FULL TEST BANK
TEST BANK FOR ABRAMS’ CLINICAL DRUG
THERAPY RATIONALES FOR NURSING
PRACTICE 13TH EDITION BY GERALYN
FRANDSEN; SANDRA S. PENNINGTON
PRINTED PDF | ORIGINAL DIRECTLY FROM THE PUBLISHER | 100%
VERIFIED ANSWERS | DOWNLOAD IMMEDIATELY AFTER THE
,Chapter 1, The Foundation Of Pharmacology: Quality And Safety
1. A Woman Diagnosed With Obsessive–Compulsive Disorder Has Been Prescribed
Oral Paroxetine Hydrochloride. What Is The Expected Effect For This
Prescription?
A. Curative Effect On Symptoms
B. Systemic Effect On Symptoms
C. Local Effect On Symptoms
D. Parenteral Effect On Symptoms
Answer: B
Rationale: Drugs That Produce Systemic Effects Are Taken Into The Body, Circulated
Through The Bloodstream To Their Sites Of Action In Various Body Tissues, And
Eventually Eliminated From The Body. Curative Agents Are Given To Cure A Disease
Process. In This Case, Paroxetine Hydrochloride Will Control The Symptoms But Not Cure
The Disorder. Drugs With Local Effects, Such As Sunscreen And Local Anesthetics, Act
Mainly At The Site Of Application. Paroxetine Hydrochloride Is Not Administered
Parenterally. Parenteral Agents Are Administered Subcutaneously, Intramuscularly, Or
Intravenously.
Pts: 1 Ref: P. 3, Introduction Obj: 1
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Understand Not: Multiple Choice
2. A Client Has Been Prescribed An Antibiotic. This Medication Is A Naturally
Occurring Substance That Has Been Chemical Modified. What Is Another Name
For This Type Of Medication?
A. Synthetic Drug
B. Semisynthetic Drug
C. Biotechnology Drug
D. Prototype Drug
Answer: B
Rationale: Semisynthetic Drugs (E.G., Many Antibiotics) Are Naturally Occurring
Substances That Have Been Chemically Modified. Synthetic Drugs Are More Standardized
In Their Chemical Characteristics, More Consistent In Their Effects, And Less Likely To
Produce Allergic Reactions. Biotechnology Drugs Involve Manipulating Dna And Rna And
Recombining Genes Into Hybrid Molecules That Can Be Inserted Into Living Organisms.
Prototype Drugs Are The First Drug Of A Particular Group To Be Developed.
Pts: 1 Ref: P. 3, Drug Sources Obj: 1
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Understand Not: Multiple Choice
3. Which Classification Applies To Morphine?
A. Central Nervous System Depressant
B. Central Nervous System Stimulant
, C. Anti-Inflammatory
D. Antihypertensive
Answer: A
Rationale: Drugs Are Classified According To Their Effects On Particular Body Systems,
Their Therapeutic Uses, And Their Chemical Characteristics. Morphine Is Classified As A
Central Nervous System Depressant And Will Produce This Effect In The Client. A Central
Nervous System Stimulant Increases Attention And Raises Mood. An Anti-Inflammatory
Agent Decreases Inflammation At The Site Of Tissue Or Joint Inflammation. An
Antihypertensive Agent Reduces Blood Pressure.
Pts: 1 Ref: P. 3, Drug Classifications And
Prototypes Obj: 1
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Remember Not: Multiple Choice
4. A Client Is Administered Amoxicillin. The Generic Name Of This Medication Belongs To
Which Drug Group?
A. Selective Serotonin Reuptake Inhibitors
B. Diuretics
C. Penicillins
D. Ace Inhibitors
Answer: C
Rationale: The Generic Name Often Indicates The Drug Group (E.G., Drugs With Generic
GRADESBOOST.CO
Names Ending In ―Cillin‖ Are Penicillins). Selective Serotonin Reuptake Inhibitors Are
Medications That Have Antidepressant Effects; Ssri Is A Broad Classification, Not A
Generic Name. Diuretics Are Medications That Increase Urine Output; Diuretic Is A Broad
Classification, Not A Generic Name. Ace Inhibitor Is The Broad Classification For The
Angiotensin Receptor Blockers, Not The Generic Name.
Pts: 1 Ref: P. 3, Drug Names Obj: 2
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Understand Not: Multiple Choice
5. The Administration Of Diphenhydramine Is Regulated By Which U.S. Government Agency?
A. Public Health Service
B. Federal Trade Commission
C. Occupational Safety And Health Administration
D. Food And Drug Administration
, Rationale: The Food And Drug Administration Approves Drugs For Over-The-Counter
Availability, Including The Transfer Of Drugs From Prescription To Otc Status, And May
Require Clinical Trials To Determine The Safety And Effectiveness Of Otc Use. The
Public Health Service Is Regulated By The State To Maintain The Health Of Individual
Citizens Of The State. The Federal Trade Commission Regulates Imports And Exports
Throughout The Nation. The Occupational Safety And Health Administration Regulates
Safety Within The Workplace.
