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MCB5252 Exam#2 Practice Questions And
Answers.
Which of the following is not true?
A) Both Cytotoxic T cells and NK cells can kill cancer cells
B) Acquired (Secondary) immune deficiency is the result of genetic or developmental defects
C) Adaptive, acquired, and specific immunity all refer to the same thing
D) Antibodies can bind to the surface of bacteria, but they cannot directly lyse them -
Answers✔B) Acquired (Secondary) immune deficiency is the result of genetic or developmental
defects
Which of the following is NOT TRUE of antigens?
A) Haptens become antigenic if they bind to larger carrier molecules
B) Antigens have size restriction and should be large enough for the immune system to detect
them
C) Polysaccharides are the most antigenic of all polymers
D) Antigens could be found on the surface of bacteria - Answers✔C) Polysaccharides are the
most antigenic of all polymers
Antigens presenting cells (APC's) process by__cells, and present antigens to__cells.
A) Macrophage/Neutrophilis
B) B cells/ Helper T Cell
C) Helper T cells/ plasma cell
D) Cytotoxic T Cells/ Macrophages - Answers✔B) B cells/ Helper T Cell
Which of the following DOES NOT apply to attenuated vaccines?
A) Attenuated vaccines require multiple doses because they possess few antigenic determinants
1
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B) Attenuated vaccines grow and cause mild infections
C) Attenuated vaccines provide herd immunity
D) Attenuated vaccines should not be given to pregnant women - Answers✔A) Attenuated
vaccines require multiple doses because they possess few antigenic determinants
Bacteria food poisoning(intoxication)
A) Has shorter incubation period than bacterial infections.
B) is the result of ingestion of pre-formed toxins already present in food.
C) Is the result of ingestion of bacterial endospores already present in food
A and B
B and C - Answers✔A and B
Which of the following would be the most effective against intracellular pathogens?
A. Cell-mediated immunity (CMI)
B. Complement fixation via alternate pathway
C. Complement fixation via classical pathway
D. Antibody-mediated immunity (AMI) - Answers✔A. Cell-mediated immunity (CMI)
Which of the following classes of antibodies does NOT match with its function?
A. All of them match
B. IgE→ involved in allergic reactions
C. IgG→ major circulating antibody
D. IgA→ major antibody in secretions - Answers✔A. All of them match
Regular injection of allergen over a period of time helps patient overcome severe allergic
reactions. This is known as desensitization. Desensitization involves the gradual drop in IgE and
rise of IgG titer in serum.
A. True
B. False - Answers✔A. True
ELISA is an immunological test that can do all of the these except:
A. Measure the amount (liter) of HIV in a blood sample
B. ELISA can do ALL of these
2
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C. Detect if someone has produced antibody in response to HIV infection
D. Detect if someone is infected with HIV - Answers✔B. ELISA can do ALL of these
When one compares the antibody mediated immunity (AMI) and Cell mediated immunity
(CMI), one notices all of the following except:
A. All of these statements apply
B. Both AMI and CMI are components of the specific immunity
C. Both involved memory cells (Antibody has it, cell does have it I think)
D. CMI is involved in killing cancer and tumor cells
E. Only AMI is involved in classical pathway for complement fixation - Answers✔E. Only AMI
is involved in classical pathway for complement fixation
Graft vs host disease occurs when graft cells attack the recipient tissue. Which of the following
statements apply to it?
A. Disease occurs when MHC I on donor tissue does not match with MHC I on recipient tissue
B. Both are true
C. Disease occurs following bone marrow transplant
D. Neither are true - Answers✔B. Both are true
Immune complex is formed when antigen and antibody bind. Formation of this complex result in
all of the following except:
A) All of these are the consequences of formation of the antigen-antibody complex
B) Complement fixation via classical pathway
C) Opsonization and marking bacteria for destruction
D) Immobilizing bacterial cells via agglutination
E) Inactivation of virus and prevents its attachment to the host cell - Answers✔A) All of these
are the consequences of formation of the antigen-antibody complex
Which of the following is not true?
A) Both Cytotoxic T cells and NK cells can kill cancer cells
B) Acquired (Secondary) immune deficiency is the result of genetic or developmental defects
C) Adaptive, acquired, and specific immunity all refer to the same thing
3
, ©FYNDLAY
D) Antibodies can bind to the surface of bacteria, but they cannot directly lyse them -
Answers✔B) Acquired (Secondary) immune deficiency is the result of genetic or developmental
defects
Which of the following statements are true of igG?
A) Every IgG must have two identical Fab fragments and one Fc fragment
B) None of these statements are true of IgG
C) Fab fragments bind to the antigen
D) Both of these statements are true of IgG - Answers✔D) Both of these statements are true of
IgG
Interferons are types of cytokines that are primarily produced in response to:
A. Fungal infection
B. Viral infection
C. Bacterial infection
D. Protozoan infection - Answers✔B. Viral infection
Which of the following is a MISMATCH?
A. Fever=second line of defense
B. Lymphocytes=third line of defense
C. Phagocytosis=second line of defense
D. Mucous membranes=first line of defense
E. Inflammation=first line of defense - Answers✔E. Inflammation=first line of defense
Which of the following statements is FALSE?
A. In addition to being phagocytic, Macrophages are also antigen presenting cells
B. Both basophils and neutrophils are phagocytic cells
C. Macrophage can directly bind to bacteria and engulf them without the help of either humoral
immunity or complement system components
D. All of the above are TRUE - Answers✔B. Both basophils and neutrophils are phagocytic cells
Major histocompatibility complex molecules such as MHCI are surface proteins that identify self
from nonself. Class I MHC (MHCl) molecules are found in ALL
A. Human cells
4
MCB5252 Exam#2 Practice Questions And
Answers.
