HESI RN PHARMACOLOGY
V2 EXAM (3 Set Exams)
(NGN style Qs & Case studies)
Actual Qs & Ans to Pass the Exam
This hesi test contains:
passing score Guarantee
Each Exam has 55 Ques and Ans
Format Set of Multiple-choice
questions with incorporating Next Generation
NCLEX (NGN) and Case studies questions
Expert-Verified Explanations & Solutions
,Contents
HESI RN PHARMACOLOGY V2 EXAM ...................... 2
SET 1 ......................................................................... 2
HESI RN PHARMACOLOGY V2 EXAM .................... 37
SET 2 ....................................................................... 37
HESI RN PHARMACOLOGY V2 EXAM .................... 69
SET 3 ....................................................................... 69
HESI RN PHARMACOLOGY V2 EXAM
SET 1
────────────────────────────────────────────────────
1) The nurse is caring for a client who has taken atenolol for 2 years. The
healthcare provider recently changed the medica!on to enalapril to manage the
client’s blood pressure. Which instruc!on should the nurse provide the client
regarding the new medica!on?
A. Take the medica!on at bed!me.
B. Report presence of increased bruising.
, C. Check pulse before taking medica!on.
D. Rise slowly when ge+ng out of bed or chair.
Answer: D. Rise slowly when ge+ng out of bed or chair.
Expert-Verified Explana/on:
• Enalapril (ACE inhibitor) can cause vasodila!on and orthosta!c hypotension.
Teaching the client to stand up slowly helps prevent dizziness or falls.
• “Take at bed!me” (A) is some!mes used for nocturnal BP control, but the
priority is orthosta!c safety.
• “Report bruising” (B) is more relevant to an!coagulants.
• “Check pulse” (C) is more important with beta-blockers.
────────────────────────────────────────────────────
2) A female client calls the clinic and inquires about a possible reac!on a6er
taking amoxicillin for 5 days. She reports having vaginal discomfort, itching, and
white discharge. The nurse should discuss which ac!on with the client?
A. Discon!nue the an!bio!c because original symptoms have subsided.
B. Con!nue taking the medica!on un!l finished un!l the symptoms subside.
C. Consult with a healthcare provider about another treatment for this effect.
D. Use an over-the-counter (OTC) vaginal wash to flush out the secre!ons.
Answer: C. Consult with a healthcare provider about another treatment for this
effect.
,Expert-Verified Explana/on:
• Amoxicillin can disrupt normal flora, some!mes causing a yeast infec!on. The
an!bio!c course must be completed, but an an!fungal may be needed.
• Discon!nuing (A) risks incomplete treatment.
• Merely con!nuing without addressing the infec!on (B) misses the yeast
infec!on concern.
• OTC washes (D) do not fully treat fungal infec!on.
────────────────────────────────────────────────────
3) (NGN-Style: Select All That Apply) The nurse is making rounds on a group of
clients when one begins exhibi!ng symptoms of an acute asthma aCack. The
nurse administers a PRN prescrip!on for a short-ac!ng Beta-2 receptor agonist.
Which client responses should the nurse expect? (Select all that apply.)
A. Tachycardia.
B. Increased blood pressure.
C. Rapid resolu!on of wheezing.
D. Improved pulse oximetry values.
E. Reduce fever airway inflamma!on.
Correct Answers: C and D
Expert-Verified Explana/on:
,• Short-ac!ng Beta-2 agonists (e.g., albuterol) quickly dilate the bronchi, reducing
wheezing (C) and improving oxygen satura!on (D).
• Tachycardia (A) may occur, but it is an adverse effect—not the “desired”
improvement.
• Beta-2 agonists do not primarily lower fever or directly treat inflamma!on (E).
────────────────────────────────────────────────────
4) A client prescribed atenolol has a blood pressure of 120/68 mmHg, sinus
bradycardia with a rate of 58 beats/minute, and a PR interval of 0.24. Which
ac!on should the nurse take?
A. Lower the head of the bed and assess the client for orthosta!c changes.
B. Give the medica!on as prescribed and con!nue to monitor the client.
C. Prepare to administer atropine sulfate IV push.
D. Hold the prescribed dose and contact the healthcare provider.
Answer: B. Give the medica!on as prescribed and con!nue to monitor the client.
Expert-Verified Explana/on:
• Atenolol (β1-blocker) o6en causes mild bradycardia and slight PR prolonga!on.
A HR of 58 is not cri!cally low, and the BP is acceptable.
• No clinical signs of instability that would warrant holding or atropine.
────────────────────────────────────────────────────
,5) The nurse is preparing the 0900 dose of losartan (Cozaar), an ARB, for a client
with hypertension and heart failure. The nurse notes the serum potassium is 5.9
mEq/L. Which ac!on should the nurse take first?