Pts: 1 Ref: P. 4, Prescription And Nonprescription
Drugs Obj: 4
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Understand Not: Multiple Choice
6. In The U.S., The Administration Of Anabolic Steroids Is Regulated By Which Law?
A. The Food, Drug, And Cosmetic Act Of 1938
B. The Comprehensive Drug Abuse Prevention And Control Act
C. The Harrison Narcotic Act
D. The Sherley Amendment
Answer: B
Rationale: The Comprehensive Drug Abuse Prevention And Control Act Regulates The
Manufacture And Distribution Of Narcotics, Stimulants, Depressants, Hallucinogens, And
Anabolic Steroids. The Food, Drug, And Cosmetic Act Of 1938 Revised And Broadened
Fda Powers And Responsibilities, Giving The Fda Control Over Drug Safety. The Harrison
Narcotic Act Restricted The Importation, Manufacture, Sale, And Use Of Opium, Cocaine,
Marijuana, And Other Drugs That The Act D e f i gn erd aads E
nasrcboo
tio
cssth.Ecsohm
.T erley Amendment
Of 1912 Prohibited Fraudulent Claims Of Drug Effectiveness.
Pts: 1 Ref: P. 4, Prescription And Nonprescription
Drugs Obj: 3
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Remember Not: Multiple Choice
7. A Nurse Is Responsible For Maintaining An Accurate Count And Record Of The
Controlled Substances On The Nursing Division. This Nursing Action Is Regulated By
Which
U.S. Law Oragency?
A. The Food, Drug, And Cosmetic Act Of 1938
B. The Public Health Service
C. The Drug Enforcement Administration
D. The Sherley Amendment
Answer: C
, Rationale: The Drug Enforcement Administration Enforces The Controlled Substances
Act. Under This Enforcement, Nurses Are Responsible For Storing Controlled Substances
In Locked Containers, Administering Them Only To The People For Whom They Are
Prescribed, Recording Each Dose Given, And Maintaining An Accurate Inventory. The
Food, Drug, And Cosmetic Actof 1938 Revised And Broadened Fda Powers And
Responsibilities, Giving The Fda Control Over Drug Safety. The Public Health Service Is
Regulated By The State To Maintain The Health Of Individual Citizens Of The State. The
Sherley Amendment Of 1912 Prohibited Fraudulent Claims Of Drug Effectiveness.
Pts: 1 Ref: P. 7, Testing Procedure Obj: 4
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Understand Not: Multiple Choice
8. In Phase 1 Clinical Trials, The Potential Uses And Effects Of A New Drug Are
Determined By Which Method?
A. Administering Doses To Healthy Volunteers
B. Administering Doses To People With The Disease
C. Administering In Placebo-Controlled Design
D. Calculating The Risk-To-Benefit Ratio
Answer: A
Rationale: Phase 1 Studies Allow For The Administration Of The Medication To Healthy
Volunteers To Determine Safe Dosages, Routes Of Administration, Absorption,
Metabolism, Excretion, And Toxicity. In Phase 2 Studies, A Few Doses Are Given To A
Certain Number Of Subjects With The Disease Orgsr apdtoemsb
ym foor O
wshit
ch.Tcho
eMd ru g Is Being
Studied And Responses Are Compared With Those Of Healthy Subjects. Placebo-Controlled
Designs Are Used In Phase 3 Studies, In Which Half Of The Subjects Receive The New
Drug And Half Receive The Placebo.
Calculating The Risk-To-Benefit Ratio Is Used In Phase 2 Studies To Determine Whether
The Potential Benefits Of The Drug Outweigh The Risks.
Pts: 1 Ref: P. 7, Testing Procedure Obj: 5
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Understand Not: Multiple Choice
9. A New Medication For The Treatment Of Alzheimer’s Disease Is Being Administered To A
Group Of Subjects With The Disease. The Subjects Receiving This Medication Are
Unaware Of Whether They Are Being Administered The Medication Or A Placebo. This
Testing Occurs In Which Phase?
A. Phase 1
B. Phase 2
C. Phase 3
D. Phase 4
Answer: C
, Rationale: In Phase 3, The Drug Is Given To A Larger And More Representative Group Of
Subjects. In Double-Blind, Placebo-Controlled Designs, Half Of The Subjects Receive The
New Drug And Half Receive A Placebo (An Inactive Substance Similar In Appearance To
The Actual Drug), With Neither Subjects Nor Researchers Knowing Which Subjects
Receive Which Formulation. In Phase 1, A Few Doses Are Given To A Certain Number Of
Healthy Volunteers To Determine Safe Dosages, Routes Of Administration, Absorption,
Metabolism, Excretion, And Toxicity. In Phase 2, A Few Doses Are Given To A Certain
Number Of Subjects With The Disease Or Symptom For Which The Drug Is Being Studied
And Responses Are Compared With Those Of Healthy Subjects. In Phase 4, The Fda
Evaluates The Data From The First Three Phases For Drug Safety And Effectiveness,
Allows The Drug To Be Marketed For General Use, And Requires Manufacturers To
Continue Monitoring The Drug’s Effects.
