HESI PHARMACOLOGY COMPREHENSIVE REVIEW EXAM 2025 QUESTIONS AND
ANSWERS|WELL STRUCTURED| A+ GRADED+
A client with mild parkinsonism is started on oral amantadine
(Symmetrel). Which statement accurately describes the action of
this medication?
A.
Viral organisms that provide the underlying pathophysiology for
parkinsonism are eliminated.
Dopamine in the central nervous system is increased.
B.
Acetylcholine in the myoneural junction is enhanced.
C.
Dopamine in the central nervous system is increased.
D.
Norepinephrine release is reduced within the peripheral system
as the final step in dopamine uptake.
The nurse is reviewing a client's laboratory results before a proce-
dure in which a neuromuscular blocking agent is a standing order.
Which finding should the nurse report to the health care provider?
A.
Hypokalemia
Hypokalemia
B.
Hyponatremia
C.
Hypercalcemia
D.
Hypomagnesemia
A male client asks the nurse why condoms should not be lubri-
cated with the spermicide nonoxynol-9. Which response is best
for the nurse to provide?
A.
The risk of female infertility and spontaneous abortion is linked
with nonoxynol-9.
B. Nonoxynol-9 provides no protection from STDs and has been
Partners can develop intermittent interstitial cystitis if the spermi- linked to the transmission of HIV.
cide is used after the expiration date.
C.
The spermicide decreases the amount of vaginal and penile sen-
sitivity for up to 8 to 12 hours.
D.
Nonoxynol-9 provides no protection from STDs and has been
linked to the transmission of HIV.
The nurse is assessing a stuporous client in the emergency
department who is suspected of overdosing with opioids. Which
agent should the nurse prepare to administer if the client becomes
comatose?
A.
Naloxone hydrochloride Naloxone hydrochloride (Narcan)
B.
Atropine sulfate
C.
Vitamin K
D.
Flumazenil
A 2-month-old infant is scheduled to receive the first DPT im-
munization. What is the preferred injection site to administer this
immunization?
Vastus lateralis
A.
Dorsal gluteal
, HESI PHARMACOLOGY COMPREHENSIVE REVIEW EXAM 2025 QUESTIONS AND
ANSWERS|WELL STRUCTURED| A+ GRADED+
B.
Vastus lateralis
C.
Ventral gluteal
D.
Deltoid
A psychiatric client is discharged from the hospital with a prescrip-
tion for haloperidol (Haldol). Which instruction should the nurse
include in the discharge teaching plan for this client?
A.
Take with antacids to reduce gastrointestinal irritation.
Use sunglasses and sunscreen when outdoors.
B.
Use sunglasses and sunscreen when outdoors.
C.
Eat foods low in fiber and salt.
D.
Count the pulse before each dose.
A client with metastatic cancer reports severe continuous pain.
Which route of administration should the nurse use to provide the
most effective continuous analgesia?
A.
Oral
Transdermal
B.
Intravenous
C.
Transdermal
D.
Intramuscular
A primigravida at 34 weeks of gestation is admitted to labor and
delivery in preterm labor. She is started on a terbutaline sulfate
(Brethine) continuous IV infusion via pump. This therapy is inef-
fective, and the baby is delivered vaginally. For which complication
should the nurse monitor in this infant during the first few hours
after delivery?
C.
A.
Hypoglycemia
Hypokalemia
B.
Hypermagnesia
C.
Hypoglycemia
D.
Hypernatremia
A client who is hypertensive receives a prescription for hy-
drochlorothiazide (HCTZ). When teaching about the side effects
of this drug, which symptoms are most important for the nurse to
instruct the client to report?
A.
Fatigue and muscle weakness Fatigue and muscle weakness
B.
Anxiety and heart palpitations
C.
Abdominal cramping and diarrhea
D.
Confusion and personality changes
Methylphenidate HCl (Concerta) is prescribed for daily admin-
istration to a 10-year-old child with attention deficit-hyperactivity
disorder (ADHD). In preparing a teaching plan for the parents of
, HESI PHARMACOLOGY COMPREHENSIVE REVIEW EXAM 2025 QUESTIONS AND
ANSWERS|WELL STRUCTURED| A+ GRADED+
this child newly diagnosed with ADHD, which instruction is most Administer the medication in the morning before the child goes to
important for the nurse to provide to the parents? school.
