NURS6630 ///NURS 6630
PSYCHOPHARMACOLOGY MIDTERM
EXAM 2 VERSIONS ACTUAL MIDTERM
EXAM SUMMER QRT| MOST RECENT
WALDEN UNIVERSITY|AGRADED
/. Serotonin regulates - Answer-Mood, emotion, feeding, and reproductive behavior
/.This class of antidepressants binds to presynaptic SERT and inhibits them from
reuptake of serotonin to increase levels in the synaptic cleft to bind with postsysnaptic
5HT2 receptors - Answer-SSRIs
/.First line therapy for MDD due to milder side effect profiles - Answer-SSRIs
/.Six Common SSRIs - Answer-citalopram, escitalopram, fluoxetine, fluvoxamine,
sertraline, paroxetine
/.Onset of therapeutic benefit from SSRIs - Answer-4-6 weeks
/.In addition to MDD, SSRIs also treat - Answer-Chronic Anxiety, PTSD, OCD, and
eating disorders (bulimia)
/.Five Common side effects of SSRIs include - Answer-Anxiety, insomnia, GI distress,
sexual dysfunction (ED), SIADH
/.Severe side effect of SSRIs in children/adolescents under age 25 years old - Answer-
suicidal ideation
/.Life threatening adverse effect of SSRIs, especially when used in combination with
other serotonergic drugs (SNRIs, TCAs, MAOIs, etc.) - Answer-Serotonin Syndrome
/.Excess accumulation of serotonin resulting in overstimulation of the nervous system -
Answer-Serotonin Syndrome
/.Seven symptoms of Serotonin Syndrome - Answer-Flushing, hyperthermia, agitation,
muscle rigidity, seizure, coma, HYPERreflexia
, /.The treatment for serotonin syndrome - Answer-Cyproheptadine (5-HT2 receptor
antagonist)
/.Cyproheptadine treats serotonin syndrome by - Answer-blocking 5-HT2 receptors
(serotonin antagonist)
/.When SSRIs or SNRIs are stopped abruptly, common symptoms of withdrawal include
- Answer-Irritability, headaches, and insomnia
/.Medicine specific side effect of citalopram - Answer-Prolonged QT interval
(normal=0.4.-0.44 seconds)
/.This SSRI is pregnancy category D due to associations with congenital heart defects -
Answer-Paroxetine
/.All SSRIs but paroxetine (D) are pregnancy category - Answer-C
/.Three SSRIs that are inhibitors of Cytochrome P450 enzymes - Answer-fluoxetine,
fluvoxamine, and paroxetine
/.Five common SNRIs include - Answer-duloxetine, venlafaxine, desvenlafaxine,
milnacipran, levomilnacipran
/.This antidepressant class of medications works by binding to presynaptic SERT and
NET to inhibit them from reuptake of serotonin and norepinephrine to increase their
levels in the synaptic cleft - Answer-SNRIs
/.In addition to MDD SNRIs treat - Answer-Anxiety and neuropathic pain (peripheral
neuropathy)
/.Medication specific indications of duloxetine: - Answer-urinary incontinence and
Fibromyalgia
/.Medication specific indications of venlafaxine: - Answer-social anxiety, panic disorders,
PTSD, OCD, postmenopausal hot flashes
/.Six common side effects of SNRIs include: - Answer-Insomnia, nausea, sexual
dysfunction, hypertension, sweating, headaches
/.Severe side effect of SNRIs in children/adolescents under age 25 years old: - Answer-
suicidal ideation
/.Life threatening adverse effect of SNRIs, especially when used in combination with
other serotonergic drugs: - Answer-Serotonin Syndrome
/.This SNRI is an inhibitor of Cytochrome P450 enzymes: - Answer-venlafaxine
PSYCHOPHARMACOLOGY MIDTERM
EXAM 2 VERSIONS ACTUAL MIDTERM
EXAM SUMMER QRT| MOST RECENT
WALDEN UNIVERSITY|AGRADED
/. Serotonin regulates - Answer-Mood, emotion, feeding, and reproductive behavior
/.This class of antidepressants binds to presynaptic SERT and inhibits them from
reuptake of serotonin to increase levels in the synaptic cleft to bind with postsysnaptic
5HT2 receptors - Answer-SSRIs
/.First line therapy for MDD due to milder side effect profiles - Answer-SSRIs
/.Six Common SSRIs - Answer-citalopram, escitalopram, fluoxetine, fluvoxamine,
sertraline, paroxetine
/.Onset of therapeutic benefit from SSRIs - Answer-4-6 weeks
/.In addition to MDD, SSRIs also treat - Answer-Chronic Anxiety, PTSD, OCD, and
eating disorders (bulimia)
/.Five Common side effects of SSRIs include - Answer-Anxiety, insomnia, GI distress,
sexual dysfunction (ED), SIADH
/.Severe side effect of SSRIs in children/adolescents under age 25 years old - Answer-
suicidal ideation
/.Life threatening adverse effect of SSRIs, especially when used in combination with
other serotonergic drugs (SNRIs, TCAs, MAOIs, etc.) - Answer-Serotonin Syndrome
/.Excess accumulation of serotonin resulting in overstimulation of the nervous system -
Answer-Serotonin Syndrome
/.Seven symptoms of Serotonin Syndrome - Answer-Flushing, hyperthermia, agitation,
muscle rigidity, seizure, coma, HYPERreflexia
, /.The treatment for serotonin syndrome - Answer-Cyproheptadine (5-HT2 receptor
antagonist)
/.Cyproheptadine treats serotonin syndrome by - Answer-blocking 5-HT2 receptors
(serotonin antagonist)
/.When SSRIs or SNRIs are stopped abruptly, common symptoms of withdrawal include
- Answer-Irritability, headaches, and insomnia
/.Medicine specific side effect of citalopram - Answer-Prolonged QT interval
(normal=0.4.-0.44 seconds)
/.This SSRI is pregnancy category D due to associations with congenital heart defects -
Answer-Paroxetine
/.All SSRIs but paroxetine (D) are pregnancy category - Answer-C
/.Three SSRIs that are inhibitors of Cytochrome P450 enzymes - Answer-fluoxetine,
fluvoxamine, and paroxetine
/.Five common SNRIs include - Answer-duloxetine, venlafaxine, desvenlafaxine,
milnacipran, levomilnacipran
/.This antidepressant class of medications works by binding to presynaptic SERT and
NET to inhibit them from reuptake of serotonin and norepinephrine to increase their
levels in the synaptic cleft - Answer-SNRIs
/.In addition to MDD SNRIs treat - Answer-Anxiety and neuropathic pain (peripheral
neuropathy)
/.Medication specific indications of duloxetine: - Answer-urinary incontinence and
Fibromyalgia
/.Medication specific indications of venlafaxine: - Answer-social anxiety, panic disorders,
PTSD, OCD, postmenopausal hot flashes
/.Six common side effects of SNRIs include: - Answer-Insomnia, nausea, sexual
dysfunction, hypertension, sweating, headaches
/.Severe side effect of SNRIs in children/adolescents under age 25 years old: - Answer-
suicidal ideation
/.Life threatening adverse effect of SNRIs, especially when used in combination with
other serotonergic drugs: - Answer-Serotonin Syndrome
/.This SNRI is an inhibitor of Cytochrome P450 enzymes: - Answer-venlafaxine