Pts: 1 Ref: P. 7, Testing Procedure Obj: 5
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Understand Not: Multiple Choice
10. Which Organization Is Responsible For Approving New Drugs In The United States?
A. The American Medical Association (Ama)
B. The American Pharmaceutical Association (Apa)
C. The Food And Drug Administration (Fda)
D. The U.S. Pharmacopeia
Answer: C
Rationale: The Food And Drug Administration Is Responsible For Approving New Drugs
In The United States. The Am eri cagn rmaeddiec s
a l baos o
s oscitat.Iocnorempres ents The Health Care
Providers Of The United States. The American Pharmaceutical Association Represents The
Pharmacists Of The United States. The U.S. Pharmacopeia Was Adopted In 1906 And Is
Issued Every 5 Years Under The Supervision Of A National Committee Of Pharmacists,
Scientists, And Health Care Providers To Provide Information Concerning Drug Purity And
Strength.
Pts: 1 Ref: P. 7, Testing Procedure Obj: 3 Nat:
Client Needs: Safe And Effective Care Environment: Management Of Care Top:
Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Remember Not: Multiple Choice
11. A Client With A Long-Standing Dermatologic Health Problem Has Been Advised To
Use A Drug With A Local Effect. The Nurse Should Recognize What Characteristic Of
This Drug?
A. It Affects Only The Organ System In Which It Is Metabolized.
B. The Drug Requires Application At Multiple Sites.
C. It Is Effective Only As Long As It Is In Contact With Skin.
D. The Drug Acts Primarily At The Site Where It Is
Applied. Answer: D
, Rationale: Drugs With Local Effects, Such As Sunscreen Lotions And Local Anesthetics,
Act Mainly At The Site Of Application. Those With Systemic Effects Are Taken Into The
Body, Circulated Through The Bloodstream To Their Sites Of Action In Various Body
Tissues, And Eventually Eliminated From The Body. A Drug With Local Effect Does Not
Necessarily Have To Be Applied At Multiple Sites, And Its Action May Affect Tissues
Long After Contact.
Pts: 1 Ref: P. 3, Introduction Obj: 1
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Analyze Not: Multiple Choice
12. What Is The Primary Importance Of A Black Box Warning?
A. It Will Result In The Medication Being Removed From The Market.
B. It Acknowledges That The Medication Has Been Tested On Only A Selected
Portion Of The Population.
C. It Suggests That The Prescription Of The Medication Be Avoided When Treating
Certain Populations.
D. It Alerts Health Care Professionals Of The Potential Of Serious Adverse
Effects Associated With The Medication.
Answer: D
Rationale: Black Box Warnings Identify The Fact That A Drug Can Cause Serious Adverse
Effects. Subsequent Withdrawal Of Approved And Marketed Drugs Has Occurred, Usually
Because Of Serious Adverse Effects That Become Evident Only When The Drugs Are
Used In A Large, Diverse Population. The Warning Does Not Address Testing Or Target
Populations.
Pts: 1 Ref: P. 7, Testing Procedure Obj: 4
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Analyze Not: Multiple Choice
13. A Health Care Facility Is Complying With The Mandates Of U.S. The Drug
Enforcement Administration (Dea) Concerning Schedule Ii Medications When
Implementing Which Nursing Intervention? Select All That Apply.
A. Access To Narcotics Is Controlled By Key Or Codes.
B. Narcotics Are Administered By Prescriptions Only.
C. Only Selected Narcotics May Be Automatically Renewed.
D. The Administration Of Individual Narcotic Doses Is Recorded In Specific
Unit Documentation.
E. Any Recognized Discrepancy Involving A Narcotic Must Be Reported
To The Appropriate Facility Authority.
Answer: A, B, D, E
Rationale: Nurses Are Responsible For Storing Controlled Substances In Locked
Containers, Administering Them Only To The People For Whom They Are Prescribed,
Recording Each Dosegiven On Agency Narcotic Sheets And On The Client’s
Medication Administration Record, Maintaining An Accurate Inventory, And Reporting
Discrepancies To The Proper Authorities. Prescriptions For Schedule Ii Drugs Cannot
Be Refilled; A New Prescription Is Required.
, Pts: 1 Ref: P. 7, Testing Procedure Obj: 5
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Analyze Not: Multiple Select
14. Which Medication Reference Is Considered To Be An Authoritative, Well-Respected
Source Of Information? Select All That Apply.
A. American Hospital Formulary Service
B. Drug Facts And Comparisons
C. Physicians’ Desk Reference
D. Lippincott’s Nursing Drug Guide
E. Package Inserts Provided With Each Medication
Answer: A, B
Rationale: An Authoritative Source Is A Work Known To Be Reliable Because Its
Authority Or Authenticity Is Widely Recognized By Experts In The Field. Both The
American Hospital Formulary Service And The Drug Facts And Comparisons Are
Authoritative Sources Of Drug Information That Have Been Recognized As Reliable
Sources Of Medication Information. The Physicians’ Desk Reference Is Published Yearly
And Contains Manufacturers’ Published Inserts For Selected Drugs. The Package Inserts
Are Produced By The Drug Manufacturers And Do Not Necessarily Contain The Details
Included In The Correct Options. Lippincott’s Nursing Drug Guide Is An Example Of A
Drug Handbook, Not A Compilation Of Manufacturers’ Insertsand Intended As A Student
Resource.
Pts: 1 Ref:Grpa. 1d1e, S
sobuo
rcoes
s Otf.Dcruogminformation Obj: 7
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Understand Not: Multiple Select
15. A Nursing Student In A Pharmacology Class Should Be Encouraged To Study
The Medicationsaccording To Which Categorization? Select All That Apply.
