Inhoud
Deel 1 Parasitologie .................................................................................................................................................................... 3
1. Inleiding .............................................................................................................................................................................. 3
2. Amoebe .............................................................................................................................................................................. 3
Entamoebe histolytica ........................................................................................................................................................ 4
Levenscyclus ................................................................................................................................................................... 4
Infecties .......................................................................................................................................................................... 4
Naegleria fowleri ................................................................................................................................................................ 5
Infecties .......................................................................................................................................................................... 5
3. Intestinale flagellaten: Gardia ............................................................................................................................................ 5
4. Hemoflagelaten .................................................................................................................................................................. 6
4.1 Leishmania .................................................................................................................................................................... 6
4.2 Afrikaanse trypanosoma............................................................................................................................................... 8
4.3 Amerikaanse trypanosoma ........................................................................................................................................... 9
Trypanosoma cruzi ......................................................................................................................................................... 9
5. Apicomplexa ..................................................................................................................................................................... 10
5.1 Plasmodium ................................................................................................................................................................ 10
Malaria ......................................................................................................................................................................... 10
5.2 Toxoplasma ................................................................................................................................................................ 13
Deel 2: Mycologie ..................................................................................................................................................................... 15
2.1 Gisten ............................................................................................................................................................................. 16
2.2 Filamenteuse fungi ......................................................................................................................................................... 16
2.3 Asexuele en sexuele reproductie ................................................................................................................................... 17
Asexueel ........................................................................................................................................................................... 17
Sexuele ............................................................................................................................................................................. 17
2.4 Mycosen ......................................................................................................................................................................... 19
2.4.1 Oppervlakkige mycosen........................................................................................................................................... 19
2.4.2 Cutane mycosen ...................................................................................................................................................... 19
3 dermatofyten............................................................................................................................................................. 19
Tinea/ ringworm ........................................................................................................................................................... 19
Onychomycose/ tinea unguium ................................................................................................................................... 19
2.4.3 Subcutane mycosen................................................................................................................................................. 19
2.4.4 Systemische mycosen .............................................................................................................................................. 20
Echte pathogenen ........................................................................................................................................................ 20
Opportunistische pathogenen ...................................................................................................................................... 20
1
,2
, Deel 1 Parasitologie
1. Inleiding
Parasitaire infecties
- Malaria > 200 milj/j
- Slaapziekte > 3000/ j
- Schistosoma > 250 milj
- Ascaris > 1miljard
Hygiëne belangrijk, sommige zijn opportunisten (mensen met zwakke immuniteit)
(vooral ontwikkelingslanden, ook westerse)
Parasitisme: Vorm van sybiose waarbij 1 partner afh van andere voor nutriënten/ protectie. Voordeel voor parasiet,
schadelijk voor gastheer.
- Ectoparasieten (teek op huid)
- Endoparasiet (in lichaam)
o Protozoa: eencellige EU zonder celwand (dus geen gist)
▪ Amoebidae
▪ Mastigophora = flagellaten
• Gardia
• Leishmania
• Trypanosoma
▪ Apicomplexa
• Plasmodium
• Toxoplasma
▪ (Ciliophora)
= Cilia zijn miniatuur flagellen/ trilharen.
Bv: Paramecium: pantoffeldiertje in water
. Balantidium coli: intestinale infectie, diarree, ernstig bij immunosuppressie
▪ (Microsporidia = fungi)
o Helminthes: wormen
2. Amoebe
2 zones in cytoplasma
- Buitenste laag: plasma gel
- Binneste laag: plasmasol
Pseudopodium
1. Voorkant: plasmagel laten groeien + polymerisatie
2. Achterkant: minder gel + depolarisatie
3
Deel 1 Parasitologie .................................................................................................................................................................... 3
1. Inleiding .............................................................................................................................................................................. 3
2. Amoebe .............................................................................................................................................................................. 3
Entamoebe histolytica ........................................................................................................................................................ 4
Levenscyclus ................................................................................................................................................................... 4
Infecties .......................................................................................................................................................................... 4
Naegleria fowleri ................................................................................................................................................................ 5
Infecties .......................................................................................................................................................................... 5
3. Intestinale flagellaten: Gardia ............................................................................................................................................ 5
4. Hemoflagelaten .................................................................................................................................................................. 6
4.1 Leishmania .................................................................................................................................................................... 6
4.2 Afrikaanse trypanosoma............................................................................................................................................... 8
4.3 Amerikaanse trypanosoma ........................................................................................................................................... 9
Trypanosoma cruzi ......................................................................................................................................................... 9
5. Apicomplexa ..................................................................................................................................................................... 10
5.1 Plasmodium ................................................................................................................................................................ 10
Malaria ......................................................................................................................................................................... 10
5.2 Toxoplasma ................................................................................................................................................................ 13
Deel 2: Mycologie ..................................................................................................................................................................... 15
2.1 Gisten ............................................................................................................................................................................. 16
2.2 Filamenteuse fungi ......................................................................................................................................................... 16
2.3 Asexuele en sexuele reproductie ................................................................................................................................... 17
Asexueel ........................................................................................................................................................................... 17
Sexuele ............................................................................................................................................................................. 17
2.4 Mycosen ......................................................................................................................................................................... 19
2.4.1 Oppervlakkige mycosen........................................................................................................................................... 19
2.4.2 Cutane mycosen ...................................................................................................................................................... 19
3 dermatofyten............................................................................................................................................................. 19
Tinea/ ringworm ........................................................................................................................................................... 19
Onychomycose/ tinea unguium ................................................................................................................................... 19
2.4.3 Subcutane mycosen................................................................................................................................................. 19
2.4.4 Systemische mycosen .............................................................................................................................................. 20
Echte pathogenen ........................................................................................................................................................ 20
Opportunistische pathogenen ...................................................................................................................................... 20
1
,2
, Deel 1 Parasitologie
1. Inleiding
Parasitaire infecties
- Malaria > 200 milj/j
- Slaapziekte > 3000/ j
- Schistosoma > 250 milj
- Ascaris > 1miljard
Hygiëne belangrijk, sommige zijn opportunisten (mensen met zwakke immuniteit)
(vooral ontwikkelingslanden, ook westerse)
Parasitisme: Vorm van sybiose waarbij 1 partner afh van andere voor nutriënten/ protectie. Voordeel voor parasiet,
schadelijk voor gastheer.
- Ectoparasieten (teek op huid)
- Endoparasiet (in lichaam)
o Protozoa: eencellige EU zonder celwand (dus geen gist)
▪ Amoebidae
▪ Mastigophora = flagellaten
• Gardia
• Leishmania
• Trypanosoma
▪ Apicomplexa
• Plasmodium
• Toxoplasma
▪ (Ciliophora)
= Cilia zijn miniatuur flagellen/ trilharen.
Bv: Paramecium: pantoffeldiertje in water
. Balantidium coli: intestinale infectie, diarree, ernstig bij immunosuppressie
▪ (Microsporidia = fungi)
o Helminthes: wormen
2. Amoebe
2 zones in cytoplasma
- Buitenste laag: plasma gel
- Binneste laag: plasmasol
Pseudopodium
1. Voorkant: plasmagel laten groeien + polymerisatie
2. Achterkant: minder gel + depolarisatie
3
