Pharmacotherapeutics for Advanced Practice-
f f f
A Practical Approach 5th Edition Arcangelo Test Bank LA
f f f f f f f f f
TEST
Nursefpractitionerfprescriptivefauthorityfisfregulatedfby:
1.fThefNationalfCouncilfoffStatefBoardsfoffNursing
2.fThefU.S.fDrugfEnforcementfAdministration
3.fThefStatefBoardfoffNursingfforfeachfstate
4.fThefStatefBoardfoffPharmacyf-fANSWER3.fThefStatefBoardfoffNursingfforfeachfstate
ThefbenefitsftofthefpatientfoffhavingfanfAdvancedfPracticefRegisteredfNursef(APRN)fpre
scriberfinclude:
1.fNursesfknowfmorefaboutfPharmacologyfthanfotherfprescribersfbecauseftheyftakefitfbo
thfinftheirfbasicfnursingfprogramfandfinftheirfAPRNfprogram.
2.fNursesfcarefforfthefpatientffromfafholisticfapproachfandfincludefthefpatientfinfdecisionf
makingfregardingftheirfcare.
3.fAPRNsfareflessflikelyftofprescribefnarcoticsfandfotherfcontrolledfsubstances.
4.fAPRNsfarefableftofprescribefindependentlyfinfallfstates,fwhereasfafphysician'sfassista
ntfneedsftofhavefafphysicianfsupervisingftheirfpractice.f-
fANSWER2.f Nursesf carefforfthefpatientffromfafholisticfapproachfandf includefthef patientf inf
decisionfmakingfregardingftheirfcare.
Clinicalfjudgmentfinfprescribingfincludes:
1.fFactoringfinfthefcostftofthefpatientfoffthefmedicationfprescribed
2.fAlwaysfprescribingfthefnewestfmedicationfavailablefforfthefdiseasefprocess
3.fHandingfoutfdrugfsamplesftofpoorfpatients
4.fPrescribingfallfgenericfmedicationsftofcutfcostsf-
fANSWER1.f Factoringf inf thef costf tof thefpatientfoff thefmedicationfprescribed
Criteriafforfchoosingfanfeffectivefdrugfforfafdisorderfinclude:
,1.fAskingfthefpatientfwhatfdrugftheyfthinkfwouldfworkfbestfforfthem
2.fConsultingfnationallyfrecognizedfguidelinesfforfdiseasefmanagement
3.fPrescribingfmedicationsfthatfarefavailablefasfsamplesfbeforefwritingfafprescription
4.fFollowingfU.S.fDrugfEnforcementfAdministrationfguidelinesfforfprescribingf-
fANSWER2.f Consultingfnationallyf recognizedf guidelinesfforfdiseasefmanagement
Nursefpractitionerfpracticefmayfthrivefunderfhealth-carefreformfbecausefof:
1.fThefdemonstratedfabilityfoffnursefpractitionersftofcontrolfcostsfandfimprovefpatientfout
comes
2.fTheffactfthatfnursefpractitionersfwillfbefableftofpracticefindependently
3.fTheffactfthatfnursefpractitionersfwillfhaveffullfreimbursementfunderfhealth-carefreform
4.fThefabilityftofshiftfaccountabilityfforfMedicaidftofthefstateflevelf-
fANSWER1.fThefdemonstratedf abilityf offnursefpractitionersf tofcontrolf costsf andf improvef
patientfoutcomes
Afpatient'sfnutritionalfintakefandflaboratoryfresultsfreflectfhypoalbuminemia.fThis
isfcriticalftofprescribingfbecause:
1.fDistributionfoffdrugsftoftargetftissuefmayfbefaffected.
2.fThefsolubilityfoffthefdrugfwillfnotfmatchfthefsitefoffabsorption.
3.fTherefwillfbeflessffreefdrugfavailableftofgeneratefanfeffect.
4.fDrugsfboundftofalbuminfarefreadilyfexcretedfbyfthefkidneys.f-
fANSWER1.f Distributionf offdrugsf tof targetf tissuef mayfbefaffected.
