SCNM Biochem Q2 Exam 2 questions with
correct answers
Purines |are |made |up |of |the |following |- |VERIFIED |ANSWER✔✔-Aspartic |Acid |(N1), |N10 |Formyl |THF |
(C2,8),glutamine |(N3,9), |glycine |(n7), |Co2 |(c6)
ADP |and |GDP |slow |down |the |rate |of |making |- |VERIFIED |ANSWER✔✔-PRPP
Rate |limiting |substance |in |purine |synthesis |- |VERIFIED |ANSWER✔✔-PRPP
Rate |limiting |enzyme |- |VERIFIED |ANSWER✔✔-Glutamine |phosphoribosyle |pyrophosphate |amido |
transferase
Glutamine |Phosphoribosyle |pyrophosphate |amido |transferase |is |inhibited |by |- |VERIFIED |ANSWER✔✔-
AMP,ADP,ATP |( |at |A |site) |GMP, |GDP, |GTP |( |at |g |site) |and |Azaserine
Nucleotide |- |VERIFIED |ANSWER✔✔-Phosphorylated |
Pentose
Nitrogenous |base
Nucleoside |- |VERIFIED |ANSWER✔✔-Pentose |
Nitrogenous |base
IMP |is |located |- |VERIFIED |ANSWER✔✔-Brain |and |liver
The |base |in |IMP |is |- |VERIFIED |ANSWER✔✔-Hypoxanthine
IMP |dehydrogenase |is |inhibited |by |- |VERIFIED |ANSWER✔✔-GMP
, Adenylosuccinate |synthetase |is |inhibited |by |- |VERIFIED |ANSWER✔✔-AMP
Adenylate |kinase |- |VERIFIED |ANSWER✔✔-AMP |+ |ATP |---> |GDP+ADP
Guanylate |Kinase |- |VERIFIED |ANSWER✔✔-GMP+ATP--> |GDP |+ |ADP
Nucleoside |diphosphate |kinase |- |VERIFIED |ANSWER✔✔-NDP+ATP--> |ADP |+ |NTP
ATP |and |GTP |are |used |for |- |VERIFIED |ANSWER✔✔-RNA |synthesis |( |transcription) |and |energy |transfers
|reactions
Nucleotides |break |- |VERIFIED |ANSWER✔✔-Phosphates
PNP |breaks |off |- |VERIFIED |ANSWER✔✔-Sugars
DATP |inhibits |- |VERIFIED |ANSWER✔✔-DNTP |synthesis
Allopurinol |- |VERIFIED |ANSWER✔✔-A |competitive |inhibitor |of |xanthine |oxidase. |Treats |gout
HGPRT |- |VERIFIED |ANSWER✔✔-Salvages |the |purine
Lesch |- |Nyhan |Syndrome |- |VERIFIED |ANSWER✔✔-HGPRT |deficiency |
Causes |arthritis |due |to |accumulation |of |Uric |acid, |retardation, |and |neurological |symptoms
Orotate |- |VERIFIED |ANSWER✔✔-Base |we |make |CUT |from
CPS |II |- |VERIFIED |ANSWER✔✔-Committed |step |in |pyrimidine |synthesis
UDP |and |UTP |inhibit |- |VERIFIED |ANSWER✔✔-Pyrimidine |syntheiss
correct answers
Purines |are |made |up |of |the |following |- |VERIFIED |ANSWER✔✔-Aspartic |Acid |(N1), |N10 |Formyl |THF |
(C2,8),glutamine |(N3,9), |glycine |(n7), |Co2 |(c6)
ADP |and |GDP |slow |down |the |rate |of |making |- |VERIFIED |ANSWER✔✔-PRPP
Rate |limiting |substance |in |purine |synthesis |- |VERIFIED |ANSWER✔✔-PRPP
Rate |limiting |enzyme |- |VERIFIED |ANSWER✔✔-Glutamine |phosphoribosyle |pyrophosphate |amido |
transferase
Glutamine |Phosphoribosyle |pyrophosphate |amido |transferase |is |inhibited |by |- |VERIFIED |ANSWER✔✔-
AMP,ADP,ATP |( |at |A |site) |GMP, |GDP, |GTP |( |at |g |site) |and |Azaserine
Nucleotide |- |VERIFIED |ANSWER✔✔-Phosphorylated |
Pentose
Nitrogenous |base
Nucleoside |- |VERIFIED |ANSWER✔✔-Pentose |
Nitrogenous |base
IMP |is |located |- |VERIFIED |ANSWER✔✔-Brain |and |liver
The |base |in |IMP |is |- |VERIFIED |ANSWER✔✔-Hypoxanthine
IMP |dehydrogenase |is |inhibited |by |- |VERIFIED |ANSWER✔✔-GMP
, Adenylosuccinate |synthetase |is |inhibited |by |- |VERIFIED |ANSWER✔✔-AMP
Adenylate |kinase |- |VERIFIED |ANSWER✔✔-AMP |+ |ATP |---> |GDP+ADP
Guanylate |Kinase |- |VERIFIED |ANSWER✔✔-GMP+ATP--> |GDP |+ |ADP
Nucleoside |diphosphate |kinase |- |VERIFIED |ANSWER✔✔-NDP+ATP--> |ADP |+ |NTP
ATP |and |GTP |are |used |for |- |VERIFIED |ANSWER✔✔-RNA |synthesis |( |transcription) |and |energy |transfers
|reactions
Nucleotides |break |- |VERIFIED |ANSWER✔✔-Phosphates
PNP |breaks |off |- |VERIFIED |ANSWER✔✔-Sugars
DATP |inhibits |- |VERIFIED |ANSWER✔✔-DNTP |synthesis
Allopurinol |- |VERIFIED |ANSWER✔✔-A |competitive |inhibitor |of |xanthine |oxidase. |Treats |gout
HGPRT |- |VERIFIED |ANSWER✔✔-Salvages |the |purine
Lesch |- |Nyhan |Syndrome |- |VERIFIED |ANSWER✔✔-HGPRT |deficiency |
Causes |arthritis |due |to |accumulation |of |Uric |acid, |retardation, |and |neurological |symptoms
Orotate |- |VERIFIED |ANSWER✔✔-Base |we |make |CUT |from
CPS |II |- |VERIFIED |ANSWER✔✔-Committed |step |in |pyrimidine |synthesis
UDP |and |UTP |inhibit |- |VERIFIED |ANSWER✔✔-Pyrimidine |syntheiss
