Test bank for Tietz Fundamentals of Clinical Chemistry
f# f# f# f# f# f# f#
f# and Molecular Diagnostics,
f# f# f#
8th Edition by Nader Rifai, PhD
f# f# f# f# f# f#
Chapters 1 - 49
f# f# f# f#
,Tietz f#Fundamentals f#of f#Clinical f#Chemistry f#and f#Molecular f#Diagnostics f#8th f # Edition f#Test f#Bank
Table f#of f#contents:
I. f#Principles f#Of f#Laboratory f#Medicine
Chapter f#1. f#Clinical f#Chemistry, f#Molecular f#Diagnostics, f#and f#Laboratory f#Medicine
Chapter f#2. f#Selection f#and f#Analytical f#Evaluation f#of f#Methods f#— f#With f#Statistical
f#Techniques
Chapter f#3. f#Clinical f#Evaluation f#of f#Methods
Chapter f#4. f#Evidence-Based f#Laboratory f#Medicine
Chapter f#5. f#Establishment f#and f#Use f#of f#Reference f#Values
Chapter f#6. f#Specimen f#Collection, f#Processing, f#and f#Other f#Preanalytical f#Variables
Chapter f#7. f#Quality f#Management
II. f#Analytical f#Techniques f#And f#Instrumentation
Chapter f#8. f#Principles f#of f#Basic f#Techniques f#and f#Laboratory f#Safety
Chapter f#9. f#Optical f#Techniques
Chapter f#10. f#Electrochemistry f#and f#Chemical f#Sensors
Chapter f#11. f#Electrophoresis
Chapter f#12. f#Chromatography
Chapter f#13. f#Mass f#Spectrometry
Chapter f#14. f#Enzyme f#and f#Rate f#Analyses
Chapter f#15. f#Immunochemical f#Techniques
Chapter f#16 f#Automation
Chapter f#17. f#Point-of-Care f#Instrumentation
III. f # Analytes
Chapter f#18. f#Amino f#Acids, f#Peptides, f#and f#Proteins
Chapter f#19. f#Serum f#Enzymes
Chapter f#20. f#Tumor f#Markers f#and f#Cancer f#Genes
Chapter f#21. f#Kidney f#Function f#Tests f#— f#Creatinine, f#GFR, f#Urea, f#and f#Uric f#Acid
Chapter f#22. f#Carbohydrates
Chapter f#23. f#Lipids, f#Lipoproteins, f#Apolipoproteins, f#and f#Other f#Cardiac f#Risk f#Factors
Chapter f#24. f#Electrolytes f#and f#Blood f#Gases
Chapter f#25. f#Hormones
Chapter f#26. f # Catecholamines f#and f#Serotonin
Chapter f#27. f # Vitamins, f#Trace f#Elements, f#Nutritional f#Assessment
Chapter f#28. f#Hemoglobin, f#Iron, f#and f#Bilirubin
Chapter f#29. f#Porphyrins f#and f#Porphyrias
Chapter f#30. f#Therapeutic f#Drugs f#and f#Their f#Management
Chapter f#31. f#Clinical f#Toxicology
Chapter f#32. f # Toxic f#Metals
IV. f # Pathophysiology
Chapter f#33. f#Diabetes
,Chapter f#34. f # Cardiovascular f#Disease
Chapter f#35. f#Kidney f#Disease
Chapter f#36. f # Physiology f#and f#Disorders f#of f#Water, f#Electrolyte, f#and f#Acid-Base
f#Metabolism
Chapter f#37. f# f#Liver f#Disease
Chapter f#38. f # Gastrointestinal f#and f#Pancreatic f#Diseases
Chapter f#39. f# f#Disorders f#of f#Bone f#and f#Mineral f#Metabolism
Chapter f#40. f# f#Disorders f#of f#the f#Pituitary f#Gland
Chapter f#41. f # Disorders f#of f#the f#Adrenal f#Cortex
Chapter f#42. f # Thyroid f#Disorders
Chapter f#43. f # Reproduction-Related f#Disorders
Chapter f#44. f# f#Pregnancy f#and f#Prenatal f#Testing
Chapter f#45. f # Newborn f#Screening f#and f#Inborn f#Errors f#of f#Metabolism
Chapter f#46. f#Pharmacogenetics
V. f # Molecular f#Diagnostics
Chapter f#47. f#Principles f#of f#Molecular f#Biology
Chapter f#48. f#Nucleic f#Acid f#Techniques f#and f#Applications
Chapter f#49. f#Genomes f#and f#Nucleic f#Acid f#Alterations
, Chapter f#01: f#Clinical f#Chemistry, f#Molecular f#Diagnostics, f#and f#Laboratory
f#Medicine f#Test#B
f ank
MULTIPLE f#CHOICE
1. An f#individual f#working f#in f#a f#clinical f#chemistry f#laboratory f#is f#married f#to f#a f#sales
f#representative f#who f#works f#for f#a f#company f#that f#sells f#chemistry f#laboratory f#supplies.
