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Biochem Rutgers Murphy Final EXAM WITH CORRECT ANSWERS

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Biochem Rutgers Murphy Final EXAM WITH CORRECT ANSWERS

Institution
Rutgers Murphy Biochem
Course
Rutgers Murphy Biochem

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Biochem Rutgers Murphy Final EXAM WITH CORRECT ANSWER
|\ |\ |\ |\ |\ |\ |\




1.conversion of acetyl-CoA to malonyl-CoA is inhibited by: Glucagon, |\ |\ |\ |\ |\ |\ |\ |\ |\




Epineph- rine, Palmitoyl-CoA |\ |\




2.The recycling rate of triacylglycerols to fatty acids is inhibited by: insulin
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\




3.Lipolysis is used to: degrade triacylglycerols |\ |\ |\ |\ |\




4.Glycerol from the hydrolysis of triacylglycerols is transported by the blood
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\




to the: liver
|\ |\




5.What is the major mechanistic difference in purine and pyrimidine biosyn-
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\




thesis: purines are synthesized on the ring of ribose
|\ |\ |\ |\ |\ |\ |\ |\




6.How many FADH2 molecules would be produced in the oxidation of palmitic
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\




acid (16:0 carbons): 7
|\ |\ |\




7.Myelin sheath: surrounds nerve cell axons and facilitates nerve
|\ |\ |\ |\ |\ |\ |\ |\ |\




impulse trans- mission |\ |\




8.patients with familial hypercholesterolmia: - have missing or defective
|\ |\ |\ |\ |\ |\ |\ |\ |\




LDL recpetors
|\




- are homozygous or heterozygous for a nonfunctional LDL receptor gene
|\ |\ |\ |\ |\ |\ |\ |\ |\




- Have very high levels of serum cholesterol
|\ |\ |\ |\ |\ |\




9. are the principal transporters of cholesteryl esters to tissues: low
|\ |\ |\ |\ |\ |\ |\ |\ |\




|\ density lipoprotein |\




10.the benzene ring of the aromatic amino acids is formed by:
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\




shikimate pathway |\




11.the pathway in which lipoproteins are transported from the liver to cells is
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\




referred to: endogenous pathway |\ |\ |\

1 |\/ |\36

,12.in simple diffusion a solute: is propelled by random molecular motion
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\




13.inorganic nitrogen is initially assimilated into which of the following amino
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\




acids: glutamine |\




14.which of the following is not one of the ketone bodies: b-Methylglutarate
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\




15.all of the following are purine bases except: thymine
|\ |\ |\ |\ |\ |\ |\ |\




16.prostaglandins are involved in: ovulation, inflammation, and digestion |\ |\ |\ |\ |\ |\ |\




17.the principal means of producing glycerol in the body: glyceroneogenesis
|\ |\ |\ |\ |\ |\ |\ |\ |\




18.depending on an animal's metabolic needs, fatty acids may be converted
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\




to triacylglycerols, energy or -------: used in membrane synthesis
|\ |\ |\ |\ |\ |\ |\ |\




19.Lipid molecules: fatty acids, steroids, isoprenoids, waxes
|\ |\ |\ |\ |\ |\




20.neutral fats belong to--------triacylglycerols
|\ |\ |\




21.------- is used to transport fatty acids into the mitochondria: carnitine
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\




22.SAM is a methyl donor in the synthesis of -----: methionine, creatine,
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\




phos- phatidylcholine
|\




23.fatty acid synthesis begins with the carboxylation of acetyl CoA to form
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\




-------Malonyl-CoA
24.Membrane remodeling: requires phospholipases and acyl transferases
|\ |\ |\ |\ |\ |\




2 |\/ |\36

,25.------, a product of the oxidation of odd-chain fatty acids, is converted to
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\




succinyl-CoA: propionyl-CoA |\




26.saturated fatty acids containing up to 16 carbon atoms are assembled |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\




in: cytoplasm
|\




27.which of the following is an alpha-keto acid/alpha-amino acid pair used in
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\




transamination: oxaloacetate/aspartate |\




28.Function of lipids: energy storage, components of biological |\ |\ |\ |\ |\ |\ |\ |\




membranes, in- sulation, source of acetyl-CoA |\ |\ |\ |\ |\




29.Why do most naturally occurring fatty acids have cis double bonds in
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\




them: the double bond results in a bend in the molecule lowering the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\




melting point of the molecule. |\ |\ |\ |\




30.The fixation of nitrogen requires: Fe-Mo protein, Fe protein, ferredoxin
|\ |\ |\ |\ |\ |\ |\ |\ |\




31.In plants fixed nitrogen is assimilated into: Glutamine
|\ |\ |\ |\ |\ |\ |\




32.The major route for protein degradation is: ubiquitin proteasomal system
|\ |\ |\ |\ |\ |\ |\ |\ |\




33.Fatty acid long carbon tails are referred to as: Acyl
|\ |\ |\ |\ |\ |\ |\ |\ |\




34.The double bonds in naturally occurring fatty acids are usually
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\




|\ isomers.: Cis |\




35.Protein channel requiring transport mechanisms include: Primary
|\ |\ |\ |\ |\ |\ |\




active transport and facilitated diffusion
|\ |\ |\ |\




36.All of the following statements concerning folic acid are true EXCEPT:: -
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\




Folic acid requires intrinsic factor for its absorption in the intestine
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\




37.the triacylglycerol cycle is: - a mechanism that regulates the level of fatty
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\




|\ acids that are available to the body for energy generation
|\ |\ |\ |\ |\ |\ |\ |\ |\




- a mechanism that hydrolyzes triacylglycerol
|\ |\ |\ |\



3 |\/ |\36

, - converts fatty acids to triacylglycerols |\ |\ |\ |\




38.waxes: are esters formed from long-chain fatty acids and long-chain
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\




alcohols
39.who makes who? estradiol vs. testosterone: the enzyme aromatase
|\ |\ |\ |\ |\ |\ |\ |\ |\




converts testosterone to estrogen |\ |\ |\




40.the function of dolichols is to: transport sugars in glycoprotein synthesi
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\




41.how many isoprene units does a diterpene contain: 4
|\ |\ |\ |\ |\ |\ |\ |\




42.glycolipids differ from sphingolipids in that they contain no: phosphate
|\ |\ |\ |\ |\ |\ |\ |\ |\




43.Intermediates in the nonoxidative phase of the pentose phosphate path- |\ |\ |\ |\ |\ |\ |\ |\ |\ |\




way include all of the following except?: dihydroxyacetone phosphate
|\ |\ |\ |\ |\ |\ |\ |\




44.which of the following is an oxidizing agent in fermentation: pyruvate
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\




45.gluconeogenesis occurs primarily in the: liver |\ |\ |\ |\ |\




46.in nucleosome structure, the histone ----- aids in stabilizing the wrapping
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\




of DNA around the protein octomer: H1
|\ |\ |\ |\ |\ |\




47.Which of the following does not contribute to the noncovalent interactions
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\




that stabilize the helical strands of DNA: phosphodiester bonds
|\ |\ |\ |\ |\ |\ |\ |\




4 |\/ |\36

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Institution
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Rutgers Murphy Biochem

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