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Select the correct statement.
a) The hypothalamus itself produces the prostaglandins that reset its center for
temperature regulation.
b) Bacteria and viruses can provoke a fever in a human host, because they secret
the pyrogen interleukin 1.
c) Exogenous pyrogens stimulate phagocytic cells to produce prostaglandins, which
affect the hypothalamus. - ANSWER a
1. Which of the following substances is released from neurons in the GI tract and
produces smooth muscle relaxation?
(A) Secretin
(B) Gastrin
(C) Cholecystokinin (CCK)
(D) Vasoactive intestinal peptide (VIP)
(E) Gastric inhibitory peptide (GIP) - ANSWER d
2. Which of the following is the site of secretion of intrinsic factor?
(A) Gastric antrum
(B) Gastric fundus
(C) Duodenum
(D) Ileum
(E) Colon - ANSWER b
3. Vibrio cholerae causes diarrhea because it
(A) increases HCO3- secretory channels in intestinal epithelial cells
(B) increases Cl- secretory channels in crypt cells
(C) prevents the absorption of glucose and causes water to be retained in the intestinal
lumen isosmotically
(D) inhibits cyclic adenosine monophos- phate (cAMP) production in intestinal epithelial
cells
(E) inhibits inositol 1,4,5-triphosphate (IP3) production in intestinal epithelial cells -
ANSWER b
4. Cholecystokinin (CCK) has some gastrin-like properties because both CCK and
gastrin
(A) are released from G cells in the stomach
(B) are released from I cells in the duodenum
,(C) are members of the secretin-homologous family
(D) have five identical C-terminal amino acids
(E) have 90% homology of their amino acids - ANSWER d
5. Which of the following is transported in intestinal epithelial cells by a Na+-dependent
cotransport process?
(A) Fatty acids
(B) Triglycerides
(C) Fructose
(D) Alanine
(E) Oligopeptides - ANSWER d
6. A 49-year-old male patient with severe Crohn's disease has been unresponsive to
drug therapy and undergoes ileal resection. After the surgery, he will have steatorrhea
because
(A) the liver bile acid pool increases
(B) chylomicrons do not form in the intestinal lumen
(C) micelles do not form in the intestinal lumen
(D) dietary triglycerides cannot be digested
(E) the pancreas does not secrete lipase - ANSWER c
7. Cholecystokinin (CCK) inhibits
(A) gastric emptying
(B) pancreatic HCO3- secretion
(C) pancreatic enzyme secretion
(D) contraction of the gallbladder
(E) relaxation of the sphincter of Oddi - ANSWER a
8. Which of the following abolishes "receptive relaxation" of the stomach?
(A) Parasympathetic stimulation
(B) Sympathetic stimulation
(C) Vagotomy
(D) Administration of gastrin
(E) Administration of vasoactive intestinal peptide ( VIP)
(F) Administration of cholecystokinin (CCK) - ANSWER c
9. Secretion of which of the following substances is inhibited by low pH? (A)
Secretin
(B) Gastrin
(C) Cholecystokinin (CCK)
(D) Vasoactive intestinal peptide (VIP)
(E) Gastric inhibitory peptide (GIP) - ANSWER b
, 10. Which of the following is the site of secretion of gastrin?
(A) Gastric antrum
(B) Gastric fundus
(C) Duodenum
(D) Ileum
(E) Colon - ANSWER a
11. Micelle formation is necessary for the intestinal absorption of
(A) glycerol
(B) galactose
(C) leucine
(D) bile acids
(E) vitamin B12
(F) vitamin D - ANSWER f
12. Which of the following changes occurs during defecation?
(A) Internal anal sphincter is relaxed
(B) External anal sphincter is contracted
(C) Rectal smooth muscle is relaxed
(D) Intra-abdominal pressure is lower than
when at rest
(E) Segmentation contractions predominate - ANSWER a
Which of the following is characteristic of saliva?
(A) Hypotonicity relative to plasma
(B) A lower HCO3- concentration than plasma
(C) The presence of proteases
(D) Secretion rate that is increased by vagotomy
(E) Modification by the salivary ductal cells involves reabsorption of K+ and HCO3- -
ANSWER a
14. Which of the following substances is secreted in response to an oral glucose load?
(A) Secretin
(B) Gastrin
(C) Cholecystokinin (CCK)
(D) Vasoactive intestinal peptide (VIP)
(E) Glucose-dependent insulinotropic peptide (GIP) - ANSWER e
15. Which of the following is true about the secretion from the exocrine pancreas?
(A) It has a higher Cl- concentration than does plasma
(B) It is stimulated by the presence of HCO3- in the duodenum
(C) Pancreatic HCO3- secretion is increased by gastrin