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ATI TEAS 7 Biology Review.
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Macromolecules:
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Carbohydrate, Lipid, Nucleic Acid, Protein, Enzyme
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Carbohydrate: Sugars and starches which body breaks down to glucose
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● Structural function: cellulose and chitin
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● Energy storage: amylose, amylopectin, glycogen
● Recognition molecules: glycoproteins and glycolipids
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Lipids: Fatty acids and their derivatives that are soluble in water
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● H and C and main components
● Fats
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● Hydrophobic- thus help separate aqueous compartments
● Store energy (fats, oils, adipose)
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Protein: Molecules composed of amino acids joined by peptide bonds
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● Monomer: amino acids (amino group + carboxylic acid)(20 types)
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● Keratin and Collagen (hydrophobic)- not soluble in water, found in structural protein
● Globular proteins are hydrophilic (hemoglobin, antibodies, enzymes)
● Function as transport carries or signal transfer la
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Nucleic Acids: Long molecules made of nucleotides; DNA and RNA
● DNA stores genetic material
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● Chromosomes
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● RNA is a messenger (mRNA) also rRNA and tRNA
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Enzymes: Class of protein that catalyze biochemical reactions
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● Not consumed in reaction
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● Speed up reaction by lowering activation energy
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● Exergonic: release energy
● Endergonic: require energy
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Energy is supplied and released as ATP
● Lock and Key (substrate must fit into enzymes active site)
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DNA and RNA
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DNA: macromolecule that contains coded instructions for the body to
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produce proteins
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● Nucleotide: the building block of DNA and RNA
● Nitrogenous Base: Adenine, Thymine, Guanine, and Cytosine
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● Purines: Adenine and Guanine
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● Pyrimidines: Thymine and Cytosine
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● Codon: Agroup of 3 nitrogenous bases used to synthesize amino
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acids (Synthesized from RNA during TRANSLATION)
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● Hydrogen Bonds: Connect a Purine to a Pyrimidine (A-T) and (C-G). Non-covalent, weak.
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o RNA: Uracil replaces Thymine
● Double Helix structure
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● Coded or read 5'→3'
● Sugar(pentose)-Phosphate backbone (deoxyribose and phosphate group- bound to 4 oxygen
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atoms)
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DNA Replication
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DNA Helicase: Unzips and Unwinds DNA strand
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DNA Primase: Generates RNA Primer. Act as a template for starting point of DNA Replication
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DNA Polymerase: Synthesize new DNA molecules by adding nucleotides to leading and lagging DNA
strands in 5'→3' direction
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Topoisomerase: Prevents supercoiling
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DNA Ligase: Joins DNA fragments together by forming phosphodiester bonds between nucleotides
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Okazaki Fragment: Short, newly synthesized DNA fragments that are formed on the lagging strand
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Single Strand Binding Protein: Stabilize structure during replication
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Leading Strand: Replicated continuously in the 3' to 5' direction
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Lagging Strand: Replicated discontinuously in short sections
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replica
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G2)
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Prophase
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Metaphase
Mitosis = “daughter cell” exact
Interphase (G1, S,
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Anaphase
Telophase
Cytokinesis
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Cell Cycle
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● Meiosis = “daughter cells” different genetic coding
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o Only happens in gametes*
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o 1st phase
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● chromosomes cross over
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● genetic material exchanged
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● tetrads of 4 chromatids formed
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□ Homologous pairs of chromatids are separated and go to different poles
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□2 cells go through 2nd cell division
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□ 4 daughter cells with different sets of chromosomes
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● Haploid : contains half genetic material of parent cell
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● Zygote- controls cell differentiation
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Tissues
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¾ groups of cells
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¾ Muscle, nerve, epithelial, connective
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1. Epithelial: (joined together tightly) ex. Skin
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2. Connective: (dense, loose, or fatty) ex. Bone tissue, cartilage, tendons, ligaments, fat,
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blood, lymph
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□Protects & binds body parts
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a. Cartilage: cushions & provides structural support
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i. Fibrous
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b. Blood: transports oxygen to cells & removes waste / ALSO carries hormones &
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