A. Prototype
B. Controlled Substance
C. Drug Use
D. Generic Names
E. Therapeutic Classification
Answer: A, E
Rationale: The Nursing Student Should Concentrate On Therapeutic Classifications And
Their Prototypes. Controlled Substances Limit The Medications Studied To One Broad
Classification.Drug Use Is Only One Part Of The Broad Classification. Generic Names
Are Only One Aspect Ofthe Medication.
Pts: 1 Ref: P. 12, Strategies For Studying
Pharmacology Obj: 6
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
, Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Understand Not: Multiple Select
16. A Client Diagnosed With An Autoimmune Disorder Has Just Been Prescribed A Synthetic
Drug. Which Characteristic Is A Noted Advantage Of Synthetic Drugs?
A. The Client Is At A Lesser Risk For An Allergic Reaction.
B. The Client Will Require Less Frequent Dosing.
C. The Medication Will Be Available On An Over-The-Counter Basis.
D. The Medication Is Available In A Wider Variety Of Administration Routes.
Answer: A
Rationale: Synthetic Drugs Are More Standardized In Their Chemical Characteristics,
More Consistent In Their Effects, And Less Likely To Produce Allergic Reactions. They
Do Not Necessarily Require Less Frequent Dosing And May Or May Not Be Available Otc.
They Are Not Noted To Be Available In A Wider Variety Of Administration Routes Than
Naturally Occurring Substances.
Pts: 1 Ref: P. 3, Drug Sources Obj: 1
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Understand Not: Multiple Choice
17. A Client Is Confused And Has Stated To The Nurse, ―I Wasn’t Sure Whether I’m
Supposed To Taketylenol Or Acetaminophen.‖ To Best Address The Client’s Concern,
The Nurse Should Base The Response On What Information Concerning Generic And
Trade Names?
A. Prescribers Should Refergsr
olaeldyetosgbeo
neors
ictn.
Amceosmin Their Recommendations
And Written Prescriptions.
B. A Generic Name Is Independent Of Any Particular Drug Manufacturer.
C. Generic Names Change Frequently, But Trade Names Are More Consistent.
D. Prescribers Should Refer Solely To Trade Names In Their
Recommendations And Written Prescriptions.
Answer: B
Rationale: A Generic Name Is Related To The Chemical Or Official Name And Is
Independent Of The Manufacturer. Drugs May Be Prescribed And Dispensed By Generic Or
Trade Name. Generic Names Do Not Change, While Trade Names Vary According To
Time And Place.
Pts: 1 Ref: P. 3, Drug Names Obj: 2
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Analyze Not: Multiple Choice
18. What Is The Primary Purpose Of American Drug Laws?
A. To Ensure Maximum Choice For Consumers
B. To Expedite The Workload Of Health Care Providers
C. To Protect The Safety Of The Public
D. To Enhance The Efficient Delivery Of Health Care
, Answer: C
Rationale: The Main Goal Of Drug Laws Is To Protect The Public By Ensuring That Drugs
Marketed For Therapeutic Purposes Are Safe And Effective. Efficiency And Choice Are
Valid Considerations, But Neither Is The Primary Goal Of American Drug Legislation.
Workload Is Expedited When Delivery Of Health Care Is Efficient.
Pts: 1 Ref: P. 4, Prescription And Nonprescription
Drugs Obj: 3
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Understand Not: Multiple Choice
19. A Nurse Who Provides Care On A Postsurgical Unit Frequently Administers Schedule
Ii Drugs Toclients. Which Aspect Of Administering These Drugs Falls Under The
Auspices Of The
U.S. Drug Enforcement Administration?
A. Performing A Thorough Client Assessment Prior To Administration
B. Recording Each Dose Administration On An Agency Narcotic Sheet
C. Informing Clients Of The Potential Risks And Benefits Of Such Drugs Prior To
The First Dose
D. Assessing The Client Shortly After Administration To Ensure Existence Of The
Expected Therapeutic Effect
Answer: B
Rationale: Nurses Are Responsible For Storing Controlled Substances In Locked
Containers, Administering Them Only To People For Whom They Are Prescribed,
Recording Each Dose Given On Agency Narcotic Sheets Ag ndroandte
hescblio
enot’ss tm.Ec
dio
camtion
Administration Record, Maintaining
An Accurate Inventory, And Reporting Discrepancies To The Proper Authorities. The Other
Given Actions Are Appropriate Nursing Activities, But They Are Not Within The Scope Of
The Dea Authority.
Pts: 1 Ref: P. 7, Testing Procedure Obj: 5
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Analyze Not: Multiple Choice
20. Trials Of A New Drug Are Scheduled To Begin Soon. The Testing Methodology Will
Integrate The Stipulations Of The National Institutes Of Health (Nih) Revitalization Act.
According To This Act, The Manufacturer Must Address Which Requirement?
