NR565/ NR 565 FINAL EXAM ADVANCED PHARMACOLOGY
2025 EXAM COMPLETE 220 QUESTIONS WITH DETAILED
VERIFIED ANSWERS (100% CORRECT) /ALREADY GRADED
A+ CHAMBERLAIN
1. In which patient population is Metformin contraindicated in?
yp yp yp yp yp yp yp
A. Diabetics with HA1c < 7.0% yp yp yp yp
B. Patients older than 50 yp yp yp
C. Alcoholics
D. Womensufferingfrominfertility ANS:C.Alcoholics
p
y yp yp yp yp yp p
y yp
2. What lab value suggests metformin might be contraindicated?
yp yp yp yp yp yp yp
A. eGFR <30 yp
B. Crea 0.8 yp
C. WBC 7.8 yp
D. Bun 17 ANS:A.eGFR <30
yp yp yp yp p
y yp yp
3. Whatmedicationiscontraindicatedtotreatdiabetesifapatientalreadyhas a
p
y p
y p
y p
y p
y p
y p
y p
y p
y p
y p
y yp
cardiac ejection fraction rate of 40%?
yp yp yp yp yp yp
A. Second Generation sulfonyureas yp yp
B. Thiazolidinediones
C. Dopamine Agonist yp
D. Glucosidase Inhibitor ANS:B.Thiazolidinediones yp yp yp yp p
y yp
4. Sabrina is a 35-year-old female who presents with complaints of fatigue,
yp yp yp yp yp yp yp yp yp yp
1/39
yp yp
,anxiety, and palpitations. She has a long history of obesity and reports that sheis
yp yp yp yp yp yp yp yp yp yp yp yp yp yp p
y
happythatshehaslost23poundsinthelast2months.Shealsoreports thatshehas
p
y p
y p
y p
y p
y p
y p
y p
y p
y p
y p
y p
y p
y p
y p
y yp p
y p
y
troublesleepingandherhusbandcomplainsthatsheiskeeping thehousetoo
p
y p
y p
y p
y yp p
y p
y p
y p
y p
y yp p
y p
y
cold.Physicalexamrevealsslighttachycardiaat104bpmanda slightly enlarged
p
y p
y p
y p
y p
y p
y p
y p
y p
y p
y p
y yp yp
thyroid.Thyroid testing reveals hyperthyroidism or Grave's disease.
yp p
y yp yp yp yp yp yp
Whichofthefollowingagentsisthefirst-linetreatmentforhyperthyroidismor
p
y p
y p
y p
y p
y p
y p
y p
y p
y p
y p
y
Grave's disease?
yp yp
A. Methimazole
B. Metoprolol
C. Allopurinol
D. Levothyroxine ANS:A.Methimazole yp yp yp p
y yp
5. Whichofthe following medicationswould be considered the first line of
yp yp yp yp yp yp yp yp yp yp yp
treatment for a newly diagnosed Diabetic patient with adequate renal and
yp yp yp yp yp yp yp yp yp yp yp
hepatic function?
yp yp
A:NovoLogSlidingScaleInsulin B:
p
y p
y p
y p
y yp
Liraglutide (Victoza)
yp yp
2/39
yp yp
,C:Oral Metformin
p
y yp
D:Glipizide ANS:C:Oral Metformin
p
y yp yp yp p
y yp yp
6. Of the following medications,which is most likely to cause hypoglycemia?
yp yp yp p
y yp yp yp yp yp yp
A. Metformin
B. Insulin
C. Incretin mimetics yp
D. Thiazolidinediones ANS:B.Insulin yp yp yp p
y yp
7. Whichsymptomsare most expectedof a patientdiagnosedwithhypothy-
yp yp yp yp yp yp yp yp yp yp
roidism?
yp
A. shortness of breath,wheezing,fatigue yp yp p
y p
y
B. tachycardia,insomnia,weight loss,goiter p
y p
y yp p
y
C. irritability,anxiety,dizziness,increased sweating yp yp yp y p
D. drypaleskin,brittlehair,fatigue,myxedema ANS:D.dryskin,brittlehair,fatigue,
p
y yp p
y yp p
y p
y yp yp yp p
y yp yp yp yp yp
myxedema
yp
8. Patients with an increased risk for UTIs and genital infections or an active
yp yp yp yp yp yp yp yp yp yp yp yp
diagnosis,shouldavoidwhatdrugclass/esfortreatmentofTypeIIDiabetes?
