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Screening for children who meet the following criteria should begin at
age 10 and occur every 3 years thereafter:
1. BMI above the 85th percentile for age and sex
2. Family history of diabetes in first- or second-degree relative
3. Hypertension based on criteria for children
4. Any of the above - Correct Answer - 4. Any of the above
Insulin is used to treat both types of diabetes. It acts by:
1. Increasing beta cell response to low blood-glucose levels
2. Stimulating hepatic glucose production
3. Increasing peripheral glucose uptake by skeletal muscle and fat
4. Improving the circulation of free fatty acids - Correct Answer - 3.
Increasing peripheral glucose uptake by skeletal muscle and fat
Adam has type 1 diabetes and plays tennis for his university. He exhibits
a knowledge deficit about his insulin and his diagnosis. He should be
taught that:
1. He should increase his carbohydrate intake during times of exercise.
,2. Each brand of insulin is equal in bioavailability, so buy the least
expensive.
3. Alcohol produces hypoglycemia and can help control his diabetes
when taken in small amounts.
4. If he does not want to learn to give himself injections, he may
substitute an oral hypoglycemic to control his diabetes. - Correct Answer
- 1. He should increase his carbohydrate intake during times of exercise.
Insulin preparations are divided into categories based on onset, duration,
and intensity of action following subcutaneous injection. Which of the
following insulin preparations has the shortest onset and duration of
action?
1. Lispro
2. Glulisine
3. Glargine
4. Detemir - Correct Answer - 2. Glulisine
The drug of choice for type 2 diabetics is metformin. Metformin:
1. Decreases glycogenolysis by the liver
2. Increases the release of insulin from beta cells
3. Increases intestinal uptake of glucose
4. Prevents weight gain associated with hyperglycemia - Correct Answer
- 1. Decreases glycogenolysis by the liver
, Before prescribing metformin, the provider should:
1. Draw a serum creatinine level to assess renal function.
2. Try the patient on insulin.
3. Prescribe a thyroid preparation if the patient needs to lose weight.
4. All of the above - Correct Answer - 1. Draw a serum creatinine level to
assess renal function.
Sulfonylureas may be added to a treatment regimen for type 2 diabetics
when lifestyle modifications and metformin are insufficient to achieve
target glucose levels. Sulfonylureas have been moved to Step 2 therapy
because they:
1. Increase endogenous insulin secretion
2. Have a significant risk for hypoglycemia
3. Address the insulin resistance found in type 2 diabetics
4. Improve insulin binding to receptors - Correct Answer - 2. Have a
significant risk for hypoglycemia
Dipeptidyl peptidase-4 inhibitors (gliptins) act on the incretin system to
improve glycemic control. Advantages of these drugs include:
1. Better reduction in glucose levels than other classes
2. Less weight gain than sulfonylureas
3. Low risk for hypoglycemia