Drugsfthatfhavefafsignificantffirst-passfeffect:
1.fMustfbefgivenfbyfthefenteralf(oral)froutefonly
2.fBypassfthefhepaticfcirculation
3.fArefrapidlyfmetabolizedfbyfthefliverfandfmayfhaveflittlefiffanyfdesiredfaction
4.fArefconvertedfbyfthefliverftofmorefactivefandffat-solublefformsf-
fANSWER3.fAref rapidlyfmetabolizedfbyf thef liverfandfmayf havef littlef iffanyfdesiredfaction
Thefroutefoffexcretionfoffafvolatilefdrugfwillflikelyfbefthe:
1.fKidneys
2.fLungs
,3.fBilefandffeces
4.fSkinf-fANSWER2.fLungs
Medroxyprogesteronef(DepofProvera)fisfprescribedfintramuscularlyf(IM)ftofcreatefafstor
agefreservoirfoffthefdrug.fStoragefreservoirs:
1.fAssurefthatfthefdrugfwillfreachfitsfintendedftargetftissue
2.fArefthefreasonfforfgivingfloadingfdoses
3.fIncreaseftheflengthfofftimefafdrugfisfavailablefandfactive
4.fArefmostfcommonfinfcollagenftissuesf-
fANSWER3.fIncreasefthef lengthfoff timefafdrugf isfavailablef andfactive
ThefNPfchoosesftofgivefcephalexinfeveryf8fhoursfbasedfonfknowledgefoffthefdrug's:
1.fPropensityftofgoftoftheftargetfreceptor
2.fBiologicalfhalf-life
3.fPharmacodynamics
4.fSafetyfandfsidefeffectsf-fANSWER2.fBiologicalfhalf-life
Azithromycinfdosingfrequiresfthatftheffirstfday'sfdosagefbeftwicefthosefoffthefother
4fdaysfoffthefprescription.fThisfisfconsideredfafloadingfdose.fAfloadingfdose:
1.fRapidlyfachievesfdrugflevelsfinftheftherapeuticfrange
2.fRequiresffour-ftoffive-half-livesftofattain
3.fIsfinfluencedfbyfrenalffunction
4.fIsfdirectlyfrelatedftofthefdrugfcirculatingftoftheftargetftissuesf-
fANSWER1.f Rapidlyfachievesfdrugf levelsf inftheftherapeuticf range
Thefpointfinftimefonfthefdrugfconcentrationfcurvefthatfindicatesftheffirstfsignfoffa
therapeuticfeffectfisfthe:
1.fMinimumfadversefeffectflevel
2.fPeakfoffaction
3.fOnsetfoffaction
, 4.fTherapeuticfrangef-fANSWER3.fOnsetfoffaction
Phenytoinfrequiresfthatfaftroughflevelfbefdrawn.fPeakfandftroughflevelsfarefdone:
1.fWhenfthefdrugfhasfafwideftherapeuticfrange
2.fWhenfthefdrugfwillfbefadministeredfforfafshortftimefonly
3.fWhenftherefisfafhighfcorrelationfbetweenfthefdosefandfsaturationfoffreceptorfsites
4.fTofdeterminefiffafdrugfisfinftheftherapeuticfrangef-
fANSWER4.fTofdeterminef iffafdrugf isf inftheftherapeuticf range
Aflaboratoryfresultfindicatesfthatfthefpeakflevelfforfafdrugfisfabovefthefminimum
toxicfconcentration.fThisfmeansfthatfthe:
1.fConcentrationfwillfproduceftherapeuticfeffects
2.fConcentrationfwillfproducefanfadversefresponse
3.fTimefbetweenfdosesfmustfbefshortened
4.fDurationfoffactionfoffthefdrugfisftooflongf-
fANSWER2.f Concentrationf willf producefanf adversef response
Drugsfthatfarefreceptorfagonistsfmayfdemonstratefwhatfproperty?
