,
,Chapter 1: Orientation to Pharmacology
z z z z
Burchum: Lehne’s Pharmacology for Nursing Care, 11th Edition
z z z z z z z
MULTIPLEzCHOICE
1. Theznurseziszteachingzazpatientzhowzazmedicationzworksztoztreatzanzillness.zTozdozthis,ztheznu
rsezwillzrelyzonzknowledgezof:
a. clinicalzpharmacology.
b. drugzefficacy.
c. pharmacokinetics.
d. pharmacotherapeutics.
ANS:z D
Pharmacotherapeuticsziszthezstudyzofzthezusezofzdrugsztozdiagnose,ztreat,zandzpreventzconditions
.zClinicalzpharmacologyziszconcernedzwithzallzaspectszofzdrug–
humanzinteractions.zDrugzefficacyzmeasureszthezextentztozwhichzazgivenzdrugzcauseszanzintende
dzeffect.
Pharmacokineticsziszthezstudyzofzthezimpactzofzthezbodyzonzazdrug.
DIF: CognitivezLevel:zComprehension
REF:zFourzBasiczTermszTOP:z NursingzProcess:zImplementati
on
MSC:z NCLEXzClientzNeedszCategory:zPhysiologiczIntegrity:zPharmacologiczandzParenteralzTherapies
2. Whatzdoeszitzmeanzwhenzazdrugziszdescribedzaszeasyztozadminister?
a. Itzcanzbezstoredzindefinitelyzwithoutzneedzforzrefrigeration.
b. Itzdoesznotzinteractzsignificantlyzwithzotherzmedications.
c. Itzenhanceszpatientzadherenceztozthezdrugzregimen.
d. Itziszusuallyzrelativelyzinexpensiveztozproduce.
ANS:z C
Azmajorzbenefitzofzdrugszthatzarezeasyztozadministerziszthatzpatientsztakingzthemzarezmorezlikelyzt
ozcomplyzwithzthezdrugzregimen.zDrugszthatzarezeasyztozgivezmayzhavezthezotherzattributeszlisted
,zbutzthosezpropertieszarezindependentzofzeasezofzadministration.
DIF: CognitivezLevel:zComprehension
REF:zAdditionalzPropertieszofzanzIdealzDrug:zEasezofzAdministrationzTOP:
z NursingzProcess:zAssessment
MSC:z NCLEXzClientzNeedszCategory:zPhysiologiczIntegrity:zPharmacologiczandzParenteralzTherapies
3. Azpatientztellsztheznursezthatzhezwasztoldzbyzthezprescriberzthatzthezanalgesiczhezisztakingziszver
yzeffective.zWhichzstatementzbyzthezpatientzdemonstrateszanzunderstandingzofzthezdrug’szeffec
tiveness?
a. “Izdon’tzhaveztozworryzaboutztoxicity,zsincezitztakeszazlargezamountzofzthiszdrugztozca
usezanzoverdose.”
b. “Itzhasznozsidezeffectszandzdoesn’tzinteractzwithzotherzdrugs.”
c. “Izonlyzhaveztoztakezitzeveryz12zhours.”
d. “Itzmightzmakezmezsleepy,zandzitzlessenszpainzforzseveralzhourszatzaztime.”
ANS:z D
, Azdrugziszeffectivezifzitzproduceszthezintendedzeffects,zevenzifzitzalsozproduceszsidezeffects.zBecau
seznozdrugziszcompletelyzsafe,zthezlevelzofztoxicityzdoesznotzdeterminezeffectiveness.zAllzdrugszha
vezsidezeffectszandzmanyzreactzwithzotherzsubstances;zthesezdoznotzaffectzthezdrug’szeffectiveness
.zEasezofzadministrationziszindependentzofzazdrug’szeffectiveness.