A. Independently Fund The Entire Testing Process.
B. Make The Results Of The Testing Process Publicly Available.
C. Include Women And Minorities In The Testing Process.
D. Exclude Any Potential For Financial Gain During The Testing
Process. Answer: C
TEST BANK FOR ABRAMS’ CLINICAL DRUG
THERAPY RATIONALES FOR NURSING
PRACTICE 13TH EDITION BY GERALYN
FRANDSEN; SANDRA S. PENNINGTON
PRINTED PDF | ORIGINAL DIRECTLY FROM THE PUBLISHER | 100%
VERIFIED ANSWERS | DOWNLOAD IMMEDIATELY AFTER THE
,Chapter 1, The Foundation Of Pharmacology: Quality And Safety
1. A Woman Diagnosed With Obsessive–Compulsive Disorder Has Been Prescribed
Oral Paroxetine Hydrochloride. What Is The Expected Effect For This
Prescription?
A. Curative Effect On Symptoms
B. Systemic Effect On Symptoms
C. Local Effect On Symptoms
D. Parenteral Effect On Symptoms
Answer: B
Rationale: Drugs That Produce Systemic Effects Are Taken Into The Body, Circulated
Through The Bloodstream To Their Sites Of Action In Various Body Tissues, And
Eventually Eliminated From The Body. Curative Agents Are Given To Cure A Disease
Process. In This Case, Paroxetine Hydrochloride Will Control The Symptoms But Not Cure
The Disorder. Drugs With Local Effects, Such As Sunscreen And Local Anesthetics, Act
Mainly At The Site Of Application. Paroxetine Hydrochloride Is Not Administered
Parenterally. Parenteral Agents Are Administered Subcutaneously, Intramuscularly, Or
Intravenously.
Pts: 1 Ref: P. 3, Introduction Obj: 1
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Understand Not: Multiple Choice
2. A Client Has Been Prescribed An Antibiotic. This Medication Is A Naturally
Occurring Substance That Has Been Chemical Modified. What Is Another Name
For This Type Of Medication?
A. Synthetic Drug
B. Semisynthetic Drug
C. Biotechnology Drug
D. Prototype Drug
Answer: B
Rationale: Semisynthetic Drugs (E.G., Many Antibiotics) Are Naturally Occurring
Substances That Have Been Chemically Modified. Synthetic Drugs Are More Standardized
In Their Chemical Characteristics, More Consistent In Their Effects, And Less Likely To
Produce Allergic Reactions. Biotechnology Drugs Involve Manipulating Dna And Rna And
Recombining Genes Into Hybrid Molecules That Can Be Inserted Into Living Organisms.
Prototype Drugs Are The First Drug Of A Particular Group To Be Developed.
Pts: 1 Ref: P. 3, Drug Sources Obj: 1
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Understand Not: Multiple Choice
3. Which Classification Applies To Morphine?
A. Central Nervous System Depressant
B. Central Nervous System Stimulant
, C. Anti-Inflammatory
D. Antihypertensive
Answer: A
Rationale: Drugs Are Classified According To Their Effects On Particular Body Systems,
Their Therapeutic Uses, And Their Chemical Characteristics. Morphine Is Classified As A
Central Nervous System Depressant And Will Produce This Effect In The Client. A Central
Nervous System Stimulant Increases Attention And Raises Mood. An Anti-Inflammatory
Agent Decreases Inflammation At The Site Of Tissue Or Joint Inflammation. An
Antihypertensive Agent Reduces Blood Pressure.
Pts: 1 Ref: P. 3, Drug Classifications And
Prototypes Obj: 1
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Remember Not: Multiple Choice
4. A Client Is Administered Amoxicillin. The Generic Name Of This Medication Belongs To
Which Drug Group?
A. Selective Serotonin Reuptake Inhibitors
B. Diuretics
C. Penicillins
D. Ace Inhibitors
Answer: C
Rationale: The Generic Name Often Indicates The Drug Group (E.G., Drugs With Generic
GRADESBOOST.CO
Names Ending In ―Cillin‖ Are Penicillins). Selective Serotonin Reuptake Inhibitors Are
Medications That Have Antidepressant Effects; Ssri Is A Broad Classification, Not A
Generic Name. Diuretics Are Medications That Increase Urine Output; Diuretic Is A Broad
Classification, Not A Generic Name. Ace Inhibitor Is The Broad Classification For The
Angiotensin Receptor Blockers, Not The Generic Name.
Pts: 1 Ref: P. 3, Drug Names Obj: 2
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Understand Not: Multiple Choice
5. The Administration Of Diphenhydramine Is Regulated By Which U.S. Government Agency?
A. Public Health Service
B. Federal Trade Commission
C. Occupational Safety And Health Administration
D. Food And Drug Administration
, Rationale: The Food And Drug Administration Approves Drugs For Over-The-Counter
Availability, Including The Transfer Of Drugs From Prescription To Otc Status, And May
Require Clinical Trials To Determine The Safety And Effectiveness Of Otc Use. The
Public Health Service Is Regulated By The State To Maintain The Health Of Individual
Citizens Of The State. The Federal Trade Commission Regulates Imports And Exports
Throughout The Nation. The Occupational Safety And Health Administration Regulates
Safety Within The Workplace.
