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,ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
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,ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
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, ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
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Chapter 1, The Foundation of Pharmacology: Quality and Safety
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1. A woman diagnosed with obsessive–
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compulsive disorder has been prescribed oralparoxetine hydrochloride. What is the e ki ki ki ki ki ki ki ki ki ki ki
xpected effect for this prescription? ki ki ki ki
A. Curative effect on symptoms ki ki ki
B. Systemic effect on symptoms ki ki ki
C. Local effect on symptoms ki ki ki
D. Parenteral effect on symptoms ki ki ki
ANS: B k i
Rationale: Drugs that produce systemic effects are taken into the body, circulated through the b
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loodstream to their sites of action in various body tissues, and eventually eliminated from the b
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ody. Curative agents are given to cure a disease process. In this case, paroxetine hydrochloride
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will control the symptoms but not cure the disorder. Drugs with local effects,such as sunscreen a
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nd local anesthetics, act mainly at the site of application. Paroxetine hydrochloride is not admin
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istered parenterally. Parenteral agents are administered subcutaneously, intramuscularly, or in
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travenously.
PTS: 1 REF: p. 3, Introduction OBJ: 1 ki ki
NAT: k i Client Needs: Physiological Integrity: Pharmacological and Parenteral TherapiesT
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k
OP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety ki ki ki ki ki ki ki ki
KEY: k i Integrated Process: Nursing Process ki ki ki
BLM: k Cognitive Level: Understand
i NOT: Multiple Choice ki ki k i ki
2. A client has been prescribed an antibiotic. This medication is a naturally occurring
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substance that has been cheG
mRicAalDlyEm
SoBdOifOieSd.TWhaOtM
.C is another name for this type of medicat
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ion?
A. Synthetic drug ki
B. Semisynthetic drug ki
C. Biotechnology drug ki
D. Prototype drug ki
ANS: B k i
Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances that
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have been chemically modified. Synthetic drugs are more standardized in their chemicalcharact
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k
eristics, more consistent in their effects, and less likely to produce allergic reactions. Biotechnol
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ogy drugs involve manipulating DNA and RNA and recombining genes into hybrid molecules t
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hat can be inserted into living organisms. Prototype drugs are the first drug of a particular group t
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o be developed.
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PTS: 1 REF: p. 3, Drug Sources OBJ: 1 ki ki ki
NAT: k i Client Needs: Physiological Integrity: Pharmacological and Parenteral TherapiesT
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k
OP: Chapter: 1: The Foundation of Pharmacology: Quality and Safety ki ki ki ki ki ki ki ki
KEY: k i Integrated Process: Nursing Process ki ki ki
BLM: k Cognitive Level: Understand
i NOT: Multiple Choice ki ki k i ki
3. Which classification applies to morphine? ki ki ki ki
A. Central nervous system depressant ki ki ki
B. Central nervous system stimulant ki ki ki
ABRAMS' CLINICAL DRUG THERAPY: RATIONALES FOR NURSING PRACTICE
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