DIF: CognitivezLevel:zComprehension
REF:zPropertieszofzanzIdealzDrugzTOP:z NursingzProcess:zEvaluation
MSC:z NCLEXzClientzNeedszCategory:zPhysiologiczIntegrity:zPharmacologiczandzParenteralzTherapies
MULTIPLEzRESPONSE
1. Whatzarezthezpropertieszofzanzidealzdrug?z(Selectzallzthatzapply.)
a. Irreversiblezaction
b. Predictability
c. Easezofzadministration
d. Chemicalzstability
e. Azsimpleztradezname
ANS:z B,zC,zD
Inzadditionztozpredictability,zeasezofzadministration,zandzchemicalzstability,zotherzpropertieszinc
ludezazreversiblezactionzsozthatzanyzharmzthezdrugzmayzcausezcanzbezundonezandzazsimplezgeneric
zname,zbecausez genericznameszarezusuallyzcomplex zandzdifficultztozrememberzandzpronounce.
DIF: CognitivezLevel:zComprehension
REF:zPropertieszofzanzIdealzDrugz|zAdditionalzPropertieszofzanzIdealzDrugzT
OP:z NursingzProcess:zAssessment
MSC:z NCLEXzClientzNeedszCategory:zPhysiologiczIntegrity:zPharmacologiczandzParenteralzTherapies
2. Beforezadministeringzazmedication,zwhatzdoesztheznursezneedztozknowztozevaluatezhow
individualzpatientzvariabilityzmightzaffectzthezpatient’szresponseztozthezmedication?z(Selectzallzth
atzapply.)
a. Chemicalzstabilityzofzthezmedication
b. Easezofzadministration
c. Familyzmedicalzhistory
d. Patient’szage
e. Patient’szdiagnosis
ANS:z C,zD,zE
Thezfamilyzmedicalzhistoryzcanzindicatezgeneticzfactorszthatzmayzaffectzazpatient’szresponseztozaz
medication.zPatientszofzdifferentzageszcanzrespondzdifferentlyztozmedications.zThezpatient’szillne
sszcanzaffectzhowzdrugszarezmetabolized.zThezchemicalzstabilityzofzthezmedicationzandzthezeasezof
zadministrationzarezpropertieszofzdrugs.
DIF: CognitivezLevel:zAnalysis
REF:zSourceszofzIndividualzVariationzTOP:z NursingzProcess:zImplementati
on
MSC:z NCLEXzClientzNeedszCategory:zPhysiologiczIntegrity:zReductionzofzRiskzPotential
,Chapter 1: Orientation to Pharmacology
z z z z
Burchum: Lehne’s Pharmacology for Nursing Care, 11th Edition
z z z z z z z
MULTIPLEzCHOICE
1. Theznurseziszteachingzazpatientzhowzazmedicationzworksztoztreatzanzillness.zTozdozthis,ztheznu
rsezwillzrelyzonzknowledgezof:
a. clinicalzpharmacology.
b. drugzefficacy.
c. pharmacokinetics.
d. pharmacotherapeutics.
ANS:z D
Pharmacotherapeuticsziszthezstudyzofzthezusezofzdrugsztozdiagnose,ztreat,zandzpreventzconditions
.zClinicalzpharmacologyziszconcernedzwithzallzaspectszofzdrug–
humanzinteractions.zDrugzefficacyzmeasureszthezextentztozwhichzazgivenzdrugzcauseszanzintende
dzeffect.
Pharmacokineticsziszthezstudyzofzthezimpactzofzthezbodyzonzazdrug.
DIF: CognitivezLevel:zComprehension
REF:zFourzBasiczTermszTOP:z NursingzProcess:zImplementati
on
MSC:z NCLEXzClientzNeedszCategory:zPhysiologiczIntegrity:zPharmacologiczandzParenteralzTherapies
2. Whatzdoeszitzmeanzwhenzazdrugziszdescribedzaszeasyztozadminister?
a. Itzcanzbezstoredzindefinitelyzwithoutzneedzforzrefrigeration.
b. Itzdoesznotzinteractzsignificantlyzwithzotherzmedications.
c. Itzenhanceszpatientzadherenceztozthezdrugzregimen.
d. Itziszusuallyzrelativelyzinexpensiveztozproduce.
ANS:z C
Azmajorzbenefitzofzdrugszthatzarezeasyztozadministerziszthatzpatientsztakingzthemzarezmorezlikelyzt
ozcomplyzwithzthezdrugzregimen.zDrugszthatzarezeasyztozgivezmayzhavezthezotherzattributeszlisted
,zbutzthosezpropertieszarezindependentzofzeasezofzadministration.
DIF: CognitivezLevel:zComprehension
REF:zAdditionalzPropertieszofzanzIdealzDrug:zEasezofzAdministrationzTOP:
z NursingzProcess:zAssessment
MSC:z NCLEXzClientzNeedszCategory:zPhysiologiczIntegrity:zPharmacologiczandzParenteralzTherapies
3. Azpatientztellsztheznursezthatzhezwasztoldzbyzthezprescriberzthatzthezanalgesiczhezisztakingziszver
yzeffective.zWhichzstatementzbyzthezpatientzdemonstrateszanzunderstandingzofzthezdrug’szeffec
tiveness?
a. “Izdon’tzhaveztozworryzaboutztoxicity,zsincezitztakeszazlargezamountzofzthiszdrugztozca
usezanzoverdose.”
b. “Itzhasznozsidezeffectszandzdoesn’tzinteractzwithzotherzdrugs.”
c. “Izonlyzhaveztoztakezitzeveryz12zhours.”
d. “Itzmightzmakezmezsleepy,zandzitzlessenszpainzforzseveralzhourszatzaztime.”
ANS:z D
, Azdrugziszeffectivezifzitzproduceszthezintendedzeffects,zevenzifzitzalsozproduceszsidezeffects.zBecau
seznozdrugziszcompletelyzsafe,zthezlevelzofztoxicityzdoesznotzdeterminezeffectiveness.zAllzdrugszha
vezsidezeffectszandzmanyzreactzwithzotherzsubstances;zthesezdoznotzaffectzthezdrug’szeffectiveness
.zEasezofzadministrationziszindependentzofzazdrug’szeffectiveness.
DIF: CognitivezLevel:zComprehension
REF:zPropertieszofzanzIdealzDrugzTOP:z NursingzProcess:zEvaluation
MSC:z NCLEXzClientzNeedszCategory:zPhysiologiczIntegrity:zPharmacologiczandzParenteralzTherapies
MULTIPLEzRESPONSE
1. Whatzarezthezpropertieszofzanzidealzdrug?z(Selectzallzthatzapply.)
a. Irreversiblezaction
b. Predictability
c. Easezofzadministration
d. Chemicalzstability
e. Azsimpleztradezname
ANS:z B,zC,zD
Inzadditionztozpredictability,zeasezofzadministration,zandzchemicalzstability,zotherzpropertieszinc
ludezazreversiblezactionzsozthatzanyzharmzthezdrugzmayzcausezcanzbezundonezandzazsimplezgeneric
zname,zbecausez genericznameszarezusuallyzcomplex zandzdifficultztozrememberzandzpronounce.
DIF: CognitivezLevel:zComprehension
REF:zPropertieszofzanzIdealzDrugz|zAdditionalzPropertieszofzanzIdealzDrugzT
OP:z NursingzProcess:zAssessment
MSC:z NCLEXzClientzNeedszCategory:zPhysiologiczIntegrity:zPharmacologiczandzParenteralzTherapies
2. Beforezadministeringzazmedication,zwhatzdoesztheznursezneedztozknowztozevaluatezhow
individualzpatientzvariabilityzmightzaffectzthezpatient’szresponseztozthezmedication?z(Selectzallzth
atzapply.)
a. Chemicalzstabilityzofzthezmedication
b. Easezofzadministration
c. Familyzmedicalzhistory
d. Patient’szage
e. Patient’szdiagnosis
ANS:z C,zD,zE
Thezfamilyzmedicalzhistoryzcanzindicatezgeneticzfactorszthatzmayzaffectzazpatient’szresponseztozaz
medication.zPatientszofzdifferentzageszcanzrespondzdifferentlyztozmedications.zThezpatient’szillne
sszcanzaffectzhowzdrugszarezmetabolized.zThezchemicalzstabilityzofzthezmedicationzandzthezeasezof
zadministrationzarezpropertieszofzdrugs.
DIF: CognitivezLevel:zAnalysis
REF:zSourceszofzIndividualzVariationzTOP:z NursingzProcess:zImplementati
on
MSC:z NCLEXzClientzNeedszCategory:zPhysiologiczIntegrity:zReductionzofzRiskzPotential