A. Withhold the scheduled dose.
B. Check the client’s apical pulse.
C. No!fy the healthcare provider.
D. Repeat the serum potassium level.
Answer: A. Withhold the scheduled dose.
Expert-Verified Explana/on:
• Losartan can worsen hyperkalemia by reducing aldosterone. A potassium of 5.9
is significantly high. Holding the dose prevents further eleva!on.
• Next steps include informing the provider, but the immediate priority is not to
give the drug.
────────────────────────────────────────────────────
6) (NGN-Style, Reordering) A client with acute status asthma!cus is prescribed a
series of medica!ons:
• Salmeterol (Serevent Diskus)
• Albuterol (Proven!l) puffs
• Gentamicin (Garamycin) IM
• Prednisone (Deltasone) orally
,Ques!on: In which order should the nurse administer these medica!ons?
1) Albuterol (Proven!l) puffs
2) Salmeterol (Serevent Diskus)
3) Prednisone (Deltasone) orally
4) Gentamicin (Garamycin) IM
Expert-Verified Explana/on:
• Albuterol (short-ac!ng) first for rapid bronchodila!on.
• Salmeterol (long-ac!ng) next to maintain bronchodila!on.
• Prednisone (steroid) reduces inflamma!on.
• Gentamicin (an!bio!c) last for any suspected infec!on, not cri!cal for
immediate bronchodila!on.
────────────────────────────────────────────────────
7) A client is given a prescrip!on for a scopolamine patch to prevent mo!on
sickness while on a cruise. Which informa!on should the nurse provide?
A. Apply the patch at least 4 hours prior to departure.
B. Change the patch every other day while on the cruise.
C. Place the patch on a hairless area at the base of the skull.
D. Drink no more than 2 alcoholic drinks during the cruise.
Answer: A. Apply the patch at least 4 hours prior to departure.
,Expert-Verified Explana/on:
• Scopolamine patches need about 4 hours for transdermal absorp!on to start
preven!ng mo!on sickness.
• Typically changed every 72 hours, not every other day.
────────────────────────────────────────────────────
8) A client with giardiasis is prescribed metronidazole (Flagyl) 2 grams PO. Which
informa!on should the nurse include?
A. No!fy the clinic of any changes in urine color.
B. Avoid overexposure to the sun.
C. Stop the medica!on a6er the diarrhea resolves.
D. Take the medica!on with food.
Answer: D. Take the medica!on with food.
Expert-Verified Explana/on:
• Metronidazole can upset the GI tract; taking with food minimizes nausea.
• Urine may darken but it’s not typically serious.
• Photosensi!vity is more common with tetracyclines, not metronidazole.
• Complete the full course to eradicate parasites.
────────────────────────────────────────────────────
,9) A female client with rheumatoid arthri!s takes ibuprofen 600 mg PO four !mes
a day. To prevent GI bleeding, misoprostol (Cytotec) 100 mcg PO is prescribed.
Which teaching is most important?
A. Use contracep!on during intercourse.
B. Ensure it is taken on an empty stomach.
C. Promote oral fluids to prevent cons!pa!on.
D. Take Cytotec 30 minutes prior to ibuprofen.
Answer: A. Use contracep!on during intercourse.
Expert-Verified Explana/on:
• Misoprostol is Category X due to its uterotonic effects. Must avoid pregnancy.
────────────────────────────────────────────────────
10) A client with osteoarthri!s gets a new prescrip!on for celecoxib (Celebrex).
The client has a sulfa allergy. Which ac!on is most important before
administering?
A. Review the hemoglobin results.
B. No!fy the healthcare provider.
C. Inquire about the reac!on to sulfa.
D. Take vital signs.
Answer: B. No!fy the healthcare provider.
, Expert-Verified Explana/on:
• Celecoxib is a COX-2 inhibitor with structural similarity to sulfonamides. Must
verify with prescriber in case of cross-allergy.
────────────────────────────────────────────────────
11) A client with new onset SVT is prescribed digoxin. For which lab result should
the nurse contact the HCP immediately?
A. K+ = 3.1 mEq/L
B. Na+ = 132 mEq/L
C. Calcium = 8.6 mg/dL
D. Magnesium = 1.2 mEq/L
Answer: A. K+ = 3.1 mEq/L
Expert-Verified Explana/on:
• Hypokalemia predisposes to digoxin toxicity. A level of 3.1 is dangerously low.
────────────────────────────────────────────────────
12) The nurse is transcribing a new prescrip!on for spironolactone in a client
taking an ACE inhibitor. Which ac!on should the nurse implement?