1.fIrreversiblefbindingftofthefdrugfreceptorfsite
2.fUpregulationfwithfchronicfuse
3.fDesensitizationforfdownregulationfwithfcontinuousfuse
4.fInversefrelationshipfbetweenfdrugfconcentrationfandfdrugfactionf-
fANSWER3.f Desensitizationforf downregulationfwithf continuousfuse
Drugsfthatfarefreceptorfantagonists,fsuchfasfbetafblockers,fmayfcause:
1.fDownregulationfoffthefdrugfreceptor
2.fAnfexaggeratedfresponsefiffabruptlyfdiscontinued
3.fPartialfblockadefoffthefeffectsfoffagonistfdrugs
4.fAnfexaggeratedfresponseftofcompetitivefdrugfagonistsf-
fANSWER2.fAnfexaggeratedf responsef iffabruptlyf discontinued
Factorsfthatfaffectfgastricfdrugfabsorptionfinclude:
f f f
A Practical Approach 5th Edition Arcangelo Test Bank LA
f f f f f f f f f
TEST
Nursefpractitionerfprescriptivefauthorityfisfregulatedfby:
1.fThefNationalfCouncilfoffStatefBoardsfoffNursing
2.fThefU.S.fDrugfEnforcementfAdministration
3.fThefStatefBoardfoffNursingfforfeachfstate
4.fThefStatefBoardfoffPharmacyf-fANSWER3.fThefStatefBoardfoffNursingfforfeachfstate
ThefbenefitsftofthefpatientfoffhavingfanfAdvancedfPracticefRegisteredfNursef(APRN)fpre
scriberfinclude:
1.fNursesfknowfmorefaboutfPharmacologyfthanfotherfprescribersfbecauseftheyftakefitfbo
thfinftheirfbasicfnursingfprogramfandfinftheirfAPRNfprogram.
2.fNursesfcarefforfthefpatientffromfafholisticfapproachfandfincludefthefpatientfinfdecisionf
makingfregardingftheirfcare.
3.fAPRNsfareflessflikelyftofprescribefnarcoticsfandfotherfcontrolledfsubstances.
4.fAPRNsfarefableftofprescribefindependentlyfinfallfstates,fwhereasfafphysician'sfassista
ntfneedsftofhavefafphysicianfsupervisingftheirfpractice.f-
fANSWER2.f Nursesf carefforfthefpatientffromfafholisticfapproachfandf includefthef patientf inf
decisionfmakingfregardingftheirfcare.
Clinicalfjudgmentfinfprescribingfincludes:
1.fFactoringfinfthefcostftofthefpatientfoffthefmedicationfprescribed
2.fAlwaysfprescribingfthefnewestfmedicationfavailablefforfthefdiseasefprocess
3.fHandingfoutfdrugfsamplesftofpoorfpatients
4.fPrescribingfallfgenericfmedicationsftofcutfcostsf-
fANSWER1.f Factoringf inf thef costf tof thefpatientfoff thefmedicationfprescribed
Criteriafforfchoosingfanfeffectivefdrugfforfafdisorderfinclude:
,1.fAskingfthefpatientfwhatfdrugftheyfthinkfwouldfworkfbestfforfthem
2.fConsultingfnationallyfrecognizedfguidelinesfforfdiseasefmanagement
3.fPrescribingfmedicationsfthatfarefavailablefasfsamplesfbeforefwritingfafprescription
4.fFollowingfU.S.fDrugfEnforcementfAdministrationfguidelinesfforfprescribingf-
fANSWER2.f Consultingfnationallyf recognizedf guidelinesfforfdiseasefmanagement
Nursefpractitionerfpracticefmayfthrivefunderfhealth-carefreformfbecausefof:
1.fThefdemonstratedfabilityfoffnursefpractitionersftofcontrolfcostsfandfimprovefpatientfout
comes
2.fTheffactfthatfnursefpractitionersfwillfbefableftofpracticefindependently
3.fTheffactfthatfnursefpractitionersfwillfhaveffullfreimbursementfunderfhealth-carefreform
4.fThefabilityftofshiftfaccountabilityfforfMedicaidftofthefstateflevelf-
fANSWER1.fThefdemonstratedf abilityf offnursefpractitionersf tofcontrolf costsf andf improvef
patientfoutcomes
Afpatient'sfnutritionalfintakefandflaboratoryfresultsfreflectfhypoalbuminemia.fThis
isfcriticalftofprescribingfbecause:
1.fDistributionfoffdrugsftoftargetftissuefmayfbefaffected.
2.fThefsolubilityfoffthefdrugfwillfnotfmatchfthefsitefoffabsorption.
3.fTherefwillfbeflessffreefdrugfavailableftofgeneratefanfeffect.
4.fDrugsfboundftofalbuminfarefreadilyfexcretedfbyfthefkidneys.f-
fANSWER1.f Distributionf offdrugsf tof targetf tissuef mayfbefaffected.
