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Samenvatting van hoofdstuk 10 van het vak microbiologie in biomedische wetenschappen

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"Deze samenvatting geeft de inhoud weer van zowel de PowerPoint-presentaties als de lessen over hoofdstuk 10 'Bacteriën/ infecties gerelateerd met luchtwegen' binnen het vak Microbiologie van de opleiding Biomedische Wetenschappen.

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August 5, 2025
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Microbiologie: Medische Bacteriologie Hoofdstuk 10


Inhoud
10. Bacteriën/ infecties gerelateerd met luchtwegen ................................................................................................................ 3
10.1 Bovenste en onderste luchtwegen ................................................................................................................................. 3
Bovenste ............................................................................................................................................................................. 3
Onderste ............................................................................................................................................................................. 3
10.2 Microbiota luchtwegen .................................................................................................................................................. 3
10.3 Defensiemechanismen ................................................................................................................................................... 4
10.4 Infecties van/ via luchtwegen ......................................................................................................................................... 4
10.4.1 Infecties bovenste luchtwegen ................................................................................................................................ 4
Streptococcus pyogenes ................................................................................................................................................. 5
Corynebacterium diptheriae .......................................................................................................................................... 7
10.4.2 Infecties onderste luchtwegen ................................................................................................................................ 8
Bordetella pertussis ........................................................................................................................................................ 8
Streptococcus pneumoniae .......................................................................................................................................... 10
Mycoplasma pneumoniae ............................................................................................................................................ 12
Mycobacterium tuberculosis ........................................................................................................................................ 13
10.4.3 Invasieve infecties via luchtwegen ........................................................................................................................ 15
Heamophilus influenzae type b .................................................................................................................................... 15
Neisseria meningitidis .................................................................................................................................................. 15




1

,2

, 10. Bacteriën/ infecties gerelateerd met luchtwegen

10.1 Bovenste en onderste luchtwegen

Bovenste
= neus, sinussen, keel (tot strottenhoofd)

Via buis van Eustachius verbonden met middenoor

Omvangrijke microbiota



Onderste
= Trachea, bronchiën, bronchiolen, alveoli

Longmicrobioom




10.2 Microbiota luchtwegen

= Normale microbiota

- Neusgaten = als op huid
- Pharynx
o Straphylococcus spp.
o Streptococcus spp.
o Neisseria spp.
o Heamophilus spp.
o Corynebacterium spp.
• Bescherming tegen pathogenen, maar eventueel ook oorzaak infectie onderste luchtwegen of elders.
- Longen = pharynx
Evenwicht tussen immigratie en eliminatie
Relatieve groeisnelheid B




In bovenste longen zullen pathogenen
dankzij mucocellulair transport naar
mond getransporteerd worden
(vernietigd in maag).

In onderste longen geen mucus meer dus
enkel opruim door alveolaire macrofagen.




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