yp p
y p
y p
y p
y yp p
y p
y p
y p
y p
y yp
A. Thiazolidinediones (Glitazones) yp
B. Biguanide.
C. Sodium-GlucoseCotransporter2(SGLT-2)Inhibitors. p
y p
y p
y p
y
D. Alloftheabove. ANS:C.Sodium-GlucoseCotransporter2(SGLT-2)Inhibitors.
p
y yp p
y yp yp yp yp p
y yp yp yp yp yp
9. A 45-year-old patient with a history of type 2 diabetes presents to the clinic
yp yp yp yp yp yp yp yp yp yp yp yp yp
for a follow-up appointment.The healthcare provider has prescribed
yp yp yp yp p
y yp yp yp yp
metforminas part of the treatment plan.Which of the following statements
yp yp yp yp yp yp yp p
y yp yp yp yp
regarding metformin is correct?
yp yp yp yp
A. Metformin primarily stimulates insulin production from the pancreas. yp yp yp yp yp yp yp
3/39
yp yp
, B. Metforminreducesglucoselevelsprimarilybydecreasing insulinresis-
yp yp yp yp yp yp yp yp
tance.
yp
C. Metformin is associated with a risk of hypoglycemia.
yp yp yp yp yp yp yp
D. Metforminimprovesinsulinsensitivityandreduceshepaticglucosepro-
yp yp yp yp yp yp yp yp
duction. ANS: D.Metformin improves insulin sensitivity and reduces hepatic
yp yp yp yp yp yp yp yp yp yp yp yp
glucose production.
yp yp
10. InwhatpartofthebodyareSGLT-2(sodium-glucosecotransporter2)
p
y p
y p
y p
y p
y p
y p
y p
y p
y p
y
inhibitors active?
yp yp
A. Small intestine yp
4/39
yp yp
2025 EXAM COMPLETE 220 QUESTIONS WITH DETAILED
VERIFIED ANSWERS (100% CORRECT) /ALREADY GRADED
A+ CHAMBERLAIN
1. In which patient population is Metformin contraindicated in?
yp yp yp yp yp yp yp
A. Diabetics with HA1c < 7.0% yp yp yp yp
B. Patients older than 50 yp yp yp
C. Alcoholics
D. Womensufferingfrominfertility ANS:C.Alcoholics
p
y yp yp yp yp yp p
y yp
2. What lab value suggests metformin might be contraindicated?
yp yp yp yp yp yp yp
A. eGFR <30 yp
B. Crea 0.8 yp
C. WBC 7.8 yp
D. Bun 17 ANS:A.eGFR <30
yp yp yp yp p
y yp yp
3. Whatmedicationiscontraindicatedtotreatdiabetesifapatientalreadyhas a
p
y p
y p
y p
y p
y p
y p
y p
y p
y p
y p
y yp
cardiac ejection fraction rate of 40%?
yp yp yp yp yp yp
A. Second Generation sulfonyureas yp yp
B. Thiazolidinediones
C. Dopamine Agonist yp
D. Glucosidase Inhibitor ANS:B.Thiazolidinediones yp yp yp yp p
y yp
4. Sabrina is a 35-year-old female who presents with complaints of fatigue,
yp yp yp yp yp yp yp yp yp yp
1/39
yp yp
,anxiety, and palpitations. She has a long history of obesity and reports that sheis
yp yp yp yp yp yp yp yp yp yp yp yp yp yp p
y
happythatshehaslost23poundsinthelast2months.Shealsoreports thatshehas
p
y p
y p
y p
y p
y p
y p
y p
y p
y p
y p
y p
y p
y p
y p
y yp p
y p
y
troublesleepingandherhusbandcomplainsthatsheiskeeping thehousetoo
p
y p
y p
y p
y yp p
y p
y p
y p
y p
y yp p
y p
y
cold.Physicalexamrevealsslighttachycardiaat104bpmanda slightly enlarged
p
y p
y p
y p
y p
y p
y p
y p
y p
y p
y p
y yp yp
thyroid.Thyroid testing reveals hyperthyroidism or Grave's disease.