Pts: 1 Ref: P. 4, Prescription And Nonprescription
Drugs Obj: 4
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Understand Not: Multiple Choice
6. In The U.S., The Administration Of Anabolic Steroids Is Regulated By Which Law?
A. The Food, Drug, And Cosmetic Act Of 1938
B. The Comprehensive Drug Abuse Prevention And Control Act
C. The Harrison Narcotic Act
D. The Sherley Amendment
Answer: B
Rationale: The Comprehensive Drug Abuse Prevention And Control Act Regulates The
Manufacture And Distribution Of Narcotics, Stimulants, Depressants, Hallucinogens, And
Anabolic Steroids. The Food, Drug, And Cosmetic Act Of 1938 Revised And Broadened
Fda Powers And Responsibilities, Giving The Fda Control Over Drug Safety. The Harrison
Narcotic Act Restricted The Importation, Manufacture, Sale, And Use Of Opium, Cocaine,
Marijuana, And Other Drugs That The Act D e f i gn erd aads E
nasrcboo
tio
cssth.Ecsohm
.T erley Amendment
Of 1912 Prohibited Fraudulent Claims Of Drug Effectiveness.
Pts: 1 Ref: P. 4, Prescription And Nonprescription
Drugs Obj: 3
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Remember Not: Multiple Choice
7. A Nurse Is Responsible For Maintaining An Accurate Count And Record Of The
Controlled Substances On The Nursing Division. This Nursing Action Is Regulated By
Which
U.S. Law Oragency?
A. The Food, Drug, And Cosmetic Act Of 1938
B. The Public Health Service
C. The Drug Enforcement Administration
D. The Sherley Amendment
Answer: C
, Rationale: The Drug Enforcement Administration Enforces The Controlled Substances
Act. Under This Enforcement, Nurses Are Responsible For Storing Controlled Substances
In Locked Containers, Administering Them Only To The People For Whom They Are
Prescribed, Recording Each Dose Given, And Maintaining An Accurate Inventory. The
Food, Drug, And Cosmetic Actof 1938 Revised And Broadened Fda Powers And
Responsibilities, Giving The Fda Control Over Drug Safety. The Public Health Service Is
Regulated By The State To Maintain The Health Of Individual Citizens Of The State. The
Sherley Amendment Of 1912 Prohibited Fraudulent Claims Of Drug Effectiveness.
Pts: 1 Ref: P. 7, Testing Procedure Obj: 4
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Understand Not: Multiple Choice
8. In Phase 1 Clinical Trials, The Potential Uses And Effects Of A New Drug Are
Determined By Which Method?
A. Administering Doses To Healthy Volunteers
B. Administering Doses To People With The Disease
C. Administering In Placebo-Controlled Design
D. Calculating The Risk-To-Benefit Ratio
Answer: A
Rationale: Phase 1 Studies Allow For The Administration Of The Medication To Healthy
Volunteers To Determine Safe Dosages, Routes Of Administration, Absorption,
Metabolism, Excretion, And Toxicity. In Phase 2 Studies, A Few Doses Are Given To A
Certain Number Of Subjects With The Disease Orgsr apdtoemsb
ym foor O
wshit
ch.Tcho
eMd ru g Is Being
Studied And Responses Are Compared With Those Of Healthy Subjects. Placebo-Controlled
Designs Are Used In Phase 3 Studies, In Which Half Of The Subjects Receive The New
Drug And Half Receive The Placebo.
Calculating The Risk-To-Benefit Ratio Is Used In Phase 2 Studies To Determine Whether
The Potential Benefits Of The Drug Outweigh The Risks.
Pts: 1 Ref: P. 7, Testing Procedure Obj: 5
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Understand Not: Multiple Choice
9. A New Medication For The Treatment Of Alzheimer’s Disease Is Being Administered To A
Group Of Subjects With The Disease. The Subjects Receiving This Medication Are
Unaware Of Whether They Are Being Administered The Medication Or A Placebo. This
Testing Occurs In Which Phase?
A. Phase 1
B. Phase 2
C. Phase 3
D. Phase 4
Answer: C
, Rationale: In Phase 3, The Drug Is Given To A Larger And More Representative Group Of
Subjects. In Double-Blind, Placebo-Controlled Designs, Half Of The Subjects Receive The
New Drug And Half Receive A Placebo (An Inactive Substance Similar In Appearance To
The Actual Drug), With Neither Subjects Nor Researchers Knowing Which Subjects
Receive Which Formulation. In Phase 1, A Few Doses Are Given To A Certain Number Of
Healthy Volunteers To Determine Safe Dosages, Routes Of Administration, Absorption,
Metabolism, Excretion, And Toxicity. In Phase 2, A Few Doses Are Given To A Certain
Number Of Subjects With The Disease Or Symptom For Which The Drug Is Being Studied
And Responses Are Compared With Those Of Healthy Subjects. In Phase 4, The Fda
Evaluates The Data From The First Three Phases For Drug Safety And Effectiveness,
Allows The Drug To Be Marketed For General Use, And Requires Manufacturers To
Continue Monitoring The Drug’s Effects.
Pts: 1 Ref: P. 7, Testing Procedure Obj: 5
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Understand Not: Multiple Choice
10. Which Organization Is Responsible For Approving New Drugs In The United States?
A. The American Medical Association (Ama)
B. The American Pharmaceutical Association (Apa)
C. The Food And Drug Administration (Fda)
D. The U.S. Pharmacopeia
Answer: C
Rationale: The Food And Drug Administration Is Responsible For Approving New Drugs
In The United States. The Am eri cagn rmaeddiec s
a l baos o
s oscitat.Iocnorempres ents The Health Care
Providers Of The United States. The American Pharmaceutical Association Represents The
Pharmacists Of The United States. The U.S. Pharmacopeia Was Adopted In 1906 And Is
Issued Every 5 Years Under The Supervision Of A National Committee Of Pharmacists,
Scientists, And Health Care Providers To Provide Information Concerning Drug Purity And
Strength.
