Canadian Health Care Practice Chapter 1,
2,19-22 Latest Update by Kara Sealock,
Cydnee Seneviratne Verified Key Download
Absorption - Correct Answers--Bioavailability
-First pass effect
-Routes: enteral, sublingual, buccal, topical, transdermal, inhalation route, and parenteral.
Acute therapy - Correct Answers-Intensive drug therapy, critically ill, emergency
additive effect - Correct Answers-1+1=2
when two drugs with similar actions are given together
Adverse drug event - Correct Answers-broad term for any undesirable occurrence involving
medications
-medication error
-adverse drug withdrawal event
-adverse drug interaction
-allergic reaction
-idiosyncratic reaction
-other drug events
adverse drug interaction - Correct Answers-results when two drugs interact and produce an unwanted
effect
Adverse drug withdrawal event - Correct Answers-adverse outcome associated with discontinuation of
drug therapy
Albumin - Correct Answers-most important protein in blood and carries the majority of protein-bound
drug molecules
allergic reaction - Correct Answers-An immunologic hypersensitivity reaction resulting from the
unusual sensitivity of a patient to a particular medication
antagonist effect - Correct Answers-1+1= less than 2
combined effect of two or more drugs that produces less than the effect of each drug alone
, Bioavailability - Correct Answers-A measure of the extent of drug absorption for a given drug and
route (from 0% to 100%).
Bioequivalent - Correct Answers-two drugs absorbed at the same time, similar action and metabolism
Biotransformation (metabolism) - Correct Answers-one or more biochemical reactions involving a
parent drug; occurs mainly in the liver and produces a metabolite that is either inactive or active, more
soluble or potent (inactive to active)
Consider a medication that has a half-life of 2.5 hours. at 0800 hours, the nurse measures the medication
as 100 mg/L. What will the medication level be at 1300 hours - Correct Answers-0 2.5 5
100 50 25
0800 1030 1300
25mg/L at 1300 hours
Cytochrome P450 - Correct Answers-enzyme in the liver that breaks down drugs.
dependence - Correct Answers-physiologic or psychological need for a drug
Distribution - Correct Answers-transport of a drug by the bloodstream to its site of action
Drug classification - Correct Answers-Categorization based on various characteristics, including the
chemical structure of a drug, the action of a drug, and/or the therapeutic or anatomical use of a drug
Drug interactions - Correct Answers-alteration of the action of one drug by another
Drug Names - Correct Answers-chemical, generic, trade
Drug Names: Chemical - Correct Answers-provides the exact description of medication's composition
Drug Names: Generic - Correct Answers-official or non-proprietary name, often derived from
chemical name
Drug Names: Trade - Correct Answers-also known as brand or proprietary name. This is the name
under which a manufacturer markets the medication.
duration of action - Correct Answers-The length of time the concentration of a drug in the blood or
tissues is sufficient to elicit a response.
empirical therapy - Correct Answers-The administration of antibiotics according to a patient's
symptoms and one's understanding of infectious disease before the pathogen has been identified; used in
life-threatening situations, such as meningitis.
enteral route - Correct Answers--Absorbed into the systemic circulation through the oral or gastric
mucosa or the small intestine.
-Oral, Sublingual, Buccal, Rectal