m m m m m m
nk.
,Chapter m01:mIntroductionmto mPathophysiology mBan
asik:mPathophysiology,m7thmEdition
MULTIPLEmCHOICE
1. C.Q.mwasmrecentlymexposed mtomgroupmA mhemolyticmStreptococcusmand msubsequentlymdeveloped
a pharyngealminfection.mHismclinicmexaminationmrevealsmanmoralmtemperaturemof m102.3°F,mskinm
m m
rash,mdysphagia,mand mreddened mthroat mmucosamwithmmultiplempustules.mHemcomplainsmof msoremt
hroat,mmalaise,mand mjoint mstiffness.mAmthroat mculturemismpositivemformStreptococcus,mand mantibio
ticsmhavembeenmprescribed.mThemetiologymof mC.Q.’smdiseasemis
a. amsoremthroat.
b. streptococcalminfection.
c. geneticmsusceptibility.
d. pharyngitis.
ANS:mB
Etiologymrefersmtomthemproposed mcausemormcausesmof mamparticularmdiseasemprocess.mAmsoremthroat m
ismthemmanifestationmof mthemdiseasemprocess.mGeneticmsusceptibilitymrefersmtominherited mtendency
mtomdevelopmamdisease.mPharyngitismrefersmtominflammationmof mthemthroat mand mismalsomamclinicalm
manifestationmof mthemdiseasemprocess.
2. A m17-year-old mcollege-
bound mstudent mreceivesmamvaccinemagainst manmorganismmthat mcausesmmeningitis.mThismism
anmexamplemof
a. primarymprevention.
b. secondarymprevention.
c. tertiarymprevention.
d. diseasemtreatment.
ANS:mA
Primarympreventionmismpreventionmof mdiseasembymalteringmsusceptibilitymormreducingmexposuremf
ormsusceptiblemindividuals,minmthismcasembymprovidingmvaccination.mSecondarympreventionmismth
emearlymdetection,mscreening,mand mmanagement mof mthemdisease.mTertiarympreventionmincludesmr
ehabilitativemand msupportivemcaremand mattemptsmtomalleviatemdisabilitymand mrestoremeffectivemfu
nctioning.mDiseasemtreatment minvolvesmmanagement mof mthemdiseasemoncemit mhasmdeveloped.
3. Anmobesembut motherwisemhealthymteenmismgivenmamprescriptionmformamlow-
caloriemdiet mand mexercisemprogram.mThismismanmexamplemof
a. primarymprevention.
b. secondarymprevention.
c. tertiarymprevention.
d. diseasemtreatment.
ANS:mB
Secondarympreventionmismthemearlymdetection,mscreening,mand mmanagement mof mthemdiseasemsuchm
asmprescribingmdiet mand mexercisemformanmindividualmwhomhasmalreadymdeveloped mobesity.mPrimar
ympreventionmismpreventionmof mdiseasembymalteringmsusceptibilitymor mreducingmexposuremformsusc
eptiblemindividuals.mTertiarympreventionmincludesmrehabilitativemand msupportivemcare mand mattem
ptsmtomalleviatemdisabilitymand mrestoremeffectivemfunctioning.mDiseasemtreatment minvolvesmmanag
ement mof mthemdiseasemoncemit mhasmdeveloped.
,4. A mpatient mwithmhighmblood mpressuremwhomismotherwisemhealthymismcounseled mtomrestrict msodi
ummintake.mThismismanmexamplemof
a. primarymprevention.
b. secondarymprevention.
c. tertiarymprevention.
d. diseasemtreatment.
ANS:mB
Secondarympreventionmismthemearlymdetection,mscreening,mand mmanagement mof mthemdisease,msuc
hmasmbymprescribingmsodiummrestrictionmformhighmblood mpressure.mPrimarympreventionmismpreven
tionmof mdiseasembymalteringmsusceptibilitymormreducingmexposuremformsusceptiblemindividuals.m T
ertiarympreventionmincludesmrehabilitativemand msupportivemcaremand mattemptsmtomalleviatemdisab
ilitymand mrestoremeffectivemfunctioning.mDiseasemtreatment minvolvesmmanagement mof mthemdiseas
emoncemit mhasmdeveloped.
5. Aftermsufferingmamheart mattack,mammiddle-aged mmanmismcounseled mtomtakemamcholesterol-
loweringmmedication.mThismismanmexample mof
a. primarymprevention.
b. secondarymprevention.
c. tertiarymprevention.
d. diseasemtreatment.
