over
W W W W W W W W W W W W
drug safety. The Harrison Narcotic Act restricted the importation, manufacture, sale,
W W W W W W W W W W W
and use of opium, cocaine, marijuana, and other pharmaceutical drug that the act d e f i Gn
W W W W W W W W W W W W W W W W W
eRd AaDs E
W naSrcBoO
tiO
csS Th.eCSOhM
. T W erley Amendment of 1912 prohibited fraudulent claims of drug
W W W W W W W W W
effectiveness.
W
POINTS: 1 REFERENCE: p. 4, Prescription and Nonprescription W W W W
Pharmaceutical drug OBJ: 3 W W
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and
W W W W W W W
WParenteral Therapies TOP: Chapter: 1: The Foundation of Pharmacology:
W W W W W W W
WQuality and Safety W W
KEY: Integrated Process: Nursing Process
W W W W
BLM: Cognitive Level: Remember
W NOT: Multiple Choice W W W W
7. A nursing attendant is responsible for maintaining an accurate count and record of
W W W W W W W W W W W W
Wthe controlled substances on the nursing division. This nursing action is regulated
W W W W W W W W W W W
Wby whichW
U.S. law or agency?
W W W
A. The Food, Drug, and Cosmetic Act of 1938
W W W W W W W
B. The Public Health Service
W W W
C. The Drug Enforcement Administration
W W W
D. The Sherley W
WAmendment ACCURATE W
WANSWER:-C
NURSING PRACTICE 13th EDITION GERALYN FRANDSEN’S
TESTBANK/COMPLETE GUIDE 2024-2025/ALL CHAPTERS 1-61
,Chapter 1: The Foundation of Pharmacology: Quality and Safety
W W W W W W W W
1. A patient diagnosed with obsessive–compulsive disorder has been prescribed
W W W W W W W W
oral paroxetine hydrochloride. What is the expected effect for this
W W W W W W W W W W
prescription?
W
A. Curative effect on symptoms W W W
B. Systemic effect on symptoms W W W
C. Local effect on symptoms W W W
D. Parenteral effect on symptoms W W W
ACCURATE ANSWER:-B W
REASONING:->>>Pharmaceutical drug that produce systemic effects are taken into W W W W W W W W
Wthe body, circulated through the bloodstream to their sites of action in various body
W W W W W W W W W W W W W
Wtissues, and eventually eliminated from the body. Curative agents are given to cure a
W W W W W W W W W W W W W
Wdisease process. In this case, paroxetine hydrochloride will control the symptoms but
W W W W W W W W W W W
Wnot cure the disorder.
W W W
Pharmaceutical drug with local effects, such as sunscreen and local anesthetics, act
W W W W W W W W W W W
Wmainly at the site of application. Paroxetine hydrochloride is not administered
W W W W W W W W W W
Wparenterally. Parenteral agents are administered subcutaneously, intramuscularly, or
W W W W W W W
Wintravenously.
POINTS: 1 REFERENCE: p. 3, Introduction W W OBJ: 1
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and
W W W W W W W
WParenteral Therapies TOP: Chapter: 1: The Foundation of Pharmacology:
W W W W W W W
WQuality and Safety W W
KEY: Integrated Process: Nursing Process
W W W W
BLM: Cognitive Level: Understand
W NOT: Multiple Choice W W W W
2. A hospital client has been prescribed an antibiotic. This pharmaceutical drug
W W W W W W W W W W
is a naturally occurring substance that has been cheG
W W W mR
W icA
alDlyEm
SoBdOifOieSd.TW
.C
haOt Mi s W W W W W WW W W
another name for this type of pharmaceutical drug?
W W W W W W W W
A. Synthetic drug W
B. Semisynthetic drug W
C. Biotechnology drug W
D. Prototype drug W
ACCURATE ANSWER:-B W
REASONING:->>>Semisynthetic pharmaceutical drug (e.g., many antibiotics) are W W W W W W
naturally occurring substances that have been chemically modified. Synthetic
W W W W W W W W W
pharmaceutical drug are more standardized in their chemical characteristics, more
W W W W W W W W W W
consistent in their effects, and less likely to produce allergic reactions. Biotechnology
W W W W W W W W W W W W
pharmaceutical drug involve manipulating DNA and RNA and recombining genes
W W W W W W W W W W
into hybrid molecules that can be inserted into living organisms. Prototype
W W W W W W W W W W W
pharmaceutical drug are the first drug of a particular group to be developed.
W W W W W W W W W W W W W
POINTS: 1 REFERENCE: p. 3, Drug Sources OBJ: 1 W W W
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and
W W W W W W W
WParenteral Therapies TOP: Chapter: 1: The Foundation of Pharmacology:
W W W W W W W
WQuality and Safety W W
KEY: Integrated Process: Nursing Process
W W W W
BLM: Cognitive Level: Understand
W NOT: Multiple Choice W W W W
3. Which classification applies to morphine?
W W W W
A. Central nervous system depressant W W W
B. Central nervous system stimulant W W W
, C. Anti-inflammatory
D. Antihypertensive
ACCURATE ANSWER:-A W
REASONING:->>>Pharmaceutical drug are classified according to their effects on W W W W W W W W
particular body systems, their therapeutic uses, and their chemical characteristics.
W W W W W W W W W W
Morphine is classified as a central nervous system depressant and will produce this
W W W W W W W W W W W W W
effect in the hospital client. A central nervous system stimulant increases attention and
W W W W W W W W W W W W W
raises mood. An anti-inflammatory agent decreases inflammation at the site of tissue or
W W W W W W W W W W W W W
joint inflammation. An antihypertensive agent reduces blood pressure.
