USMLE Step 1 Rapid Review 2025/2026
Exam Questions and Answers 100%
Guaranteed Success | Already Rated A+
Abdominal pain, ascites, hepatomegaly, (also high D dimer, CHF without
JVD) - 🧠 ANSWER ✔✔Budd-Chiari syndrome
Achilles tendon xanthoma - 🧠 ANSWER ✔✔Familial hypercholesterolemia
Adrenal hemorrhage, hypotension, DIC - 🧠 ANSWER ✔✔Waterhouse-
Friderichsen syndrome (meningococcemia)
Arachnodactyly, lens dislocation, aortic dissection, hyperflexible joints - 🧠
ANSWER ✔✔Marfan's (fibrillin defect)
Athlete with polycythemia - 🧠 ANSWER ✔✔Erythropoietin injection
Back pain, fever, night sweats, weight loss - 🧠 ANSWER ✔✔Pott's (TB to
the vertebrae)
Bilateral hilar adenopathy, uveitis - 🧠 ANSWER ✔✔Sarcoid
Blue sclera - 🧠 ANSWER ✔✔Osteogenesis imperfecta
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STATEMENT. ALL RIGHTS RESERVED
,Bluish line on gingiva - 🧠 ANSWER ✔✔Burton's line - lead poisoning
Bone pain, bone enlargement, arthritis, (also increased hat size, fracture,
increased alk phos) - 🧠 ANSWER ✔✔Paget's
Bounding pulses, diastolic hear murmur, head bobbing - 🧠 ANSWER
✔✔Aortic regurg
Café-au-lait spots, Lisch nodules - 🧠 ANSWER ✔✔NF (1 = optic glimoas
and pheo, 2 = acoustic Schwannomas)
Café-au-lait spots, polyostotic fibrous dysplasia, precocious puberty - 🧠
ANSWER ✔✔McCune-Albright syndome (G protein problem)
Calf pseudohypertrophy - 🧠 ANSWER ✔✔Duchenne's muscular dystrophy
Cherry-red spot on macula - 🧠 ANSWER ✔✔Tay-Sachs, Niemann-Pick,
central retinal artery occlusion
Chest pain, pericardial effusion/friction rub, persistent fever following MI - 🧠
ANSWER ✔✔Dressler's (autoimmune post-MI)
Child uses arms to stand up from squat - 🧠 ANSWER ✔✔Gower's sign
(Duchenne's)
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STATEMENT. ALL RIGHTS RESERVED
, Child with fever develops red rash on face that spreads to body - 🧠
ANSWER ✔✔Slapped cheek - B19
Chorea, dementia, caudate degeneration - 🧠 ANSWER ✔✔Huntington's
Chronic exercise intolerance with myalgia, fatigue, painful cramps - 🧠
ANSWER ✔✔McArdle's (muscle phosphorylase deficiency)
Cold intolerance - 🧠 ANSWER ✔✔Hypothyroidism
Conjugate lateral gaze palsy, horizontal diplopia - 🧠 ANSWER
✔✔Internuclear ophthalmoplegia (MS or stroke)
Continuous machinery heart murmur - 🧠 ANSWER ✔✔PDA
Cutaneous/dermal edema due to CT expansion - 🧠 ANSWER
✔✔Myxedema
Dark purple skin / mouth nodules - 🧠 ANSWER ✔✔Kaposi's sarcoma
Deep, labored breathing / hyperventilation - 🧠 ANSWER ✔✔Kussmaul
breathing, DKA
Dermatitis, dementia, diarrhea - 🧠 ANSWER ✔✔Pellagra (B3 / niacin
deficiency)
COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
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STATEMENT. ALL RIGHTS RESERVED
Exam Questions and Answers 100%
Guaranteed Success | Already Rated A+
Abdominal pain, ascites, hepatomegaly, (also high D dimer, CHF without
JVD) - 🧠 ANSWER ✔✔Budd-Chiari syndrome
Achilles tendon xanthoma - 🧠 ANSWER ✔✔Familial hypercholesterolemia
Adrenal hemorrhage, hypotension, DIC - 🧠 ANSWER ✔✔Waterhouse-
Friderichsen syndrome (meningococcemia)
Arachnodactyly, lens dislocation, aortic dissection, hyperflexible joints - 🧠
ANSWER ✔✔Marfan's (fibrillin defect)
Athlete with polycythemia - 🧠 ANSWER ✔✔Erythropoietin injection
Back pain, fever, night sweats, weight loss - 🧠 ANSWER ✔✔Pott's (TB to
the vertebrae)
Bilateral hilar adenopathy, uveitis - 🧠 ANSWER ✔✔Sarcoid
Blue sclera - 🧠 ANSWER ✔✔Osteogenesis imperfecta
COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
1
STATEMENT. ALL RIGHTS RESERVED
,Bluish line on gingiva - 🧠 ANSWER ✔✔Burton's line - lead poisoning
Bone pain, bone enlargement, arthritis, (also increased hat size, fracture,
increased alk phos) - 🧠 ANSWER ✔✔Paget's
Bounding pulses, diastolic hear murmur, head bobbing - 🧠 ANSWER
✔✔Aortic regurg
Café-au-lait spots, Lisch nodules - 🧠 ANSWER ✔✔NF (1 = optic glimoas
and pheo, 2 = acoustic Schwannomas)
Café-au-lait spots, polyostotic fibrous dysplasia, precocious puberty - 🧠
ANSWER ✔✔McCune-Albright syndome (G protein problem)
Calf pseudohypertrophy - 🧠 ANSWER ✔✔Duchenne's muscular dystrophy
Cherry-red spot on macula - 🧠 ANSWER ✔✔Tay-Sachs, Niemann-Pick,
central retinal artery occlusion
Chest pain, pericardial effusion/friction rub, persistent fever following MI - 🧠
ANSWER ✔✔Dressler's (autoimmune post-MI)
Child uses arms to stand up from squat - 🧠 ANSWER ✔✔Gower's sign
(Duchenne's)
COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
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STATEMENT. ALL RIGHTS RESERVED
, Child with fever develops red rash on face that spreads to body - 🧠
ANSWER ✔✔Slapped cheek - B19
Chorea, dementia, caudate degeneration - 🧠 ANSWER ✔✔Huntington's
Chronic exercise intolerance with myalgia, fatigue, painful cramps - 🧠
ANSWER ✔✔McArdle's (muscle phosphorylase deficiency)
Cold intolerance - 🧠 ANSWER ✔✔Hypothyroidism
Conjugate lateral gaze palsy, horizontal diplopia - 🧠 ANSWER
✔✔Internuclear ophthalmoplegia (MS or stroke)
Continuous machinery heart murmur - 🧠 ANSWER ✔✔PDA
Cutaneous/dermal edema due to CT expansion - 🧠 ANSWER
✔✔Myxedema
Dark purple skin / mouth nodules - 🧠 ANSWER ✔✔Kaposi's sarcoma
Deep, labored breathing / hyperventilation - 🧠 ANSWER ✔✔Kussmaul
breathing, DKA
Dermatitis, dementia, diarrhea - 🧠 ANSWER ✔✔Pellagra (B3 / niacin
deficiency)
COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER: 619652435. TERMS OF USE. PRIVACY
3
STATEMENT. ALL RIGHTS RESERVED
