Test Bank Complete_
Fundamentals Of Molecular Virology 2nd Edition,
By Nicholas H. Acheson
All Chapter 1-37| 10 Sections| Updated Edition With Verified Answers| Grade A+
From: [Bestmaxsolutions.Stuvia
,SECTION 1: INTRODUCTION TO VIROLOGY -------------------------------------------------------------------- 4
Chapter 1: Introduction To Virology -------------------------------------------------------------------------------------4
Chapter 2: Virus Structure And Assembly---------------------------------------------------------------------------- 18
Chapter 3: Virus Classification: The World Of Viruses ------------------------------------------------------------ 27
CHAPTER 4: Virus Entry --------------------------------------------------------------------------------------------------- 36
SECTION 2: VIRUSES OF BACTERIA AND ARCHAEA -------------------------------------------------------- 46
Chapter 5: Single-Stranded RNA Bacteriophages ------------------------------------------------------------------ 46
Chapter 6: Microviruses -------------------------------------------------------------------------------------------------- 56
Chapter 7: Bacteriophage T7 -------------------------------------------------------------------------------------------- 65
Chapter 8: Bacteriophage Lambda------------------------------------------------------------------------------------- 75
Chapter 9: Viruses Of Archaea ------------------------------------------------------------------------------------------ 84
SECTION 3: POSITIVE-STRAND RNA VIRUSES OF EUKARYOTES----------------------------------------- 93
Chapter 10: Cucumber Mosaic Virus ---------------------------------------------------------------------------------- 93
Chapter 11: Picornaviruses -------------------------------------------------------------------------------------------- 103
Chapter 12: Flaviviruses ------------------------------------------------------------------------------------------------ 113
Chapter 13: Togaviruses ------------------------------------------------------------------------------------------------ 122
Chapter 14: Coronaviruses --------------------------------------------------------------------------------------------- 132
SECTION 3: NEGATIVE-STRAND AND DOUBLE-STRANDED RNA VIRUSES OF EUKARYOTES --- 141
Chapter 15: Paramyxoviruses And Rhabdoviruses -------------------------------------------------------------- 141
Chapter 16: Filoviruses-------------------------------------------------------------------------------------------------- 151
Chapter 17: Bunyaviruses ---------------------------------------------------------------------------------------------- 160
Chapter 18: Influenza Viruses ----------------------------------------------------------------------------------------- 169
Chapter 19: Reoviruses ------------------------------------------------------------------------------------------------- 180
SECTION 5: SMALL DNA VIRUSES OF EUKARYOTES------------------------------------------------------ 190
Chapter 20: Parvoviruses ----------------------------------------------------------------------------------------------- 190
Chapter 21: Polyomaviruses ------------------------------------------------------------------------------------------- 200
Chapter 22: Papillomaviruses ----------------------------------------------------------------------------------------- 210
SECTION 6: LARGER DNA VIRUSES OF EUKARYOTES ---------------------------------------------------- 220
Chapter 23: Adenoviruses---------------------------------------------------------------------------------------------- 220
Chapter 24: Herpesviruses --------------------------------------------------------------------------------------------- 230
Chapter 25: Baculoviruses --------------------------------------------------------------------------------------------- 241
, Chapter 26: Poxviruses ------------------------------------------------------------------------------------------------- 251
Chapter 27: Viruses Of Algae And Mimivirus --------------------------------------------------------------------- 261
SECTION 7: VIRUSES THAT USE A REVERSE TRANSCRIPTASE------------------------------------------ 271
Chapter 28: Retroviruses ----------------------------------------------------------------------------------------------- 271
Chapter 29: Human Immunodeficiency Virus --------------------------------------------------------------------- 282
Chapter 30: Hepadnaviruses ------------------------------------------------------------------------------------------ 292
SECTION 8: VIROIDS AND PRIONS---------------------------------------------------------------------------- 303
Chapter 31: Viroids And Hepatitis Delta Virus -------------------------------------------------------------------- 303
Chapter 32: Prions ------------------------------------------------------------------------------------------------------- 312
SECTION 9: HOST DEFENSES AGAINST VIRUS INFECTION ---------------------------------------------- 322
Chapter 33: Intrinsic Cellular Defenses Against Virus Infection ---------------------------------------------- 322
Chapter 34: Innate And Adaptive Immune Responses To Virus Infection --------------------------------- 331
SECTION 10: ANTIVIRAL AGENTS AND VIRUS VECTORS ------------------------------------------------ 341
Chapter 35: Antiviral Vaccines ---------------------------------------------------------------------------------------- 341
Chapter 36: Antiviral Chemotherapy -------------------------------------------------------------------------------- 351
Chapter 37: Eukaryotic Virus Vectors ------------------------------------------------------------------------------- 361
,SECTION 1: INTRODUCTION TO VIROLOGY
Chapter 1: Introduction To Virology
Nicholas H. Acheson: Fundamentals of Molecular Virology 2nd Edition, Test Bank
QUESTION TYPE: MULTIPLE CHOICE
1) Which Of The Following Terms Describes The Protein Shell That Surrounds The
Viral Genome?