A. Verify both prescrip!ons with the HCP.
B. Report the medica!on interac!ons to the nurse manager.
V2 EXAM (3 Set Exams)
(NGN style Qs & Case studies)
Actual Qs & Ans to Pass the Exam
This hesi test contains:
passing score Guarantee
Each Exam has 55 Ques and Ans
Format Set of Multiple-choice
questions with incorporating Next Generation
NCLEX (NGN) and Case studies questions
Expert-Verified Explanations & Solutions
,Contents
HESI RN PHARMACOLOGY V2 EXAM ...................... 2
SET 1 ......................................................................... 2
HESI RN PHARMACOLOGY V2 EXAM .................... 37
SET 2 ....................................................................... 37
HESI RN PHARMACOLOGY V2 EXAM .................... 69
SET 3 ....................................................................... 69
HESI RN PHARMACOLOGY V2 EXAM
SET 1
────────────────────────────────────────────────────
1) The nurse is caring for a client who has taken atenolol for 2 years. The
healthcare provider recently changed the medica!on to enalapril to manage the
client’s blood pressure. Which instruc!on should the nurse provide the client
regarding the new medica!on?
A. Take the medica!on at bed!me.
B. Report presence of increased bruising.
, C. Check pulse before taking medica!on.
D. Rise slowly when ge+ng out of bed or chair.
Answer: D. Rise slowly when ge+ng out of bed or chair.
Expert-Verified Explana/on:
• Enalapril (ACE inhibitor) can cause vasodila!on and orthosta!c hypotension.
Teaching the client to stand up slowly helps prevent dizziness or falls.
• “Take at bed!me” (A) is some!mes used for nocturnal BP control, but the
priority is orthosta!c safety.
• “Report bruising” (B) is more relevant to an!coagulants.
• “Check pulse” (C) is more important with beta-blockers.
────────────────────────────────────────────────────
2) A female client calls the clinic and inquires about a possible reac!on a6er
taking amoxicillin for 5 days. She reports having vaginal discomfort, itching, and
white discharge. The nurse should discuss which ac!on with the client?
A. Discon!nue the an!bio!c because original symptoms have subsided.
B. Con!nue taking the medica!on un!l finished un!l the symptoms subside.
C. Consult with a healthcare provider about another treatment for this effect.
D. Use an over-the-counter (OTC) vaginal wash to flush out the secre!ons.
Answer: C. Consult with a healthcare provider about another treatment for this
effect.
,Expert-Verified Explana/on:
• Amoxicillin can disrupt normal flora, some!mes causing a yeast infec!on. The
an!bio!c course must be completed, but an an!fungal may be needed.
• Discon!nuing (A) risks incomplete treatment.
• Merely con!nuing without addressing the infec!on (B) misses the yeast
infec!on concern.
• OTC washes (D) do not fully treat fungal infec!on.
────────────────────────────────────────────────────
3) (NGN-Style: Select All That Apply) The nurse is making rounds on a group of
clients when one begins exhibi!ng symptoms of an acute asthma aCack. The
nurse administers a PRN prescrip!on for a short-ac!ng Beta-2 receptor agonist.
Which client responses should the nurse expect? (Select all that apply.)
A. Tachycardia.
B. Increased blood pressure.
C. Rapid resolu!on of wheezing.
D. Improved pulse oximetry values.
E. Reduce fever airway inflamma!on.
Correct Answers: C and D
Expert-Verified Explana/on:
,• Short-ac!ng Beta-2 agonists (e.g., albuterol) quickly dilate the bronchi, reducing
wheezing (C) and improving oxygen satura!on (D).
• Tachycardia (A) may occur, but it is an adverse effect—not the “desired”
improvement.
• Beta-2 agonists do not primarily lower fever or directly treat inflamma!on (E).
────────────────────────────────────────────────────
4) A client prescribed atenolol has a blood pressure of 120/68 mmHg, sinus
bradycardia with a rate of 58 beats/minute, and a PR interval of 0.24. Which
ac!on should the nurse take?
A. Lower the head of the bed and assess the client for orthosta!c changes.
B. Give the medica!on as prescribed and con!nue to monitor the client.
C. Prepare to administer atropine sulfate IV push.
D. Hold the prescribed dose and contact the healthcare provider.
Answer: B. Give the medica!on as prescribed and con!nue to monitor the client.
Expert-Verified Explana/on:
• Atenolol (β1-blocker) o6en causes mild bradycardia and slight PR prolonga!on.
A HR of 58 is not cri!cally low, and the BP is acceptable.
• No clinical signs of instability that would warrant holding or atropine.
────────────────────────────────────────────────────
,5) The nurse is preparing the 0900 dose of losartan (Cozaar), an ARB, for a client
with hypertension and heart failure. The nurse notes the serum potassium is 5.9
mEq/L. Which ac!on should the nurse take first?
