NR 565 Advanced Pharmacology Week
1 Quiz Exam Actual Questions &
Answers
1. An older adult client who is hospitalized reports an inability to sleep at
night. The client is given a hypnotic medication at 2200. The next morning
the client is drowsy and wants to sleep instead of eating breakfast. The
nurse is aware that this effect is most likely due to
A. reduced hepatic function.
B. reduced cardiac function.
C. delayed toxic effect.
D. first-pass effect.
Answer A. Reduces hepatic function
Drugs are metabolized in the liver. Elderly patients are more likely to
have reduced liver function that prolongs the half-live of the
medications. As a result, the drug effect will last longer. This elderly
patient took sleeping pill the night before, and the drug effect extended
to the next morning due to the reduced liver function as evidence by
drowsiness.
2.It is expected that the nurse will question the health care provider if a
drug with a t(1/2) of a >24 hour drug is ordered to be given more than how
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15
, often.
A. Once daily
B. Every other day
C. Twice weekly
D. Once weekly
Answer A. Once daily
t(1/2) is half live. If the half life of a drug is 24 hours it should be only
given once daily. If the half life is 6 hours, it should only be given every
6 hours and so on...
3.The nurse notices that one of the client's drugs has a low therapeutic
index. What is the most important nursing implication of this?
A. A wide margin of safety
B. A narrow margin of safety
C. Measured 1 hour after administration
D. Measured 10 minutes after administration
Answer B. A narrow margin of safety.
Therapeutic index refers to the level at which a drug is more helpful
than harmful. If there is a low therapeutic index, then there is a narrow
margin of safety.
4.Which of the following nurse actions should be most appropriate for
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15
1 Quiz Exam Actual Questions &
Answers
1. An older adult client who is hospitalized reports an inability to sleep at
night. The client is given a hypnotic medication at 2200. The next morning
the client is drowsy and wants to sleep instead of eating breakfast. The
nurse is aware that this effect is most likely due to
A. reduced hepatic function.
B. reduced cardiac function.
C. delayed toxic effect.
D. first-pass effect.
Answer A. Reduces hepatic function
Drugs are metabolized in the liver. Elderly patients are more likely to
have reduced liver function that prolongs the half-live of the
medications. As a result, the drug effect will last longer. This elderly
patient took sleeping pill the night before, and the drug effect extended
to the next morning due to the reduced liver function as evidence by
drowsiness.
2.It is expected that the nurse will question the health care provider if a
drug with a t(1/2) of a >24 hour drug is ordered to be given more than how
1/
15
, often.
A. Once daily
B. Every other day
C. Twice weekly
D. Once weekly
Answer A. Once daily
t(1/2) is half live. If the half life of a drug is 24 hours it should be only
given once daily. If the half life is 6 hours, it should only be given every
6 hours and so on...
3.The nurse notices that one of the client's drugs has a low therapeutic
index. What is the most important nursing implication of this?
A. A wide margin of safety
B. A narrow margin of safety
C. Measured 1 hour after administration
D. Measured 10 minutes after administration
Answer B. A narrow margin of safety.
Therapeutic index refers to the level at which a drug is more helpful
than harmful. If there is a low therapeutic index, then there is a narrow
margin of safety.
4.Which of the following nurse actions should be most appropriate for
2/
15
