NAPSR CNPR CHAPTER 12 BIOPHARMACEUTICAL DRUG
DEVELOPMENT ...VOCAB WORDS AND IMPORTANT
TERMS/ABBREVIATIONS QUESTIONS WITH 100%
ACCURATE SOLUTIONS
small molecule drugs - Accurate answers pharmaceuticals; new chemical entities (NCE's) that are
produced in manufacturing plants using techniques based on chemical reactions to reactants.
large molecule drugs - Accurate answers biopharmaceuticals; mainly protein based and resemble
natural biological compounds found in the human body. Manufactured in biological systems such as
living cells. these resemble the body's naturally occurring proteins, usually more potent than any other
disease treatments.
3 uses biopharmaceuticals are developed for - Accurate answers prophylactic (preventative)
therapeutic (antibodies) replacement therapy (hormones; growth factors)
biologics - Accurate answers a biological product subject to licensure under the Public Health
Service Act that is applicable to the prevention, treatment, or cure of disease or injuries to humans.
Vaccines, antibodies, cytokines, hormones, gene therapy, stem cells
vaccines - Accurate answers an antigen that has been treated to stimulate the immune system and
cause antibodies to be secreted to react against the foreign antigen.
pathogen - Accurate answers include mainly viruses, bacteria, parasites and fungi
virulent part - Accurate answers the part of a pathogen that causes disease
traditional vaccine preparation - Accurate answers 3 ways: attenuated vaccines, killed or
inactivated vaccines, toxoids
passaging - Accurate answers growing the pathogen in species other than the natural host
attenuated vaccine advantages - Accurate answers less expensive preparation, one dose sufficient,
attract the desired immunological response
attenuated vaccine disadvantages - Accurate answers potentially revert to virtulence, limited shelf
life
killed or inactivated vaccines - Accurate answers chemical or temperature treatments are normally
used to kill or inactivate a pathogen. formaldehyde, phenol, acetone or irradiation.
advantages of inactivated vaccines - Accurate answers non-reversal to virtulance, stable shelf life
DEVELOPMENT ...VOCAB WORDS AND IMPORTANT
TERMS/ABBREVIATIONS QUESTIONS WITH 100%
ACCURATE SOLUTIONS
small molecule drugs - Accurate answers pharmaceuticals; new chemical entities (NCE's) that are
produced in manufacturing plants using techniques based on chemical reactions to reactants.
large molecule drugs - Accurate answers biopharmaceuticals; mainly protein based and resemble
natural biological compounds found in the human body. Manufactured in biological systems such as
living cells. these resemble the body's naturally occurring proteins, usually more potent than any other
disease treatments.
3 uses biopharmaceuticals are developed for - Accurate answers prophylactic (preventative)
therapeutic (antibodies) replacement therapy (hormones; growth factors)
biologics - Accurate answers a biological product subject to licensure under the Public Health
Service Act that is applicable to the prevention, treatment, or cure of disease or injuries to humans.
Vaccines, antibodies, cytokines, hormones, gene therapy, stem cells
vaccines - Accurate answers an antigen that has been treated to stimulate the immune system and
cause antibodies to be secreted to react against the foreign antigen.
pathogen - Accurate answers include mainly viruses, bacteria, parasites and fungi
virulent part - Accurate answers the part of a pathogen that causes disease
traditional vaccine preparation - Accurate answers 3 ways: attenuated vaccines, killed or
inactivated vaccines, toxoids
passaging - Accurate answers growing the pathogen in species other than the natural host
attenuated vaccine advantages - Accurate answers less expensive preparation, one dose sufficient,
attract the desired immunological response
attenuated vaccine disadvantages - Accurate answers potentially revert to virtulence, limited shelf
life
killed or inactivated vaccines - Accurate answers chemical or temperature treatments are normally
used to kill or inactivate a pathogen. formaldehyde, phenol, acetone or irradiation.
advantages of inactivated vaccines - Accurate answers non-reversal to virtulance, stable shelf life