Prior to administering a scheduled dose of digoxin (Lanoxin), the
nurse reviews the client's current serum digoxin level, which is 1.3
ng/dL. Which action should the nurse implement?
A.
Administer Digibind to counteract the toxicity.
B. Give the dose of digoxin if the client's heart rate is within a safe
Withhold the drug and notify the health care provider immediately. range.
C.
Withhold the dose and notify the health care provider during
rounds that the dose was held.
D.
Give the dose of digoxin if the client's heart rate is within a safe
range.
The health care provider has prescribed a low-molecular-weight
heparin, enoxaparin (Lovenox) prefilled syringe, 30 mg/0.3 mL
IV every 12 hours, for a client following hip replacement. Prior to Contact the health care provider to clarify the prescription.
administering the first dose, which intervention is most important
for the nurse to implement?
In administering the antiinfective agent chloramphenicol
(Chloromycetin) IV to a client with bacterial meningitis, the nurse
observes the client closely for signs of bone marrow depression.
Which laboratory data would be most important for the nurse to
monitor?
A.
Platelet count
Platelet count
B.
Blood urea nitrogen level
C.
Culture and sensitivity
D.
Serum calcium level
A client with viral influenza is receiving vitamin C, 1000 mg PO
daily, and acetaminophen elixir, 650 mg PO every 4 hours PRN.
The nurse calls the health care provider to report that the client Decrease the dose of vitamin C.
has developed diarrhea. Which change in prescriptions should the
nurse anticipate?
A client who is receiving chlorpromazine HCl (Thorazine) to con-
trol his psychotic behavior also has a prescription for benztropine
(Cogentin). When teaching the client and/or significant others
about these medications, what should the nurse explain about the
use of benztropine (Cogentin) in the treatment plan for this client?
A. The benztropine (Cogentin) is used to control extrapyramidal
This medication will reduce the side effect of urinary retention. symptoms.
B.
This drug potentiates the effect of chlorpromazine HCl.
C.
The benztropine is used to control extrapyramidal symptoms.
D.
The combined effect of these drugs will modify psychotic behavior
A female client with myasthenia gravis is taking a cholinesterase
inhibitor and asks the nurse what can be done to remedy her
fatigue and difficulty swallowing. What action should the nurse
implement?
A.
ANSWERS|WELL STRUCTURED| A+ GRADED+
A client with mild parkinsonism is started on oral amantadine
(Symmetrel). Which statement accurately describes the action of
this medication?
A.
Viral organisms that provide the underlying pathophysiology for
parkinsonism are eliminated.
Dopamine in the central nervous system is increased.
B.
Acetylcholine in the myoneural junction is enhanced.
C.
Dopamine in the central nervous system is increased.
D.
Norepinephrine release is reduced within the peripheral system
as the final step in dopamine uptake.
The nurse is reviewing a client's laboratory results before a proce-
dure in which a neuromuscular blocking agent is a standing order.
Which finding should the nurse report to the health care provider?
A.
Hypokalemia
Hypokalemia
B.
Hyponatremia
C.
Hypercalcemia
D.
Hypomagnesemia
A male client asks the nurse why condoms should not be lubri-
cated with the spermicide nonoxynol-9. Which response is best
for the nurse to provide?
A.
The risk of female infertility and spontaneous abortion is linked
with nonoxynol-9.
B. Nonoxynol-9 provides no protection from STDs and has been
Partners can develop intermittent interstitial cystitis if the spermi- linked to the transmission of HIV.
cide is used after the expiration date.
C.
The spermicide decreases the amount of vaginal and penile sen-
sitivity for up to 8 to 12 hours.
D.
Nonoxynol-9 provides no protection from STDs and has been
linked to the transmission of HIV.
The nurse is assessing a stuporous client in the emergency
department who is suspected of overdosing with opioids. Which
agent should the nurse prepare to administer if the client becomes
comatose?
A.
Naloxone hydrochloride Naloxone hydrochloride (Narcan)
B.
Atropine sulfate
C.
Vitamin K
D.
Flumazenil
A 2-month-old infant is scheduled to receive the first DPT im-
munization. What is the preferred injection site to administer this
immunization?
Vastus lateralis
A.
Dorsal gluteal
, HESI PHARMACOLOGY COMPREHENSIVE REVIEW EXAM 2025 QUESTIONS AND
ANSWERS|WELL STRUCTURED| A+ GRADED+
B.