A) Capsid
B) Envelope
C) Matrix
D) Virion
E) Capsomere
ANSWER: A
The Capsid Is The Protein Shell That Encloses And Protects The Viral Genome. It Is
Composed Of Protein Subunits Called Capsomeres (Choice E), But The Shell As A
Whole Is Called The Capsid. The Envelope (Choice B) Is A Lipid Membrane That Some
Viruses Acquire From Host Cells. The Matrix (Choice C) Lies Between The Capsid And
Envelope In Some Viruses. The Virion (Choice D) Refers To The Complete, Infectious
Virus Particle.
2) Which Of The Following Would Not Be A Nucleic Acid Form Found In A Viral
Genome?
A) dsDNA
B) ssDNA
C) dsRNA
D) ssRNA
E) An RNA:DNA Hybrid
, ANSWER: E
Viruses Can Have Single- Or Double-Stranded DNA Or RNA As Their Genetic Material.
However, RNA:DNA Hybrids (E.G., Partial RNA And DNA Together) Are Not Found
As The Native Genome Of Viruses. Retroviruses, Like HIV, Form RNA:DNA
Intermediates During Replication, But Not As The Original Viral Genome.
3) Which Of The Following Is An Enzyme That Most RNA Viruses Encode In Their
Genome?
A) DNA-Dependent-RNA-Polymerase
B) RNA-Dependent-RNA-Polymerase
C) DNA-Dependent-DNA-Polymerase
D) DNA-Dependent-RNA-Polymerase
E) RNA-Dependent-Protein-Synthetase
ANSWER: B
RNA Viruses Need To Replicate Their RNA Genome, And To Do So, They Encode
RNA-Dependent RNA Polymerase (Rdrp). This Enzyme Can Synthesize RNA From An
RNA Template. Host Cells Do Not Have This Enzyme, So Viruses Must Bring Or
Encode It. The Other Options Describe Enzymes Found In Normal Host Cell Replication
Or Transcription, Not Typically Encoded By RNA Viruses.
4) Viruses Play A Major Role In The Ecology Of The Ocean By Doing Which Of The
Following?
A) By Infecting Photosynthetic Bacteria And Increasing Their Growth.
B) By Infecting Harmful Bacteria Found In The Ocean And Limiting Their Growth.
C) By Killing Off Fish And Preventing Them From Becoming Too Plentiful.
Fundamentals Of Molecular Virology 2nd Edition,
By Nicholas H. Acheson
All Chapter 1-37| 10 Sections| Updated Edition With Verified Answers| Grade A+
From: [Bestmaxsolutions.Stuvia
,SECTION 1: INTRODUCTION TO VIROLOGY -------------------------------------------------------------------- 4
Chapter 1: Introduction To Virology -------------------------------------------------------------------------------------4
Chapter 2: Virus Structure And Assembly---------------------------------------------------------------------------- 18
Chapter 3: Virus Classification: The World Of Viruses ------------------------------------------------------------ 27
CHAPTER 4: Virus Entry --------------------------------------------------------------------------------------------------- 36
SECTION 2: VIRUSES OF BACTERIA AND ARCHAEA -------------------------------------------------------- 46
Chapter 5: Single-Stranded RNA Bacteriophages ------------------------------------------------------------------ 46
Chapter 6: Microviruses -------------------------------------------------------------------------------------------------- 56
Chapter 7: Bacteriophage T7 -------------------------------------------------------------------------------------------- 65
Chapter 8: Bacteriophage Lambda------------------------------------------------------------------------------------- 75
Chapter 9: Viruses Of Archaea ------------------------------------------------------------------------------------------ 84
SECTION 3: POSITIVE-STRAND RNA VIRUSES OF EUKARYOTES----------------------------------------- 93
Chapter 10: Cucumber Mosaic Virus ---------------------------------------------------------------------------------- 93
Chapter 11: Picornaviruses -------------------------------------------------------------------------------------------- 103
Chapter 12: Flaviviruses ------------------------------------------------------------------------------------------------ 113
Chapter 13: Togaviruses ------------------------------------------------------------------------------------------------ 122
Chapter 14: Coronaviruses --------------------------------------------------------------------------------------------- 132
SECTION 3: NEGATIVE-STRAND AND DOUBLE-STRANDED RNA VIRUSES OF EUKARYOTES --- 141
Chapter 15: Paramyxoviruses And Rhabdoviruses -------------------------------------------------------------- 141
Chapter 16: Filoviruses-------------------------------------------------------------------------------------------------- 151
Chapter 17: Bunyaviruses ---------------------------------------------------------------------------------------------- 160
Chapter 18: Influenza Viruses ----------------------------------------------------------------------------------------- 169
Chapter 19: Reoviruses ------------------------------------------------------------------------------------------------- 180
SECTION 5: SMALL DNA VIRUSES OF EUKARYOTES------------------------------------------------------ 190