Pts: 1 Ref: P. 7, Testing Procedure Obj: 3 Nat:
Client Needs: Safe And Effective Care Environment: Management Of Care Top:
Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Remember Not: Multiple Choice
11. A Client With A Long-Standing Dermatologic Health Problem Has Been Advised To
Use A Drug With A Local Effect. The Nurse Should Recognize What Characteristic Of
This Drug?
A. It Affects Only The Organ System In Which It Is Metabolized.
B. The Drug Requires Application At Multiple Sites.
C. It Is Effective Only As Long As It Is In Contact With Skin.
D. The Drug Acts Primarily At The Site Where It Is
Applied. Answer: D
, Rationale: Drugs With Local Effects, Such As Sunscreen Lotions And Local Anesthetics,
Act Mainly At The Site Of Application. Those With Systemic Effects Are Taken Into The
Body, Circulated Through The Bloodstream To Their Sites Of Action In Various Body
Tissues, And Eventually Eliminated From The Body. A Drug With Local Effect Does Not
Necessarily Have To Be Applied At Multiple Sites, And Its Action May Affect Tissues
Long After Contact.
Pts: 1 Ref: P. 3, Introduction Obj: 1
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Analyze Not: Multiple Choice
12. What Is The Primary Importance Of A Black Box Warning?
A. It Will Result In The Medication Being Removed From The Market.
B. It Acknowledges That The Medication Has Been Tested On Only A Selected
Portion Of The Population.
C. It Suggests That The Prescription Of The Medication Be Avoided When Treating
Certain Populations.
D. It Alerts Health Care Professionals Of The Potential Of Serious Adverse
Effects Associated With The Medication.
Answer: D
Rationale: Black Box Warnings Identify The Fact That A Drug Can Cause Serious Adverse
Effects. Subsequent Withdrawal Of Approved And Marketed Drugs Has Occurred, Usually
Because Of Serious Adverse Effects That Become Evident Only When The Drugs Are
Used In A Large, Diverse Population. The Warning Does Not Address Testing Or Target
Populations.
Pts: 1 Ref: P. 7, Testing Procedure Obj: 4
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Analyze Not: Multiple Choice
13. A Health Care Facility Is Complying With The Mandates Of U.S. The Drug
Enforcement Administration (Dea) Concerning Schedule Ii Medications When
Implementing Which Nursing Intervention? Select All That Apply.
A. Access To Narcotics Is Controlled By Key Or Codes.
B. Narcotics Are Administered By Prescriptions Only.
C. Only Selected Narcotics May Be Automatically Renewed.
D. The Administration Of Individual Narcotic Doses Is Recorded In Specific
Unit Documentation.
E. Any Recognized Discrepancy Involving A Narcotic Must Be Reported
To The Appropriate Facility Authority.
Answer: A, B, D, E
Rationale: Nurses Are Responsible For Storing Controlled Substances In Locked
Containers, Administering Them Only To The People For Whom They Are Prescribed,
Recording Each Dosegiven On Agency Narcotic Sheets And On The Client’s
Medication Administration Record, Maintaining An Accurate Inventory, And Reporting
Discrepancies To The Proper Authorities. Prescriptions For Schedule Ii Drugs Cannot
Be Refilled; A New Prescription Is Required.
, Pts: 1 Ref: P. 7, Testing Procedure Obj: 5
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Analyze Not: Multiple Select
14. Which Medication Reference Is Considered To Be An Authoritative, Well-Respected
Source Of Information? Select All That Apply.
A. American Hospital Formulary Service
B. Drug Facts And Comparisons
C. Physicians’ Desk Reference
D. Lippincott’s Nursing Drug Guide
E. Package Inserts Provided With Each Medication
Answer: A, B
Rationale: An Authoritative Source Is A Work Known To Be Reliable Because Its
Authority Or Authenticity Is Widely Recognized By Experts In The Field. Both The
American Hospital Formulary Service And The Drug Facts And Comparisons Are
Authoritative Sources Of Drug Information That Have Been Recognized As Reliable
Sources Of Medication Information. The Physicians’ Desk Reference Is Published Yearly
And Contains Manufacturers’ Published Inserts For Selected Drugs. The Package Inserts
Are Produced By The Drug Manufacturers And Do Not Necessarily Contain The Details
Included In The Correct Options. Lippincott’s Nursing Drug Guide Is An Example Of A
Drug Handbook, Not A Compilation Of Manufacturers’ Insertsand Intended As A Student
Resource.
Pts: 1 Ref:Grpa. 1d1e, S
sobuo
rcoes
s Otf.Dcruogminformation Obj: 7
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Understand Not: Multiple Select
15. A Nursing Student In A Pharmacology Class Should Be Encouraged To Study
The Medicationsaccording To Which Categorization? Select All That Apply.
