Chapter 01:Cellular Biology ................................................................................................................................4
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Chapter 02:Genes and Genetic Diseases ............................................................................................................. 13
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Chapter 03:Epigenetics and Disease .................................................................................................................. 23
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Chapter 04:Altered Cellular and Tissue Biology ................................................................................................... 27
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Huether & McCance:Understanding Pathophysiology,6th Edition ......................................................................... 39
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Chapter 06:Innate Immunity:Inflammation and Wound Healing Huether & McCance:Understanding Pathophysiology,
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6th Edition ...................................................................................................................................................... 48
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Chapter 07:Adaptive Immunity ......................................................................................................................... 60
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Chapter 08:Infection and Defects in Mechanisms of Defense Huether & McCance:Understanding Pathophysiology,6th
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Edition ........................................................................................................................................................... 66
SINGTB.COM .................................................................................................................................................. 74
Chapter 09:Stress and Disease .......................................................................................................................... 76
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Chapter 10:Biology,ClinicalManifestations,and Treatment of Cancer Huether & McCance:Understanding Pathophysi
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ology,6th Edition ............................................................................................................................................. 81
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Chapter 11:Cancer Epidemiology ...................................................................................................................... 87
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Chapter 12:Cancer in Children........................................................................................................................... 91
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Chapter 13:Structure and Function of theNeurologic SystemHuether & McCance:Understanding Pathophysiology,6th
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Edition ........................................................................................................................................................... 94
Chapter 14:Pain,Temperature,Sleep,and Sensory Function Huether & McCance:Understanding Pathophysiology,6th
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Edition ......................................................................................................................................................... 105
Chapter 15:Alterations in Cognitive Systems,CerebralHemodynamics,and Motor Function.................................... 116
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Chapter 16:Disorders of theCentraland PeripheralNervous Systems and theNeuromuscular Junction....................... 126
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Chapter 17:Alterations of Neurologic Function in Children Huether & McCance:Understanding Pathophysiology, 6th E
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dition ........................................................................................................................................................... 138
Chapter 18:Mechanisms of HormonalRegulation .............................................................................................. 147
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Chapter 19:Alterations of HormonalRegulation ................................................................................................. 156
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Chapter 20:Structure and Function of the Hematologic SystemHuether & McCance:Understanding Pathophysiology,6t
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h Edition ....................................................................................................................................................... 169
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Chapter 21:Alterations of Hematologic Function ................................................................................................ 176
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INGTB.COM .................................................................................................................................................. 177
Chapter 22:Alterations of Hematologic Function in Children Huether & McCance:Understanding Pathophysiology, 6th
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Edition ......................................................................................................................................................... 192
Chapter 23:Structure and Function of the Cardiovascular and Lymphatic Systems Huether & McCance:UnderstandingP
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athophysiology,6th Edition ............................................................................................................................. 200
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Chapter 24:Alterations of Cardiovascular Function ............................................................................................ 210
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U SNTl l O...................................................................................................................................................... 210
SINGTB.COM ................................................................................................................................................ 223
U SNTl l O...................................................................................................................................................... 226
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Chapter 25:Alterations of Cardiovascular Function in Children Huether & McCance:Understanding Pathophysiology,6
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th Edition ...................................................................................................................................................... 229
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Chapter 26:Structure and Function of the Pulmonary SystemHuether & McCance:Understanding Pathophysiology,6th
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Edition ......................................................................................................................................................... 236
Chapter 27:Alterations of Pulmonary Function................................................................................................... 245
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, Chapter 28:Alterations of Pulmonary Function in Children Huether & McCance:Understanding Pathophysiology,6th E
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dition ........................................................................................................................................................... 257
Chapter 29:Structure and Function of the Renaland Urologic Systems Huether & McCance:Understanding Pathophysiol
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ogy,6th Edition .............................................................................................................................................. 265
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Chapter 30:Alterations of Renaland Urinary Tract Function Huether & McCance:Understanding Pathophysiology,6th
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Edition ......................................................................................................................................................... 273
Chapter 31:Alterations of Renaland Urinary Tract Function in Children Huether & McCance:Understanding Pathophysi
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ology,6th Edition ........................................................................................................................................... 280
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Chapter 32:Structure and Function of the Reproductive Systems Huether & McCance:Understanding Pathophysiology,
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6th Edition .................................................................................................................................................... 286
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Chapter 33:Alterations of the Female Reproductive SystemHuether & McCance:Understanding Pathophysiology, 6th E
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dition ........................................................................................................................................................... 295
Chapter 34:Alterations of the Male Reproductive System .................................................................................... 300
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Chapter 35:Structure and Function of the Digestive SystemHuether & McCance:Understanding Pathophysiology,6th E
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dition ........................................................................................................................................................... 305
Chapter 36:Alterations of Digestive Function..................................................................................................... 312
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Chapter 37:Alterations of Digestive Function in Children..................................................................................... 325
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Chapter 38:Structure and Function of the Musculoskeletal SystemHuether & McCance:Understanding Pathophysiolog
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y,6th Edition.................................................................................................................................................. 334
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Chapter 39:Alterations of MusculoskeletalFunction ........................................................................................... 342
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Chapter 40:Alterations of Musculoskeletal Function in Children Huether & McCance:Understanding Pathophysiology,
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6th Edition .................................................................................................................................................... 352
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Chapter 41:Structure,Function,and Disorders of the Integument Huether & McCance:Understanding Pathophysiology,
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6th Edition .................................................................................................................................................... 357
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Chapter 42:Alterations of the Integument in Children .......................................................................................... 366
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, Chapter 01:Cellular Biology
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Huether &McCance:Understanding P athophysiology,6thEdition
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MULTIPLE CHOICE l
1. A student is observinga cell under the microscope. It is observed to have supercoiledDNA with hi
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stones. Whichof the following would also be observed bythe student?
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a. A single circular chromosome l l l
b. A nucleus l
c. Free-floatingnuclear material l l
d. No organelles l
ANS: B l
The celldescribed is a eukaryotic cell, so it has histones and a supercoiled DNA within its nucleus; th
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us, the nucleus should be observed. Asingle circular chromosome called a prokaryote contains free
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-floating nuclear material but has no organelles. l l l l l l
REF:p. 2 l l
2. A nurse is instructingthe staffabout cellular functions. Whichcellular function is the nurse describ
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ingwhenan isolated cell absorbs oxygenand uses it to transform nutrients toe nergy?
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a. Metabolic absorption l
b. Communication
c. Secretion
d. Respiration
ANS:D l
The cell’s abilityto absorb oxygen is referred to as respirationwhile its communicationability involves ma
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intenance of a steadydynamic state, metabolic absorptionprovides nutrition, and secretionallows for the s
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ynthesizingof new substances. l l l
REF:p. 2 l l
3. A eukaryotic cell is undergoingDNA replication. In whichregionof the cell would most of the gen
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etic informationbe contained?
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a. Mitochondria
b. Ribosome
c. Nucleolus
d. Nucleus Cytoplasm l
ANS:C l
The regionofthe cell that contains genetic material, includinga large amount of ribonucleic acid, mo
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st ofthe DNA, and DNA-
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bindingproteins, is the nucleolus, which is located withinthe cell’s nucleus. Mitochondria is associ
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ated withcellular respiration, while ribosomes are involved withprotein manufacturing. Cytoplas
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mis a fluid filling that is a component ofthe cell.
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REF:p. 2 l l