NAPSRX CNPR EXAM (REVISED 18TH EDITION)
QUESTIONS WITH 100% ACCURATE ANSWERS
what does a STAT order mean? - Accurate answers a drug needed immediately and given only once
what information does the overdosage section of the labeling provide? - Accurate answers signs,
symptoms and treatment of acute overdoses
types of drug-drug interactions: - Accurate answers duplication, opposition (antagonism) and
alteration (p.51)
tolerance vs resistance - Accurate answers tolerance is the diminished response to a drug;
resistance is the cells ability to resist the effects of the drug on them.
abbreviated new drug application (ANDA) - Accurate answers the process by which applicants must
scientifically demonstrate to the FDA that their generic product is bioequivalent to or performs in the
same way as the innovator drug, no duplicate testing (p. 75)
the Hatch-Waxman Act of 1984 - Accurate answers -A.K.A. Drug Price Competition and Patent
Restoration Act
-made it easier to bring generic drugs to the market by requiring the FDA to only look at bioavailability
studies in order to approve an ANDA.
-gave protection to the research based manufacturers by providing a 30-month automatic cooling off
period once an ANDA is challenged for patent infringement (p. 75)
four basic transport mechanisms - Accurate answers passive diffusion, facilitated diffusion, active
transport, and pinocytosis (p. 95)
potency vs efficacy - Accurate answers potency: amount of drug necessary to produce desired
effect
efficacy: magnitude of maximal response that can be received from a drug
*efficacy is almost always more important that potency* (p. 106)
the four phases of clinical trials - Accurate answers phases I-IV (P. 124-126)
Key Parts Of A Clinical Paper (5) - Accurate answers Abstract, Introduction, methods, results,
discussion/conclusions (p. 128-129)
reliability vs validity - Accurate answers reliability = consistency and validity = accuracy
(p. 138; 143)
sampling error vs selection bias - Accurate answers sampling error is unbiased and is randomly
chosen from the population.
selection bias is when the sample was specifically chosen based on particular characteristics (p.142-143)
QUESTIONS WITH 100% ACCURATE ANSWERS
what does a STAT order mean? - Accurate answers a drug needed immediately and given only once
what information does the overdosage section of the labeling provide? - Accurate answers signs,
symptoms and treatment of acute overdoses
types of drug-drug interactions: - Accurate answers duplication, opposition (antagonism) and
alteration (p.51)
tolerance vs resistance - Accurate answers tolerance is the diminished response to a drug;
resistance is the cells ability to resist the effects of the drug on them.
abbreviated new drug application (ANDA) - Accurate answers the process by which applicants must
scientifically demonstrate to the FDA that their generic product is bioequivalent to or performs in the
same way as the innovator drug, no duplicate testing (p. 75)
the Hatch-Waxman Act of 1984 - Accurate answers -A.K.A. Drug Price Competition and Patent
Restoration Act
-made it easier to bring generic drugs to the market by requiring the FDA to only look at bioavailability
studies in order to approve an ANDA.
-gave protection to the research based manufacturers by providing a 30-month automatic cooling off
period once an ANDA is challenged for patent infringement (p. 75)
four basic transport mechanisms - Accurate answers passive diffusion, facilitated diffusion, active
transport, and pinocytosis (p. 95)
potency vs efficacy - Accurate answers potency: amount of drug necessary to produce desired
effect
efficacy: magnitude of maximal response that can be received from a drug
*efficacy is almost always more important that potency* (p. 106)
the four phases of clinical trials - Accurate answers phases I-IV (P. 124-126)
Key Parts Of A Clinical Paper (5) - Accurate answers Abstract, Introduction, methods, results,
discussion/conclusions (p. 128-129)
reliability vs validity - Accurate answers reliability = consistency and validity = accuracy
(p. 138; 143)
sampling error vs selection bias - Accurate answers sampling error is unbiased and is randomly
chosen from the population.
selection bias is when the sample was specifically chosen based on particular characteristics (p.142-143)