Vastus lateralis
C.
Ventral gluteal
D.
Deltoid
A psychiatric client is discharged from the hospital with a prescrip-
tion for haloperidol (Haldol). Which instruction should the nurse
include in the discharge teaching plan for this client?
A.
Take with antacids to reduce gastrointestinal irritation.
Use sunglasses and sunscreen when outdoors.
B.
Use sunglasses and sunscreen when outdoors.
C.
Eat foods low in fiber and salt.
D.
Count the pulse before each dose.
A client with metastatic cancer reports severe continuous pain.
Which route of administration should the nurse use to provide the
most effective continuous analgesia?
A.
Oral
Transdermal
B.
Intravenous
C.
Transdermal
D.
Intramuscular
A primigravida at 34 weeks of gestation is admitted to labor and
delivery in preterm labor. She is started on a terbutaline sulfate
(Brethine) continuous IV infusion via pump. This therapy is inef-
fective, and the baby is delivered vaginally. For which complication
should the nurse monitor in this infant during the first few hours
after delivery?
C.
A.
Hypoglycemia
Hypokalemia
B.
Hypermagnesia
C.
Hypoglycemia
D.
Hypernatremia
A client who is hypertensive receives a prescription for hy-
drochlorothiazide (HCTZ). When teaching about the side effects
of this drug, which symptoms are most important for the nurse to
instruct the client to report?
A.
Fatigue and muscle weakness Fatigue and muscle weakness
B.
Anxiety and heart palpitations
C.
Abdominal cramping and diarrhea
D.
Confusion and personality changes
Methylphenidate HCl (Concerta) is prescribed for daily admin-
istration to a 10-year-old child with attention deficit-hyperactivity
disorder (ADHD). In preparing a teaching plan for the parents of
, HESI PHARMACOLOGY COMPREHENSIVE REVIEW EXAM 2025 QUESTIONS AND
ANSWERS|WELL STRUCTURED| A+ GRADED+
this child newly diagnosed with ADHD, which instruction is most Administer the medication in the morning before the child goes to
important for the nurse to provide to the parents? school.
Prior to administering a scheduled dose of digoxin (Lanoxin), the
nurse reviews the client's current serum digoxin level, which is 1.3
ng/dL. Which action should the nurse implement?
A.
Administer Digibind to counteract the toxicity.
B. Give the dose of digoxin if the client's heart rate is within a safe
Withhold the drug and notify the health care provider immediately. range.
C.
Withhold the dose and notify the health care provider during
rounds that the dose was held.
D.
Give the dose of digoxin if the client's heart rate is within a safe
range.
The health care provider has prescribed a low-molecular-weight
heparin, enoxaparin (Lovenox) prefilled syringe, 30 mg/0.3 mL
IV every 12 hours, for a client following hip replacement. Prior to Contact the health care provider to clarify the prescription.
administering the first dose, which intervention is most important
for the nurse to implement?
In administering the antiinfective agent chloramphenicol
(Chloromycetin) IV to a client with bacterial meningitis, the nurse
observes the client closely for signs of bone marrow depression.
Which laboratory data would be most important for the nurse to
monitor?
A.
Platelet count
Platelet count
B.
Blood urea nitrogen level
C.
Culture and sensitivity
D.
Serum calcium level
A client with viral influenza is receiving vitamin C, 1000 mg PO
daily, and acetaminophen elixir, 650 mg PO every 4 hours PRN.
The nurse calls the health care provider to report that the client Decrease the dose of vitamin C.
has developed diarrhea. Which change in prescriptions should the
nurse anticipate?
A client who is receiving chlorpromazine HCl (Thorazine) to con-
trol his psychotic behavior also has a prescription for benztropine
(Cogentin). When teaching the client and/or significant others
about these medications, what should the nurse explain about the
use of benztropine (Cogentin) in the treatment plan for this client?
A. The benztropine (Cogentin) is used to control extrapyramidal
This medication will reduce the side effect of urinary retention. symptoms.
B.
This drug potentiates the effect of chlorpromazine HCl.
C.
The benztropine is used to control extrapyramidal symptoms.
D.
The combined effect of these drugs will modify psychotic behavior
A female client with myasthenia gravis is taking a cholinesterase
inhibitor and asks the nurse what can be done to remedy her
fatigue and difficulty swallowing. What action should the nurse
implement?
A.