A. Prototype
B. Controlled Substance
C. Drug Use
D. Generic Names
E. Therapeutic Classification
Answer: A, E
Rationale: The Nursing Student Should Concentrate On Therapeutic Classifications And
Their Prototypes. Controlled Substances Limit The Medications Studied To One Broad
Classification.Drug Use Is Only One Part Of The Broad Classification. Generic Names
Are Only One Aspect Ofthe Medication.
Pts: 1 Ref: P. 12, Strategies For Studying
Pharmacology Obj: 6
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
, Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Understand Not: Multiple Select
16. A Client Diagnosed With An Autoimmune Disorder Has Just Been Prescribed A Synthetic
Drug. Which Characteristic Is A Noted Advantage Of Synthetic Drugs?
A. The Client Is At A Lesser Risk For An Allergic Reaction.
B. The Client Will Require Less Frequent Dosing.
C. The Medication Will Be Available On An Over-The-Counter Basis.
D. The Medication Is Available In A Wider Variety Of Administration Routes.
Answer: A
Rationale: Synthetic Drugs Are More Standardized In Their Chemical Characteristics,
More Consistent In Their Effects, And Less Likely To Produce Allergic Reactions. They
Do Not Necessarily Require Less Frequent Dosing And May Or May Not Be Available Otc.
They Are Not Noted To Be Available In A Wider Variety Of Administration Routes Than
Naturally Occurring Substances.
Pts: 1 Ref: P. 3, Drug Sources Obj: 1
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Understand Not: Multiple Choice
17. A Client Is Confused And Has Stated To The Nurse, ―I Wasn’t Sure Whether I’m
Supposed To Taketylenol Or Acetaminophen.‖ To Best Address The Client’s Concern,
The Nurse Should Base The Response On What Information Concerning Generic And
Trade Names?
A. Prescribers Should Refergsr
olaeldyetosgbeo
neors
ictn.
Amceosmin Their Recommendations
And Written Prescriptions.
B. A Generic Name Is Independent Of Any Particular Drug Manufacturer.
C. Generic Names Change Frequently, But Trade Names Are More Consistent.
D. Prescribers Should Refer Solely To Trade Names In Their
Recommendations And Written Prescriptions.
Answer: B
Rationale: A Generic Name Is Related To The Chemical Or Official Name And Is
Independent Of The Manufacturer. Drugs May Be Prescribed And Dispensed By Generic Or
Trade Name. Generic Names Do Not Change, While Trade Names Vary According To
Time And Place.
Pts: 1 Ref: P. 3, Drug Names Obj: 2
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Analyze Not: Multiple Choice
18. What Is The Primary Purpose Of American Drug Laws?
A. To Ensure Maximum Choice For Consumers
B. To Expedite The Workload Of Health Care Providers
C. To Protect The Safety Of The Public
D. To Enhance The Efficient Delivery Of Health Care
, Answer: C
Rationale: The Main Goal Of Drug Laws Is To Protect The Public By Ensuring That Drugs
Marketed For Therapeutic Purposes Are Safe And Effective. Efficiency And Choice Are
Valid Considerations, But Neither Is The Primary Goal Of American Drug Legislation.
Workload Is Expedited When Delivery Of Health Care Is Efficient.
Pts: 1 Ref: P. 4, Prescription And Nonprescription
Drugs Obj: 3
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Understand Not: Multiple Choice
19. A Nurse Who Provides Care On A Postsurgical Unit Frequently Administers Schedule
Ii Drugs Toclients. Which Aspect Of Administering These Drugs Falls Under The
Auspices Of The
U.S. Drug Enforcement Administration?
A. Performing A Thorough Client Assessment Prior To Administration
B. Recording Each Dose Administration On An Agency Narcotic Sheet
C. Informing Clients Of The Potential Risks And Benefits Of Such Drugs Prior To
The First Dose
D. Assessing The Client Shortly After Administration To Ensure Existence Of The
Expected Therapeutic Effect
Answer: B
Rationale: Nurses Are Responsible For Storing Controlled Substances In Locked
Containers, Administering Them Only To People For Whom They Are Prescribed,
Recording Each Dose Given On Agency Narcotic Sheets Ag ndroandte
hescblio
enot’ss tm.Ec
dio
camtion
Administration Record, Maintaining
An Accurate Inventory, And Reporting Discrepancies To The Proper Authorities. The Other
Given Actions Are Appropriate Nursing Activities, But They Are Not Within The Scope Of
The Dea Authority.
Pts: 1 Ref: P. 7, Testing Procedure Obj: 5
Nat: Client Needs: Physiological Integrity: Pharmacological And Parenteral Therapies
Top: Chapter: 1: The Foundation Of Pharmacology: Quality And Safety
Key: Integrated Process: Nursing Process
Blm: Cognitive Level: Analyze Not: Multiple Choice
20. Trials Of A New Drug Are Scheduled To Begin Soon. The Testing Methodology Will
Integrate The Stipulations Of The National Institutes Of Health (Nih) Revitalization Act.
According To This Act, The Manufacturer Must Address Which Requirement?
A. Independently Fund The Entire Testing Process.
B. Make The Results Of The Testing Process Publicly Available.
C. Include Women And Minorities In The Testing Process.
D. Exclude Any Potential For Financial Gain During The Testing
Process. Answer: C
