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ATI: Pain & Inflammation, Infection, Immune System – Nursing Pharmacology Review – ATI Study Guide Summary

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This document summarizes key pharmacological concepts from the ATI Nursing curriculum related to pain and inflammation, infection control, and the immune system. It includes drug classifications, mechanisms of action, common side effects, contraindications, and nursing considerations. Ideal for exam preparation or quick reference during clinical rotations, this guide is structured and comprehensive.

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ATI: Pain & Inflammation, Infection, Immune System
– Nursing Pharmacology Review – ATI Study Guide
Summary


A nurse is caring for a client who is taking acetaminophen at regular intervals for mild
discomfort. The nurse should tell the client to report which of the following early indications
of acetaminophen toxicity? SATA

Diaphoresis

Palpitations

Shortness of Breath

Nausea

Diarrhea - CORRECT -🅰️🅰️☑️☑️Diaphoresis (sweating)

Nausea

Diarrhea



A nurse is caring for a client who currently takes furosemide and has a new prescription for
prednisone. The nurse should monitor the client for which of the following manifestations
during concurrent use of the two drugs?Hypercalcemia

Hypoglycemia

Hypothermia

Hypokalemia - CORRECT -🅰️🅰️☑️☑️Hypokalemia




Prednisone, a glucocorticoid, can cause hypokalemia. The risk for this electrolyte imbalance
increases when the client is taking potassium-depleting diuretics, such as furosemide. The
nurse should clarify the prescription with the provider and monitor the client's potassium
levels.




A nurse is caring for a client who is about to begin taking aspirin. The nurse should instruct
the client to report which of the following manifestations of salicylism?SATA

,Fever

Tinnitus

Diaphoresis

Thrombophlebitis

Dizziness - CORRECT -🅰️🅰️☑️☑️Fever

Tinnitus

Diaphoresis

Dizziness




A nurse is caring for a client who has a prescription for aspirin to treat an ankle sprain. The
nurse should instruct the client to report which of the following adverse drug reactions?

Polyuria

Bone Pain

Weight Gain

Infection - CORRECT -🅰️🅰️☑️☑️Weight Gain




Aspirin use can cause renal impairment, which can result in the retention of salt and water.
Clients should report reduced urine output, weight gain, edema, or bloating. The nurse
should monitor BUN and creatinine levels and stop aspirin therapy for clients who develop
signs of renal dysfunction




A nurse is reviewing the medical record of a client who has a new prescription for celecoxib.
The nurse should identify that which of the following conditions is a contraindication to
celecoxib?Rheumatoid arthritis

Ankylosing spondylitis

Sulfonamide allergy

Adrenocortical insufficiency - CORRECT -🅰️🅰️☑️☑️Sulfonamide Allergy

,Clients who are allergic to sulfonamides can have severe allergic reactions to celecoxib, a
COX-2 inhibitor. Clients who are allergic to salicylates can also react adversely to celecoxib




A nurse is planning care for a client who has stared taking prednisone. Which of the following
interventions should the nurse include?

Monitor the clients blood glucose

Administer an antacid 30 min prior to prednisone

Administer aspirin rather than NSAIDs if the client has pain

Monitor the client for hyperkalemia - CORRECT -🅰️🅰️☑️☑️Monitor the clients blood glucose

Prednisone can cause hyperglycemia the nurse should monitor the clients blood glucose
regularly




A nurse is reviewing the medical record of a client who reports taking acetaminophen at
home. The nurse should identify that which of the following client conditions is a
contraindication for acetaminophen?

Asthma

Diabetes mellitus

Heart Failure

Alcohol use disorder - CORRECT -🅰️🅰️☑️☑️Alcohol Use Disorder




Acetaminophen can cause liver toxicity. Clients who have a history of alcohol use disorder
should not take acetaminophen




A nurse is teaching a client who has a new prescription for prednisone. Which of the following
instructions should the nurse include?SATA

Reduce the dose during periods of stress

Discontinue the drug gradually

Report illness or infection

Increase intake of calcium and vitamin D

, Monitors for sings of gastric bleeding - CORRECT -🅰️🅰️☑️☑️Discontinue the drug gradually

Report illness or infection

Increase intake of calcium and vitamin D

Monitor for signs of gastric bleeding




A nurse is caring for a child who has a viral infection. The nurse should identify that which of
the following drugs can increase the risk of Reye syndrome in children who have viral
infections?Butorphanol

Acetaminophen

Tramadol

Aspirin - CORRECT -🅰️🅰️☑️☑️Aspirin




A nurse is caring for a client who has a new prescription for prednisone for long-term
treatment of rheumatoid arthritis. The nurse should monitor the client for which of the
following adverse drug reactions?Pulmonary embolism

Hepatitis

Bone loss

Breast cancer - CORRECT -🅰️🅰️☑️☑️Bone loss




Prednisone, a glucocorticoid, can cause osteoporosis, especially with long term use. Clients
who are taking the drug should increase weight-bearing activity and report back pain. The
nurse should monitor the client's bone density




A nurse is caring for a client who takes low-dose aspirin to prevent cardiovascular events. The
client asks the nurse about taking ibuprofen to treat rheumatoid arthritis. Which of the
following responses should the nurse make?"Ibuprofen will increase your risk for developing
salicylism."

"Ibuprofen will reduce the cardioprotective effects of low-dose aspirin."

"Low-dose aspirin will reduce the anti-inflammatory effects of ibuprofen."

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