C HAPTER 27: A NTILIPEMIC D RUGS
Lilley: Pharmacology and the Nursing Process, 10th Edition
MULTIPLE CHOICE
1. A patient with coronary artery disease asks the nurse about the “good
cholesterol ” laboratory values. The nurse knows that “good cholesterol ”
refers to which lipids?
a. Trigl ycerides
b. Low-densit y lipoproteins (LDLs)
c. Very–low-densit y lipoproteins (VLDLs)
d. High-densit y lipoproteins (HDLs)
ANS: D
HDLs are responsible for the “recycling” of cholesterol. HDLs are
sometimes referred to as the “good” lipid (or good cholesterol) because
they are believed to be cardioprotective. LDLs are known as the “bad”
cholesterol.
DIF: Cognitive Level: Understanding (Comprehension)
TOP: Nursing Process: Implementation
MSC: NC LEX: Physiological Integrit y: Physiological Adaptation
2. A patient who has recentl y started therapy on a statin drug ask s the nurse
how long it will take until he sees an effect on his serum cholesterol.
Which statement would be the nurse ’s best response?
a. “Blood levels return to normal within a week of beginning therapy. ”
b. “It takes 6 to 8 weeks to see a change in cholestero l levels. ”
c. “It takes at least 6 months to see a change in cholesterol levels. ”
, d. “You will need to take this medication for almost a year to see
significant results. ”
ANS: B
The maximum extent to which lipid levels are lowered may not occur
until 6 to 8 weeks after the start of therapy. The other responses are
incorrect.
DIF: Cognitive Level: Appl ying (Application)
TOP: Nursing Process: Implementation
MSC: NC LEX: Physiological Integrit y: Physiological Adaptation
3. The nurse will monitor for m yopathy (muscle p ain) when a patient is
taking which class of antilipemic drugs?
a. Niacin
b. HMG–CoA reductase inhibitors
c. Fibric acid derivatives
d. Bile acid sequestrants
ANS: B
M yopathy (muscle pain) is a clinicall y important adverse effect that
may occur with HMG–CoA reductase inhibitors. It may progress to a
serious condition known as rhabdom yol ysis. Patients receiving statin
therapy need to be advised to report any unexplained muscular pain or
discomfort to their health care providers immediatel y. The other drugs
and drug classes do not cause muscle pain or m yopathy.
DIF: Cognitive Level: Appl ying (Application)
TOP: Nursing Process: Assessment
MSC: NC LEX: Physiological Integrit y: Physiological Adaptation
Lilley: Pharmacology and the Nursing Process, 10th Edition
MULTIPLE CHOICE
1. A patient with coronary artery disease asks the nurse about the “good
cholesterol ” laboratory values. The nurse knows that “good cholesterol ”
refers to which lipids?
a. Trigl ycerides
b. Low-densit y lipoproteins (LDLs)
c. Very–low-densit y lipoproteins (VLDLs)
d. High-densit y lipoproteins (HDLs)
ANS: D
HDLs are responsible for the “recycling” of cholesterol. HDLs are
sometimes referred to as the “good” lipid (or good cholesterol) because
they are believed to be cardioprotective. LDLs are known as the “bad”
cholesterol.
DIF: Cognitive Level: Understanding (Comprehension)
TOP: Nursing Process: Implementation
MSC: NC LEX: Physiological Integrit y: Physiological Adaptation
2. A patient who has recentl y started therapy on a statin drug ask s the nurse
how long it will take until he sees an effect on his serum cholesterol.
Which statement would be the nurse ’s best response?
a. “Blood levels return to normal within a week of beginning therapy. ”
b. “It takes 6 to 8 weeks to see a change in cholestero l levels. ”
c. “It takes at least 6 months to see a change in cholesterol levels. ”
, d. “You will need to take this medication for almost a year to see
significant results. ”
ANS: B
The maximum extent to which lipid levels are lowered may not occur
until 6 to 8 weeks after the start of therapy. The other responses are
incorrect.
DIF: Cognitive Level: Appl ying (Application)
TOP: Nursing Process: Implementation
MSC: NC LEX: Physiological Integrit y: Physiological Adaptation
3. The nurse will monitor for m yopathy (muscle p ain) when a patient is
taking which class of antilipemic drugs?
a. Niacin
b. HMG–CoA reductase inhibitors
c. Fibric acid derivatives
d. Bile acid sequestrants
ANS: B
M yopathy (muscle pain) is a clinicall y important adverse effect that
may occur with HMG–CoA reductase inhibitors. It may progress to a
serious condition known as rhabdom yol ysis. Patients receiving statin
therapy need to be advised to report any unexplained muscular pain or
discomfort to their health care providers immediatel y. The other drugs
and drug classes do not cause muscle pain or m yopathy.
DIF: Cognitive Level: Appl ying (Application)
TOP: Nursing Process: Assessment
MSC: NC LEX: Physiological Integrit y: Physiological Adaptation