Drugsfthatfhavefafsignificantffirst-passfeffect:
1.fMustfbefgivenfbyfthefenteralf(oral)froutefonly
2.fBypassfthefhepaticfcirculation
3.fArefrapidlyfmetabolizedfbyfthefliverfandfmayfhaveflittlefiffanyfdesiredfaction
4.fArefconvertedfbyfthefliverftofmorefactivefandffat-solublefformsf-
fANSWER3.fAref rapidlyfmetabolizedfbyf thef liverfandfmayf havef littlef iffanyfdesiredfaction
Thefroutefoffexcretionfoffafvolatilefdrugfwillflikelyfbefthe:
1.fKidneys
2.fLungs
,3.fBilefandffeces
4.fSkinf-fANSWER2.fLungs
Medroxyprogesteronef(DepofProvera)fisfprescribedfintramuscularlyf(IM)ftofcreatefafstor
agefreservoirfoffthefdrug.fStoragefreservoirs:
1.fAssurefthatfthefdrugfwillfreachfitsfintendedftargetftissue
2.fArefthefreasonfforfgivingfloadingfdoses
3.fIncreaseftheflengthfofftimefafdrugfisfavailablefandfactive
4.fArefmostfcommonfinfcollagenftissuesf-
fANSWER3.fIncreasefthef lengthfoff timefafdrugf isfavailablef andfactive
ThefNPfchoosesftofgivefcephalexinfeveryf8fhoursfbasedfonfknowledgefoffthefdrug's:
1.fPropensityftofgoftoftheftargetfreceptor
2.fBiologicalfhalf-life
3.fPharmacodynamics
4.fSafetyfandfsidefeffectsf-fANSWER2.fBiologicalfhalf-life
Azithromycinfdosingfrequiresfthatftheffirstfday'sfdosagefbeftwicefthosefoffthefother
4fdaysfoffthefprescription.fThisfisfconsideredfafloadingfdose.fAfloadingfdose:
1.fRapidlyfachievesfdrugflevelsfinftheftherapeuticfrange
2.fRequiresffour-ftoffive-half-livesftofattain
3.fIsfinfluencedfbyfrenalffunction
4.fIsfdirectlyfrelatedftofthefdrugfcirculatingftoftheftargetftissuesf-
fANSWER1.f Rapidlyfachievesfdrugf levelsf inftheftherapeuticf range
Thefpointfinftimefonfthefdrugfconcentrationfcurvefthatfindicatesftheffirstfsignfoffa
therapeuticfeffectfisfthe:
1.fMinimumfadversefeffectflevel
2.fPeakfoffaction
3.fOnsetfoffaction
, 4.fTherapeuticfrangef-fANSWER3.fOnsetfoffaction
Phenytoinfrequiresfthatfaftroughflevelfbefdrawn.fPeakfandftroughflevelsfarefdone:
1.fWhenfthefdrugfhasfafwideftherapeuticfrange
2.fWhenfthefdrugfwillfbefadministeredfforfafshortftimefonly
3.fWhenftherefisfafhighfcorrelationfbetweenfthefdosefandfsaturationfoffreceptorfsites
4.fTofdeterminefiffafdrugfisfinftheftherapeuticfrangef-
fANSWER4.fTofdeterminef iffafdrugf isf inftheftherapeuticf range
Aflaboratoryfresultfindicatesfthatfthefpeakflevelfforfafdrugfisfabovefthefminimum
toxicfconcentration.fThisfmeansfthatfthe:
1.fConcentrationfwillfproduceftherapeuticfeffects
2.fConcentrationfwillfproducefanfadversefresponse
3.fTimefbetweenfdosesfmustfbefshortened
4.fDurationfoffactionfoffthefdrugfisftooflongf-
fANSWER2.f Concentrationf willf producefanf adversef response
Drugsfthatfarefreceptorfagonistsfmayfdemonstratefwhatfproperty?
1.fIrreversiblefbindingftofthefdrugfreceptorfsite
2.fUpregulationfwithfchronicfuse
3.fDesensitizationforfdownregulationfwithfcontinuousfuse
4.fInversefrelationshipfbetweenfdrugfconcentrationfandfdrugfactionf-
fANSWER3.f Desensitizationforf downregulationfwithf continuousfuse
Drugsfthatfarefreceptorfantagonists,fsuchfasfbetafblockers,fmayfcause:
1.fDownregulationfoffthefdrugfreceptor
2.fAnfexaggeratedfresponsefiffabruptlyfdiscontinued
3.fPartialfblockadefoffthefeffectsfoffagonistfdrugs
4.fAnfexaggeratedfresponseftofcompetitivefdrugfagonistsf-
fANSWER2.fAnfexaggeratedf responsef iffabruptlyf discontinued
Factorsfthatfaffectfgastricfdrugfabsorptionfinclude:
