ONS Chemotherapy Biotherapy
Certification Questions with verified
correct detailed Answers latest update
2025
What is unique about nitrosoureas agents? --- correct answer ---Able
to cross the blood-brain barrier; can be effective in treating some
brain tumors
Common nitrosoureas agents: --- correct answer ---Carmustine
(BiCNU)
Lomustine (CeeNu)
Streptozocin (Zanosar)
Hypersensitivity can occur with late doses of: --- correct answer ---
Carboplatin
These agents are typically categorized as highly emetogenic: ---
correct answer ---1. Alkylating agents
2. Nitrosoureas
,Pre-administration labs for alkylating agents and nitrosoureas: ---
correct answer ---BUN
Creatinine
CBC w/ diff
What is the medication Mesna used for? --- correct answer ---Bladder
protectant with administration of cyclophosphamide or ifosfamide
Instruct pts receiving ________ to avoid exposure to cold air and
consuming cold fluids for 3-4 days following treatment --- correct
answer ---Oxaliplatin
How do antimetabolites function? --- correct answer ---By blocking
DNA and RNA growth by interfering with enzymes needed for normal
cell metabolism
Antimetabolites work in the ___ phase. --- correct answer ---S
What types of cells are best affected by antimetabolites? --- correct
answer ---Cells with high division rates
,Common side effects of antimetabolites: --- correct answer ---
Myelosuppression
GI toxicities
Photosensitivity
Hand-foot syndrome
Common antimetabolite drugs: --- correct answer ---Azacitidine
Capecitabine
5-FU
Cytarabine
Decitabine
Methotrexate
The institute for Safe Medication Practices recommends what route of
administration for vincristine? --- correct answer ---IV piggyback via
gravity
Anthracycline antitumor abx work by: --- correct answer ---
Interfering with enzymes necessary for DNA to replicate in ALL
phases of the cell cycle
, The two major classifications of antitumor antibiotics are: --- correct
answer ---Anthracyclines
Non-anthracyclines
Common anthracycline antitumor abx: --- correct answer ---
Daunorubicin
Doxorubicin
Epirubicin
Idarubicin
The antitumor abx ___________ is not an anthracycline, but has
anthracycline-type properties. --- correct answer ---Mitoxantrone
Common non-anthracycline antitumor abx: --- correct answer ---
Actinomycin D
Mitomycin C
Bleomycin
Monitoring necessary with doxorubicin: --- correct answer ---Vesicant
--> extravasation
Cardiac function
Certification Questions with verified
correct detailed Answers latest update
2025
What is unique about nitrosoureas agents? --- correct answer ---Able
to cross the blood-brain barrier; can be effective in treating some
brain tumors
Common nitrosoureas agents: --- correct answer ---Carmustine
(BiCNU)
Lomustine (CeeNu)
Streptozocin (Zanosar)
Hypersensitivity can occur with late doses of: --- correct answer ---
Carboplatin
These agents are typically categorized as highly emetogenic: ---
correct answer ---1. Alkylating agents
2. Nitrosoureas
,Pre-administration labs for alkylating agents and nitrosoureas: ---
correct answer ---BUN
Creatinine
CBC w/ diff
What is the medication Mesna used for? --- correct answer ---Bladder
protectant with administration of cyclophosphamide or ifosfamide
Instruct pts receiving ________ to avoid exposure to cold air and
consuming cold fluids for 3-4 days following treatment --- correct
answer ---Oxaliplatin
How do antimetabolites function? --- correct answer ---By blocking
DNA and RNA growth by interfering with enzymes needed for normal
cell metabolism
Antimetabolites work in the ___ phase. --- correct answer ---S
What types of cells are best affected by antimetabolites? --- correct
answer ---Cells with high division rates
,Common side effects of antimetabolites: --- correct answer ---
Myelosuppression
GI toxicities
Photosensitivity
Hand-foot syndrome
Common antimetabolite drugs: --- correct answer ---Azacitidine
Capecitabine
5-FU
Cytarabine
Decitabine
Methotrexate
The institute for Safe Medication Practices recommends what route of
administration for vincristine? --- correct answer ---IV piggyback via
gravity
Anthracycline antitumor abx work by: --- correct answer ---
Interfering with enzymes necessary for DNA to replicate in ALL
phases of the cell cycle
, The two major classifications of antitumor antibiotics are: --- correct
answer ---Anthracyclines
Non-anthracyclines
Common anthracycline antitumor abx: --- correct answer ---
Daunorubicin
Doxorubicin
Epirubicin
Idarubicin
The antitumor abx ___________ is not an anthracycline, but has
anthracycline-type properties. --- correct answer ---Mitoxantrone
Common non-anthracycline antitumor abx: --- correct answer ---
Actinomycin D
Mitomycin C
Bleomycin
Monitoring necessary with doxorubicin: --- correct answer ---Vesicant
--> extravasation
Cardiac function