yp p
y yp yp yp yp yp yp
Whichofthefollowingagentsisthefirst-linetreatmentforhyperthyroidismor
p
y p
y p
y p
y p
y p
y p
y p
y p
y p
y p
y
Grave's disease?
yp yp
A. Methimazole
B. Metoprolol
C. Allopurinol
D. Levothyroxine ANS:A.Methimazole yp yp yp p
y yp
5. Whichofthe following medicationswould be considered the first line of
yp yp yp yp yp yp yp yp yp yp yp
treatment for a newly diagnosed Diabetic patient with adequate renal and
yp yp yp yp yp yp yp yp yp yp yp
hepatic function?
yp yp
A:NovoLogSlidingScaleInsulin B:
p
y p
y p
y p
y yp
Liraglutide (Victoza)
yp yp
2/39
yp yp
,C:Oral Metformin
p
y yp
D:Glipizide ANS:C:Oral Metformin
p
y yp yp yp p
y yp yp
6. Of the following medications,which is most likely to cause hypoglycemia?
yp yp yp p
y yp yp yp yp yp yp
A. Metformin
B. Insulin
C. Incretin mimetics yp
D. Thiazolidinediones ANS:B.Insulin yp yp yp p
y yp
7. Whichsymptomsare most expectedof a patientdiagnosedwithhypothy-
yp yp yp yp yp yp yp yp yp yp
roidism?
yp
A. shortness of breath,wheezing,fatigue yp yp p
y p
y
B. tachycardia,insomnia,weight loss,goiter p
y p
y yp p
y
C. irritability,anxiety,dizziness,increased sweating yp yp yp y p
D. drypaleskin,brittlehair,fatigue,myxedema ANS:D.dryskin,brittlehair,fatigue,
p
y yp p
y yp p
y p
y yp yp yp p
y yp yp yp yp yp
myxedema
yp
8. Patients with an increased risk for UTIs and genital infections or an active
yp yp yp yp yp yp yp yp yp yp yp yp
diagnosis,shouldavoidwhatdrugclass/esfortreatmentofTypeIIDiabetes?
yp p
y p
y p
y p
y yp p
y p
y p
y p
y p
y yp
A. Thiazolidinediones (Glitazones) yp
B. Biguanide.
C. Sodium-GlucoseCotransporter2(SGLT-2)Inhibitors. p
y p
y p
y p
y
D. Alloftheabove. ANS:C.Sodium-GlucoseCotransporter2(SGLT-2)Inhibitors.
p
y yp p
y yp yp yp yp p
y yp yp yp yp yp
9. A 45-year-old patient with a history of type 2 diabetes presents to the clinic
yp yp yp yp yp yp yp yp yp yp yp yp yp
for a follow-up appointment.The healthcare provider has prescribed
yp yp yp yp p
y yp yp yp yp
metforminas part of the treatment plan.Which of the following statements
yp yp yp yp yp yp yp p
y yp yp yp yp
regarding metformin is correct?
yp yp yp yp
A. Metformin primarily stimulates insulin production from the pancreas. yp yp yp yp yp yp yp
3/39
yp yp
, B. Metforminreducesglucoselevelsprimarilybydecreasing insulinresis-
yp yp yp yp yp yp yp yp
tance.
yp
C. Metformin is associated with a risk of hypoglycemia.
yp yp yp yp yp yp yp
D. Metforminimprovesinsulinsensitivityandreduceshepaticglucosepro-
yp yp yp yp yp yp yp yp
duction. ANS: D.Metformin improves insulin sensitivity and reduces hepatic
yp yp yp yp yp yp yp yp yp yp yp yp
glucose production.
yp yp
10. InwhatpartofthebodyareSGLT-2(sodium-glucosecotransporter2)
p
y p
y p
y p
y p
y p
y p
y p
y p
y p
y
inhibitors active?
yp yp
A. Small intestine yp
4/39
yp yp