W W W W W W W W
POINTS: 1 REFERENCE: p. 3, Drug W W
Classifications and Prototypes OBJ:
W 1 W W W
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and
W W W W W W W
WParenteral Therapies TOP: W Chapter: 1: The Foundation of Pharmacology:
W W W W W W
WQuality and Safety W W
KEY: Integrated Process: Nursing Process
W W W W
BLM: Cognitive Level: Remember
W NOT: Multiple Choice
W W W W
4. A hospital client is administered amoxicillin. The generic name of this pharmaceutical
W W W W W W W W W W W
Wdrug belongs to which drug group?
W W W W W
A. Selective serotonin reuptake inhibitors
W W W
B. Diuretics
C. Penicillins
D. ACE inhibitors W
ACCURATE ANSWER:-C W
REASONING:->>>The generic name often indicates the drug group (e.g., pharmaceutical drug
GRADESBOOST.CO W
with generic names ending in “cillin” are penicillins). Selective serotonin reuptake
W W W W W
W W
W W
W W
W
W W
W
W
W
W W
inhibitors are pharmaceutical drugs
W W W W
that have antidepressant effects; SSRI is a broad classification, not a generic name.
W W W W W W W W W W W W
WDiuretics are pharmaceutical drugs that increase urine output; diuretic is a broad
W W W W W W W W W W W
Wclassification, not a generic name. ACE inhibitor is the broad classification for the
W W W W W W W W W W W W
Wangiotensin receptor blockers, not the generic name.
W W W W W W
POINTS: 1 REFERENCE: p. 3, Drug Names OBJ: 2 W W W
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and
W W W W W W W
WParenteral Therapies TOP: W Chapter: 1: The Foundation of Pharmacology:
W W W W W W
WQuality and Safety W W
KEY: Integrated Process: Nursing Process
W W W W
BLM: Cognitive Level: Understand
W NOT: Multiple Choice
W W W W
5. The administration of diphenhydramine is regulated by which U.S. government agency?
W W W W W W W W W W
A. Public Health Service W W
B. Federal Trade Commission W W
C. Occupational Safety and Health Administration W W W W
D. Food and W
WDrug
Administration
W
ACCURATE ANSWER:-D W
, REASONING:->>>The Food and Drug Administration approves pharmaceutical drug W W W W W W W
for over- the-counter availability, including the transfer of pharmaceutical drug from
W W W W W W W W W W W
prescription to OTC status, and may require clinical trials to determine the safety and
W W W W W W W W W W W W W W
effectiveness of OTC use. The Public Health Service is regulated by the state to
W W W W W W W W W W W W W W
maintain the health of individual citizens of the state. The Federal Trade Commission
W W W W W W W W W W W W W
regulates imports and exports throughout the nation. The Occupational Safety and
W W W W W W W W W W W
Health Administration regulates safety within the workplace.
W W W W W W W
POINTS: 1 REFERENCE: p. 4, Prescription and Nonprescription W W W W
Pharmaceutical drug OBJ: 4 W W
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and
W W W W W W W
WParenteral Therapies TOP: Chapter: 1: The Foundation of Pharmacology:
W W W W W W W
WQuality and Safety W W
KEY: Integrated Process: Nursing Process
W W W W
BLM: Cognitive Level: Understand
W NOT: Multiple Choice W W W W
6. In W the U.S., the administration of anabolic steroids is regulated by which law?
W W W W W W W W W W W
A. The Food, Drug, and Cosmetic Act of 1938
W W W W W W W
B. The Comprehensive Drug Abuse Prevention and Control Act
W W W W W W W
C. The Harrison Narcotic Act
W W W
D. The Sherley Amendment
W W
ACCURATE ANSWER:-B W
REASONING:->>>The Comprehensive Drug Abuse Prevention and Control Act W W W W W W W
regulates the manufacture and distribution of narcotics, stimulants, depressants,
W W W W W W W W W
hallucinogens, and anabolic steroids. The Food, Drug, and Cosmetic Act of 1938
W W W W W W W W W W W W
revised and broadened FDA powers and responsibilities, giving the FDA control over
W W W W W W W W W W W W
drug safety. The Harrison Narcotic Act restricted the importation, manufacture, sale,
W W W W W W W W W W W
and use of opium, cocaine, marijuana, and other pharmaceutical drug that the act d e f i Gn
W W W W W W W W W W W W W W W W W
eRd AaDs E
W naSrcBoO
tiO
csS Th.eCSOhM
. T W erley Amendment of 1912 prohibited fraudulent claims of drug
W W W W W W W W W
effectiveness.
W
POINTS: 1 REFERENCE: p. 4, Prescription and Nonprescription W W W W
Pharmaceutical drug OBJ: 3 W W
NAT: Hospital client Needs: Physiological Integrity: Pharmacological and
W W W W W W W
WParenteral Therapies TOP: Chapter: 1: The Foundation of Pharmacology:
W W W W W W W
WQuality and Safety W W
KEY: Integrated Process: Nursing Process
W W W W
BLM: Cognitive Level: Remember
W NOT: Multiple Choice W W W W
7. A nursing attendant is responsible for maintaining an accurate count and record of
W W W W W W W W W W W W
Wthe controlled substances on the nursing division. This nursing action is regulated
W W W W W W W W W W W
Wby whichW
U.S. law or agency?
W W W
A. The Food, Drug, and Cosmetic Act of 1938
W W W W W W W
B. The Public Health Service
W W W
C. The Drug Enforcement Administration
W W W
D. The Sherley W
WAmendment ACCURATE W
WANSWER:-C