ANS:mC
Tertiarympreventionmincludesmrehabilitativemand msupportivemcarem and mattemptsmtomalleviatemdisa
bilitymand mrestoremeffectivemfunctioningmsuchmasmprescribingmamcholesterol-
loweringmmedicationmfollowingmamheart mattack.mPrimarympreventionmismpreventionmof mdiseasembym
alteringmsusceptibilitymormreducingmexposuremformsusceptiblemindividuals.mSecondarymprevention
mismthemearlymdetection,mscreening,mand mmanagement mof mthemdisease.mDiseasemtreatment minvolve
smmanagement mof mthemdiseasemoncemit mhasmdeveloped.
6. A mpatient mhasmbeenmexposed mtommeningococcalmmeningitis,mbut mismnot myet mdemonstratingmsigns
mof mthismdisease.mThismstagemof millnessmismcalled mthe stage.
a. prodromal
b. latent
c. sequela
d. convalescence
ANS:mB
Incubationmrefersmtomthemintervalmbetweenmexposuremof mamtissuemtomanminjuriousmagent mand mthemfir
st mappearancemof msignsmand msymptoms.mInminfectiousmdiseases,mthismperiod mismoftenmcalled mthemi
ncubationm(latent)mperiod.mProdromalmrefersmtomthemappearancemof mthemfirst msignsmand msymptom
smindicatingmthemonset mof mamdisease.mThesemaremoftenmnonspecific,msuchmasmheadache,mmalaise, ma
norexia,mand mnausea,mwhichmaremassociated mwithmamnumbermof mdifferent mdiseases.mSequelamrefer
smtomsubsequent mpathologicmconditionmresultingmfrommamdisease.mConvalescencemismthemstagemof m
recoverymaftermamdisease,minjury,mormsurgicalmoperation.
7. A mdiseasemthat mismnativemtomamparticularmregionmismcalled
a. epidemic.
b. endemic.
c. pandemic.
d. ethnographic.
, ANS:mB
A mdiseasemthat mismnativemtomamparticularmregionmismcalled mendemic.mAnmepidemicmismamdiseasemtha
t mspreadsmtommanymindividualsmat mthemsamemtime.mPandemicsmaremepidemicsmthat maffect mlargemge
ographicmregions,mperhapsmspreadingmworldwide.mEthnographicmdoesmnot mdescribemamdiseasemdi
stributionmpattern.
8. Inmgeneral,mwithmaging,morganmsizemand mfunction
a. increase.
b. decrease.
c. remainmthemsame.
d. aremunknown.
ANS:mB
Inmgeneral,mwithmaging,morganmsizemand mfunctionmdecrease.
9. Themstagemduringmwhichmthempatient mfunctionsmnormally,malthoughmthemdiseasemprocessesmaremw
ellmestablished,mismreferred mtomas
a. latent.
b. subclinical.
c. prodromal.
d. convalescence.
ANS:mB
Themstagemduringmwhichmthempatient mfunctionsmnormally,malthoughmthemdiseasemprocessesmaremw
ellmestablished,mismcalled mthemsubclinicalmstage.m Them intervalmbetweenmexposuremof mamtissuemtom
anminjuriousmagent mand mthemfirst mappearancemof msignsmand msymptomsmmaymbemcalled mamlatent mpe
riod mor,minmthemcasemof minfectiousmdiseases,manmincubationmperiod.mThemprodromalmperiod,mormpr
odrome,mrefersmtomthemappearancemof mthemfirst msignsmand msymptomsmindicatingmthemonset mof mamd
isease.mConvalescencemismthemstagemof mrecoverymaftermamdisease,minjury, mormsurgicalmoperation.
MULTIPLEmRESPONSE
1. Yourmpatient’smred mblood mcellmcount mismslightlymelevated mtoday.mThismmight mbemexplained m
bym(Selectmallmthatmapply.)
a. gendermdifference.
b. situationalmfactors.
c. normalmvariation.
d. culturalmvariation.
e. illness.
ANS:mA,mB,mC,mE
Gender,msituationsm(e.g.,maltitude),mnormalmvariations,mand millnessmmaymallmdeterminemred mblood
mcellmcount.mCulturemaffectsmhow mmanifestationsmaremperceivedm(normalmversusmabnormal).
2. Socioeconomicmfactorsminfluencemdiseasemdevelopment mbecausemof m(Selectmallmthatmapply.)
a. genetics.
b. environmentalmtoxins.
c. overcrowding.
d. nutrition.
e. hygiene.