Which of the following is not true?
A) Both Cytotoxic T cells and NK cells can kill cancer cells
B) Acquired (Secondary) immune deficiency is the result of genetic or developmental defects
C) Adaptive, acquired, and specific immunity all refer to the same thing
D) Antibodies can bind to the surface of bacteria, but they cannot directly lyse them -
Answers✔B) Acquired (Secondary) immune deficiency is the result of genetic or developmental
defects
Which of the following is NOT TRUE of antigens?
A) Haptens become antigenic if they bind to larger carrier molecules
B) Antigens have size restriction and should be large enough for the immune system to detect
them
C) Polysaccharides are the most antigenic of all polymers
D) Antigens could be found on the surface of bacteria - Answers✔C) Polysaccharides are the
most antigenic of all polymers
Antigens presenting cells (APC's) process by__cells, and present antigens to__cells.
A) Macrophage/Neutrophilis
B) B cells/ Helper T Cell
C) Helper T cells/ plasma cell
D) Cytotoxic T Cells/ Macrophages - Answers✔B) B cells/ Helper T Cell
Which of the following DOES NOT apply to attenuated vaccines?
A) Attenuated vaccines require multiple doses because they possess few antigenic determinants
1
, ©FYNDLAY
B) Attenuated vaccines grow and cause mild infections
C) Attenuated vaccines provide herd immunity
D) Attenuated vaccines should not be given to pregnant women - Answers✔A) Attenuated
vaccines require multiple doses because they possess few antigenic determinants
Bacteria food poisoning(intoxication)
A) Has shorter incubation period than bacterial infections.
B) is the result of ingestion of pre-formed toxins already present in food.
C) Is the result of ingestion of bacterial endospores already present in food
A and B
B and C - Answers✔A and B
Which of the following would be the most effective against intracellular pathogens?
A. Cell-mediated immunity (CMI)
B. Complement fixation via alternate pathway
C. Complement fixation via classical pathway
D. Antibody-mediated immunity (AMI) - Answers✔A. Cell-mediated immunity (CMI)
Which of the following classes of antibodies does NOT match with its function?
A. All of them match
B. IgE→ involved in allergic reactions
C. IgG→ major circulating antibody
D. IgA→ major antibody in secretions - Answers✔A. All of them match
Regular injection of allergen over a period of time helps patient overcome severe allergic
reactions. This is known as desensitization. Desensitization involves the gradual drop in IgE and
rise of IgG titer in serum.
A. True
B. False - Answers✔A. True
ELISA is an immunological test that can do all of the these except:
A. Measure the amount (liter) of HIV in a blood sample
B. ELISA can do ALL of these
2
, ©FYNDLAY
C. Detect if someone has produced antibody in response to HIV infection
D. Detect if someone is infected with HIV - Answers✔B. ELISA can do ALL of these
When one compares the antibody mediated immunity (AMI) and Cell mediated immunity
(CMI), one notices all of the following except:
A. All of these statements apply
B. Both AMI and CMI are components of the specific immunity
C. Both involved memory cells (Antibody has it, cell does have it I think)
D. CMI is involved in killing cancer and tumor cells
E. Only AMI is involved in classical pathway for complement fixation - Answers✔E. Only AMI
is involved in classical pathway for complement fixation
Graft vs host disease occurs when graft cells attack the recipient tissue. Which of the following
statements apply to it?
A. Disease occurs when MHC I on donor tissue does not match with MHC I on recipient tissue
B. Both are true
C. Disease occurs following bone marrow transplant
D. Neither are true - Answers✔B. Both are true
Immune complex is formed when antigen and antibody bind. Formation of this complex result in
all of the following except:
A) All of these are the consequences of formation of the antigen-antibody complex
B) Complement fixation via classical pathway
C) Opsonization and marking bacteria for destruction
D) Immobilizing bacterial cells via agglutination
E) Inactivation of virus and prevents its attachment to the host cell - Answers✔A) All of these
are the consequences of formation of the antigen-antibody complex
Which of the following is not true?
A) Both Cytotoxic T cells and NK cells can kill cancer cells
B) Acquired (Secondary) immune deficiency is the result of genetic or developmental defects
C) Adaptive, acquired, and specific immunity all refer to the same thing
3
, ©FYNDLAY
D) Antibodies can bind to the surface of bacteria, but they cannot directly lyse them -
Answers✔B) Acquired (Secondary) immune deficiency is the result of genetic or developmental
defects
Which of the following statements are true of igG?
A) Every IgG must have two identical Fab fragments and one Fc fragment
B) None of these statements are true of IgG
C) Fab fragments bind to the antigen
D) Both of these statements are true of IgG - Answers✔D) Both of these statements are true of
IgG
Interferons are types of cytokines that are primarily produced in response to:
A. Fungal infection
B. Viral infection
C. Bacterial infection
D. Protozoan infection - Answers✔B. Viral infection
Which of the following is a MISMATCH?
A. Fever=second line of defense
B. Lymphocytes=third line of defense
C. Phagocytosis=second line of defense
D. Mucous membranes=first line of defense
E. Inflammation=first line of defense - Answers✔E. Inflammation=first line of defense
Which of the following statements is FALSE?
A. In addition to being phagocytic, Macrophages are also antigen presenting cells
B. Both basophils and neutrophils are phagocytic cells
C. Macrophage can directly bind to bacteria and engulf them without the help of either humoral
immunity or complement system components
D. All of the above are TRUE - Answers✔B. Both basophils and neutrophils are phagocytic cells
Major histocompatibility complex molecules such as MHCI are surface proteins that identify self
from nonself. Class I MHC (MHCl) molecules are found in ALL
A. Human cells
4