A. Withhold the scheduled dose.
B. Check the client’s apical pulse.
C. No!fy the healthcare provider.
D. Repeat the serum potassium level.
Answer: A. Withhold the scheduled dose.
Expert-Verified Explana/on:
• Losartan can worsen hyperkalemia by reducing aldosterone. A potassium of 5.9
is significantly high. Holding the dose prevents further eleva!on.
• Next steps include informing the provider, but the immediate priority is not to
give the drug.
────────────────────────────────────────────────────
6) (NGN-Style, Reordering) A client with acute status asthma!cus is prescribed a
series of medica!ons:
• Salmeterol (Serevent Diskus)
• Albuterol (Proven!l) puffs
• Gentamicin (Garamycin) IM
• Prednisone (Deltasone) orally
,Ques!on: In which order should the nurse administer these medica!ons?
1) Albuterol (Proven!l) puffs
2) Salmeterol (Serevent Diskus)
3) Prednisone (Deltasone) orally
4) Gentamicin (Garamycin) IM
Expert-Verified Explana/on:
• Albuterol (short-ac!ng) first for rapid bronchodila!on.
• Salmeterol (long-ac!ng) next to maintain bronchodila!on.
• Prednisone (steroid) reduces inflamma!on.
• Gentamicin (an!bio!c) last for any suspected infec!on, not cri!cal for
immediate bronchodila!on.
────────────────────────────────────────────────────
7) A client is given a prescrip!on for a scopolamine patch to prevent mo!on
sickness while on a cruise. Which informa!on should the nurse provide?
A. Apply the patch at least 4 hours prior to departure.
B. Change the patch every other day while on the cruise.
C. Place the patch on a hairless area at the base of the skull.
D. Drink no more than 2 alcoholic drinks during the cruise.
Answer: A. Apply the patch at least 4 hours prior to departure.
,Expert-Verified Explana/on:
• Scopolamine patches need about 4 hours for transdermal absorp!on to start
preven!ng mo!on sickness.
• Typically changed every 72 hours, not every other day.
────────────────────────────────────────────────────
8) A client with giardiasis is prescribed metronidazole (Flagyl) 2 grams PO. Which
informa!on should the nurse include?
A. No!fy the clinic of any changes in urine color.
B. Avoid overexposure to the sun.
C. Stop the medica!on a6er the diarrhea resolves.
D. Take the medica!on with food.
Answer: D. Take the medica!on with food.
Expert-Verified Explana/on:
• Metronidazole can upset the GI tract; taking with food minimizes nausea.
• Urine may darken but it’s not typically serious.
• Photosensi!vity is more common with tetracyclines, not metronidazole.
• Complete the full course to eradicate parasites.
────────────────────────────────────────────────────
,9) A female client with rheumatoid arthri!s takes ibuprofen 600 mg PO four !mes
a day. To prevent GI bleeding, misoprostol (Cytotec) 100 mcg PO is prescribed.
Which teaching is most important?
A. Use contracep!on during intercourse.
B. Ensure it is taken on an empty stomach.
C. Promote oral fluids to prevent cons!pa!on.
D. Take Cytotec 30 minutes prior to ibuprofen.
Answer: A. Use contracep!on during intercourse.
Expert-Verified Explana/on:
• Misoprostol is Category X due to its uterotonic effects. Must avoid pregnancy.
────────────────────────────────────────────────────
10) A client with osteoarthri!s gets a new prescrip!on for celecoxib (Celebrex).
The client has a sulfa allergy. Which ac!on is most important before
administering?
A. Review the hemoglobin results.
B. No!fy the healthcare provider.
C. Inquire about the reac!on to sulfa.
D. Take vital signs.
Answer: B. No!fy the healthcare provider.
, Expert-Verified Explana/on:
• Celecoxib is a COX-2 inhibitor with structural similarity to sulfonamides. Must
verify with prescriber in case of cross-allergy.
────────────────────────────────────────────────────
11) A client with new onset SVT is prescribed digoxin. For which lab result should
the nurse contact the HCP immediately?
A. K+ = 3.1 mEq/L
B. Na+ = 132 mEq/L
C. Calcium = 8.6 mg/dL
D. Magnesium = 1.2 mEq/L
Answer: A. K+ = 3.1 mEq/L
Expert-Verified Explana/on:
• Hypokalemia predisposes to digoxin toxicity. A level of 3.1 is dangerously low.
────────────────────────────────────────────────────
12) The nurse is transcribing a new prescrip!on for spironolactone in a client
taking an ACE inhibitor. Which ac!on should the nurse implement?
A. Verify both prescrip!ons with the HCP.
B. Report the medica!on interac!ons to the nurse manager.