f#When f#the f#laboratory f#manager f#requests f#a f#list f#of f#needed f#supplies, f#cost f#of f#supplies,
f#and f#vendors, f#this f#individual f#only#frecommends f#the f#spouse’s f#company f#as f#the f#vendor.
f#This f#is f#considered f#to f#be f#a(n):
a. accounting f#issue.
b. possible f#conflict f#of f#interest.
c. maintenance f#of f#confidentiality f#issue.
d. problem f#with f#resource f#allocation.
ANS: f # B
Concern f#has f#been f#raised f#over f#the f#interrelationships f#between f#practitioners f#in f#the
f#medical f#field#a
f nd f#commercial f#suppliers f#of f#drugs, f#devices, f#equipment, f#etc., f#to f#the
f#medical f# profession.
Similarly, f#relationships f#have f#been f#scrutinized f#between f#clinical f#laboratorians f#and
f#manufacturers f#and f#providers f#of f#diagnostic f#equipment f#and f#supplies. f#These f#concerns
f#led f#the f#National f#Institutes f#of f#Health f#(NIH) f#in f#1995 f#to f#require f#official f#institutional
f#review f#of f#financial f#disclosure f#by f#researchers f#and f#management f#of f#situations f#in f#which
f#disclosure f#indicates f#potential#fconflicts f#of f#interest.
DIF: 1 REF: f# f# f#Page f#4-5 OBJ: f # 6 f#| f#7
2. A f#patient f#visits f#her f#physician f#stating f#that f#her f#prescribed f#painkiller f#is f#not f#working
f#to f#reduce f#the f#pain f#following f#her f#recent f#surgery. f#A f#friend f#of f#the f#patient f#claims
f#that f#the f#same f#painkiller#“
f worked f#wonders” f#to f#reduce f#her f#pain f#after f#the f#same
f#surgery. f#The f#physician f#states f#that f#the f#difference f#in f#the f#effect f#of f#the f#drug f#might
f#be f#caused f#by , f#which f#is f#studied f#in
f#pharmacogenetics.
a. epidemiology
b. an f#inherited f#disease
c. a f#conflict f#of f#interest
d. a f#genetic f#variation f#in f#drug-metabolizing f#enzymes
ANS: f # D
Pharmacogenetics f#is f#the f#study f#of f#the f#genetic f#variation f#of f#drug f#metabolism
f#between#findividuals.
DIF: 1 REF: f# f# f# Page f#3 OBJ: f # 1
3. John f#works f#in f#a f#molecular f#diagnostics f#laboratory f#and f#receives f#a f#blood f#sample
f#that f#has f#the f#name f#of f#a f#close f#friend f#printed f#on f#the f#bar-coded f#label. f#The f#genetic
f#test f#that f#is f#ordered f#on f#the#f
f riend’s f#sample f#would f#provide f#diagnostic f#information
f#about f#a f#disorder f#that f#has f#a f#poor f#prognosis, f#and f#the f#test f#is f#usually f#performed f#by
f#John. f#He f#asks f#a f#fellow f#employee f#to f#analyze#fthe f#sample f#for f#him f#and f#not f#divulge
f#the f#results. f#This f#ethical f#issue f#concerns:
a. confidentiality f#of f#patient f#genetic f#and f#medical f#information.
b. a f#conflict f#of f#interest.
c. resource f#allocation.
