1960s Correct Answers "speed scene"
speedball = amphetamines + heroine
amphetamines became more tightly controlled
- inc. cocaine used, inc. meth use
**IN 1950s/60s MOST AMPHETAMINES COME FROM
PRESCRIPTIONS**
1985 cocaine Correct Answers most common form = cocaine
HCl
Acute Toxicity (amphetamines) Correct Answers inc feelings
of power, suspicion, and paranoia
in animals, high doses may destroy catecholamine neurons
- amount actually used by humans isn't this high
Acute Toxicity (Cocaine) Correct Answers no evidence that
small amounts are bad for health (but it might burn out
receptors)
illicit coke = adulterated (not pure, cute with poisons)
respiratory or cardiac arrest
ADHD and amphetamines Correct Answers can reverse
catecholamine-associated deficits that cause ADHD
Amotivational Syndrome Correct Answers lab data shows that
inc. marijuana smoking does NOT correlate to lower motivation
Amphetamine Pharmacology Correct Answers stimulates
release of dop, ser, and nore
, structure easily allowed to cross blood-brain barrier (BBB)
structure similar to catecholamine
ephedrine less able to cross BBB (more peripheral)
Amphetamines Correct Answers synthesized chemical similar
to ephedrine
patented in 1932
Anti-Drug Abuse Act of 1986 Correct Answers penalties for
sale of crack higher than Cocaine HCl
Anxiety Correct Answers fear of loss of control
- "talk down" is helpful
frontal lobe affected by smoking weed
- as a result, "talking down" is harder to do
Beneficial Uses of Amphetamines Correct Answers depression
treatment
- 1950s-60s
- now used as adjunctive therapy
- major advantage: antidepressant effect onset quickly
weight control
- 1960s
- dec. food intake & dec. weight for SHORT periods of time
-methamphetamine = FDA approved (long-term effects unclear)
narcolepsy
- activate sympathetic NS
"smart pills"
- low levels = may cause slight inc. in performence
- high levels = may cause slight dec. in performance
athletics