Chapter 20: Parvoviruses ----------------------------------------------------------------------------------------------- 190
Chapter 21: Polyomaviruses ------------------------------------------------------------------------------------------- 200
Chapter 22: Papillomaviruses ----------------------------------------------------------------------------------------- 210
SECTION 6: LARGER DNA VIRUSES OF EUKARYOTES ---------------------------------------------------- 220
Chapter 23: Adenoviruses---------------------------------------------------------------------------------------------- 220
Chapter 24: Herpesviruses --------------------------------------------------------------------------------------------- 230
Chapter 25: Baculoviruses --------------------------------------------------------------------------------------------- 241
, Chapter 26: Poxviruses ------------------------------------------------------------------------------------------------- 251
Chapter 27: Viruses Of Algae And Mimivirus --------------------------------------------------------------------- 261
SECTION 7: VIRUSES THAT USE A REVERSE TRANSCRIPTASE------------------------------------------ 271
Chapter 28: Retroviruses ----------------------------------------------------------------------------------------------- 271
Chapter 29: Human Immunodeficiency Virus --------------------------------------------------------------------- 282
Chapter 30: Hepadnaviruses ------------------------------------------------------------------------------------------ 292
SECTION 8: VIROIDS AND PRIONS---------------------------------------------------------------------------- 303
Chapter 31: Viroids And Hepatitis Delta Virus -------------------------------------------------------------------- 303
Chapter 32: Prions ------------------------------------------------------------------------------------------------------- 312
SECTION 9: HOST DEFENSES AGAINST VIRUS INFECTION ---------------------------------------------- 322
Chapter 33: Intrinsic Cellular Defenses Against Virus Infection ---------------------------------------------- 322
Chapter 34: Innate And Adaptive Immune Responses To Virus Infection --------------------------------- 331
SECTION 10: ANTIVIRAL AGENTS AND VIRUS VECTORS ------------------------------------------------ 341
Chapter 35: Antiviral Vaccines ---------------------------------------------------------------------------------------- 341
Chapter 36: Antiviral Chemotherapy -------------------------------------------------------------------------------- 351
Chapter 37: Eukaryotic Virus Vectors ------------------------------------------------------------------------------- 361
,SECTION 1: INTRODUCTION TO VIROLOGY
Chapter 1: Introduction To Virology
Nicholas H. Acheson: Fundamentals of Molecular Virology 2nd Edition, Test Bank
QUESTION TYPE: MULTIPLE CHOICE
1) Which Of The Following Terms Describes The Protein Shell That Surrounds The
Viral Genome?
A) Capsid
B) Envelope
C) Matrix
D) Virion
E) Capsomere
ANSWER: A
The Capsid Is The Protein Shell That Encloses And Protects The Viral Genome. It Is
Composed Of Protein Subunits Called Capsomeres (Choice E), But The Shell As A
Whole Is Called The Capsid. The Envelope (Choice B) Is A Lipid Membrane That Some
Viruses Acquire From Host Cells. The Matrix (Choice C) Lies Between The Capsid And
Envelope In Some Viruses. The Virion (Choice D) Refers To The Complete, Infectious
Virus Particle.
2) Which Of The Following Would Not Be A Nucleic Acid Form Found In A Viral
Genome?
A) dsDNA
B) ssDNA
C) dsRNA
D) ssRNA
E) An RNA:DNA Hybrid
, ANSWER: E
Viruses Can Have Single- Or Double-Stranded DNA Or RNA As Their Genetic Material.
However, RNA:DNA Hybrids (E.G., Partial RNA And DNA Together) Are Not Found
As The Native Genome Of Viruses. Retroviruses, Like HIV, Form RNA:DNA
Intermediates During Replication, But Not As The Original Viral Genome.
3) Which Of The Following Is An Enzyme That Most RNA Viruses Encode In Their
Genome?
A) DNA-Dependent-RNA-Polymerase
B) RNA-Dependent-RNA-Polymerase
C) DNA-Dependent-DNA-Polymerase
D) DNA-Dependent-RNA-Polymerase
E) RNA-Dependent-Protein-Synthetase
ANSWER: B
RNA Viruses Need To Replicate Their RNA Genome, And To Do So, They Encode
RNA-Dependent RNA Polymerase (Rdrp). This Enzyme Can Synthesize RNA From An
RNA Template. Host Cells Do Not Have This Enzyme, So Viruses Must Bring Or
Encode It. The Other Options Describe Enzymes Found In Normal Host Cell Replication
Or Transcription, Not Typically Encoded By RNA Viruses.
4) Viruses Play A Major Role In The Ecology Of The Ocean By Doing Which Of The
Following?
A) By Infecting Photosynthetic Bacteria And Increasing Their Growth.
B) By Infecting Harmful Bacteria Found In The Ocean And Limiting Their Growth.
C) By Killing Off Fish And Preventing Them From Becoming Too Plentiful.