d. diagnostic f#accuracy.
f# f# f# f# f# f# f#
f# and Molecular Diagnostics,
f# f# f#
8th Edition by Nader Rifai, PhD
f# f# f# f# f# f#
Chapters 1 - 49
f# f# f# f#
,Tietz f#Fundamentals f#of f#Clinical f#Chemistry f#and f#Molecular f#Diagnostics f#8th f # Edition f#Test f#Bank
Table f#of f#contents:
I. f#Principles f#Of f#Laboratory f#Medicine
Chapter f#1. f#Clinical f#Chemistry, f#Molecular f#Diagnostics, f#and f#Laboratory f#Medicine
Chapter f#2. f#Selection f#and f#Analytical f#Evaluation f#of f#Methods f#— f#With f#Statistical
f#Techniques
Chapter f#3. f#Clinical f#Evaluation f#of f#Methods
Chapter f#4. f#Evidence-Based f#Laboratory f#Medicine
Chapter f#5. f#Establishment f#and f#Use f#of f#Reference f#Values
Chapter f#6. f#Specimen f#Collection, f#Processing, f#and f#Other f#Preanalytical f#Variables
Chapter f#7. f#Quality f#Management
II. f#Analytical f#Techniques f#And f#Instrumentation
Chapter f#8. f#Principles f#of f#Basic f#Techniques f#and f#Laboratory f#Safety
Chapter f#9. f#Optical f#Techniques
Chapter f#10. f#Electrochemistry f#and f#Chemical f#Sensors
Chapter f#11. f#Electrophoresis
Chapter f#12. f#Chromatography
Chapter f#13. f#Mass f#Spectrometry
Chapter f#14. f#Enzyme f#and f#Rate f#Analyses
Chapter f#15. f#Immunochemical f#Techniques
Chapter f#16 f#Automation
Chapter f#17. f#Point-of-Care f#Instrumentation
III. f # Analytes
Chapter f#18. f#Amino f#Acids, f#Peptides, f#and f#Proteins
Chapter f#19. f#Serum f#Enzymes
Chapter f#20. f#Tumor f#Markers f#and f#Cancer f#Genes
Chapter f#21. f#Kidney f#Function f#Tests f#— f#Creatinine, f#GFR, f#Urea, f#and f#Uric f#Acid
Chapter f#22. f#Carbohydrates
Chapter f#23. f#Lipids, f#Lipoproteins, f#Apolipoproteins, f#and f#Other f#Cardiac f#Risk f#Factors
Chapter f#24. f#Electrolytes f#and f#Blood f#Gases
Chapter f#25. f#Hormones
Chapter f#26. f # Catecholamines f#and f#Serotonin
Chapter f#27. f # Vitamins, f#Trace f#Elements, f#Nutritional f#Assessment
Chapter f#28. f#Hemoglobin, f#Iron, f#and f#Bilirubin
Chapter f#29. f#Porphyrins f#and f#Porphyrias
Chapter f#30. f#Therapeutic f#Drugs f#and f#Their f#Management
Chapter f#31. f#Clinical f#Toxicology
Chapter f#32. f # Toxic f#Metals
IV. f # Pathophysiology
Chapter f#33. f#Diabetes
,Chapter f#34. f # Cardiovascular f#Disease
Chapter f#35. f#Kidney f#Disease
Chapter f#36. f # Physiology f#and f#Disorders f#of f#Water, f#Electrolyte, f#and f#Acid-Base
f#Metabolism
Chapter f#37. f# f#Liver f#Disease
Chapter f#38. f # Gastrointestinal f#and f#Pancreatic f#Diseases
Chapter f#39. f# f#Disorders f#of f#Bone f#and f#Mineral f#Metabolism
Chapter f#40. f# f#Disorders f#of f#the f#Pituitary f#Gland
Chapter f#41. f # Disorders f#of f#the f#Adrenal f#Cortex
Chapter f#42. f # Thyroid f#Disorders
Chapter f#43. f # Reproduction-Related f#Disorders
Chapter f#44. f# f#Pregnancy f#and f#Prenatal f#Testing
Chapter f#45. f # Newborn f#Screening f#and f#Inborn f#Errors f#of f#Metabolism
Chapter f#46. f#Pharmacogenetics
V. f # Molecular f#Diagnostics
Chapter f#47. f#Principles f#of f#Molecular f#Biology
Chapter f#48. f#Nucleic f#Acid f#Techniques f#and f#Applications
Chapter f#49. f#Genomes f#and f#Nucleic f#Acid f#Alterations
, Chapter f#01: f#Clinical f#Chemistry, f#Molecular f#Diagnostics, f#and f#Laboratory
f#Medicine f#Test#B
f ank
MULTIPLE f#CHOICE
1. An f#individual f#working f#in f#a f#clinical f#chemistry f#laboratory f#is f#married f#to f#a f#sales
f#representative f#who f#works f#for f#a f#company f#that f#sells f#chemistry f#laboratory f#supplies.
f#When f#the f#laboratory f#manager f#requests f#a f#list f#of f#needed f#supplies, f#cost f#of f#supplies,
f#and f#vendors, f#this f#individual f#only#frecommends f#the f#spouse’s f#company f#as f#the f#vendor.
f#This f#is f#considered f#to f#be f#a(n):
a. accounting f#issue.
b. possible f#conflict f#of f#interest.
c. maintenance f#of f#confidentiality f#issue.
d. problem f#with f#resource f#allocation.
ANS: f # B
Concern f#has f#been f#raised f#over f#the f#interrelationships f#between f#practitioners f#in f#the
f#medical f#field#a
f nd f#commercial f#suppliers f#of f#drugs, f#devices, f#equipment, f#etc., f#to f#the
f#medical f# profession.
Similarly, f#relationships f#have f#been f#scrutinized f#between f#clinical f#laboratorians f#and
f#manufacturers f#and f#providers f#of f#diagnostic f#equipment f#and f#supplies. f#These f#concerns
f#led f#the f#National f#Institutes f#of f#Health f#(NIH) f#in f#1995 f#to f#require f#official f#institutional
f#review f#of f#financial f#disclosure f#by f#researchers f#and f#management f#of f#situations f#in f#which
f#disclosure f#indicates f#potential#fconflicts f#of f#interest.
DIF: 1 REF: f# f# f#Page f#4-5 OBJ: f # 6 f#| f#7
2. A f#patient f#visits f#her f#physician f#stating f#that f#her f#prescribed f#painkiller f#is f#not f#working
f#to f#reduce f#the f#pain f#following f#her f#recent f#surgery. f#A f#friend f#of f#the f#patient f#claims
f#that f#the f#same f#painkiller#“
f worked f#wonders” f#to f#reduce f#her f#pain f#after f#the f#same
f#surgery. f#The f#physician f#states f#that f#the f#difference f#in f#the f#effect f#of f#the f#drug f#might
f#be f#caused f#by , f#which f#is f#studied f#in
f#pharmacogenetics.
a. epidemiology
b. an f#inherited f#disease
c. a f#conflict f#of f#interest
d. a f#genetic f#variation f#in f#drug-metabolizing f#enzymes
ANS: f # D
Pharmacogenetics f#is f#the f#study f#of f#the f#genetic f#variation f#of f#drug f#metabolism
f#between#findividuals.
DIF: 1 REF: f# f# f# Page f#3 OBJ: f # 1
3. John f#works f#in f#a f#molecular f#diagnostics f#laboratory f#and f#receives f#a f#blood f#sample
f#that f#has f#the f#name f#of f#a f#close f#friend f#printed f#on f#the f#bar-coded f#label. f#The f#genetic
f#test f#that f#is f#ordered f#on f#the#f
f riend’s f#sample f#would f#provide f#diagnostic f#information
f#about f#a f#disorder f#that f#has f#a f#poor f#prognosis, f#and f#the f#test f#is f#usually f#performed f#by
f#John. f#He f#asks f#a f#fellow f#employee f#to f#analyze#fthe f#sample f#for f#him f#and f#not f#divulge
f#the f#results. f#This f#ethical f#issue f#concerns:
a. confidentiality f#of f#patient f#genetic f#and f#medical f#information.
b. a f#conflict f#of f#interest.
c. resource f#allocation.
d. diagnostic f#accuracy.
