Immunization Exam Questions and
Complete Solutions Graded A+
1. Which of the following antibody classes is the mediator of allergy and anaphylaxis?
a. IgA
b. IgE
c. IgG
d. IgM - Answer: B
1. Which of the following describes the role of Helper T cells in mounting an immune response to a
vaccine?
a. Directly kills infected cells
b. Present antigen to antibodies
c. Produce cytokines that stimulate B cells to produce antibodies
d. Produce large amounts of antigen specific antibodies - Answer: C
1. Which of the following is an advantage of passive immunity compared to active immunity?
a. Passive immunity develops in response to infection or after giving a vaccine or toxoid
b. Passive immunity is long-lasting
c. Passive immunity doesn't interfere with the development immune responses from live vaccines
d. Passive immunity protects almost immediately - Answer: D
1. Which of the following is NOT an example of active immunity?
a. Administration of a recombinant immunogenic protein
b. Infection with natural disease
c. Administration of high titer immune globulin
d. Administration of a live attenuated viral vaccine - Answer: C
,1. Mary received a blood transfusion following a recent motor vehicle accident. Response to which of
the following vaccines will be most affected by this event?
a. Pneumococcal polysaccharide vaccine (PPSV)
b. Tetanus-diphtheria
c. Measles vaccine
d. Inactivated influence vaccine (IIV) - Answer: C
1. A US born 67-year-old was recently diagnosed with diabetes. His vaccine records indicate that he
received his Tdap, pneumococcal (PPSV23), and influenza vaccines in October 2015. What vaccines
would you recommend for him?
a. Influenza vaccine, PCV13, varicella vaccine, and hepatitis B vaccine series
b. Influenza vaccine, zoster, PCV13, and hepatitis B vaccine series
c. Influenza vaccine and hepatitis B vaccine series
d. Influenza vaccine, zoster vaccine, and hepatitis B vaccine series - Answer: B
1. Which of the following is/are true regarding live attenuated vaccines?
a. The injectable live attenuated vaccines usually product immunity with one dose
b. They are stronger versions of the "wild" virus
c. Live attenuated vaccines generally have milder reactions versus inactivated vaccines
d. All of the above - Answer: A
1. Joe is a 28-year-old accountant who traveled to Bangkok for a two-month visit two years ago. As part
of his preparations for that trip he received a dose of hepatitis A vaccine. He has received only a Tdap
booster for a finger laceration since his return. He is not planning a trip to Beijing and seeks your advice
regarding hepatitis A vaccination. What do you recommend?
a. He should start the hepatitis A series over and receive a dose now and another dose in 6 months
b. He should receive a dose of hepatitis A vaccine now to complete the series
c. He should receive a double dose of hepatitis A vaccine prior to his departure
d. He should receive a half dose of hepatitis A vaccine now and another dose in 6 months - Answer: B
1. Which of the following represents a true contraindication to measles vaccine?
, a. History of thrombocytopenia
b. Vaccine candidate's mother is pregnant
c. Vaccine candidate is pregnant
d. Moderate or severe acute illness with or without fever - Answer: C
1. A 26-year-old female received the second dose in her series of varicella vaccine 2 weeks ago. Today
she stepped on a rusty nail while working on her farm. Her last tetanus-diphtheria (Td) dose was 6 years
ago. Which of the following immunization strategies is appropriate?
a. Give DTaP now
b. Give Td in two weeks
c. Give Tdap now
d. No booster is necessary - Answer: C
1. Which of the following is a contraindication to receiving live vaccines?
a. Diabetic patient
b. Chronic liver disease
c. Allergy to penicillin
d. Prednisone 40 mg daily - Answer: D
1. Is the following statement true or false? Increasing the interval between doses of a multi-dose vaccine
doesn't diminish the effectiveness of the vaccine.
a. True
b. False - Answer: A
1. Which of the following is a candidate for the HPV9 vaccine?
a. 27-year-old healthy female
b. 35-year-old healthy male
c. 11-year-old healthy male
d. 27-year-old male on prednisone 10 mg daily - Answer: C
Complete Solutions Graded A+
1. Which of the following antibody classes is the mediator of allergy and anaphylaxis?
a. IgA
b. IgE
c. IgG
d. IgM - Answer: B
1. Which of the following describes the role of Helper T cells in mounting an immune response to a
vaccine?
a. Directly kills infected cells
b. Present antigen to antibodies
c. Produce cytokines that stimulate B cells to produce antibodies
d. Produce large amounts of antigen specific antibodies - Answer: C
1. Which of the following is an advantage of passive immunity compared to active immunity?
a. Passive immunity develops in response to infection or after giving a vaccine or toxoid
b. Passive immunity is long-lasting
c. Passive immunity doesn't interfere with the development immune responses from live vaccines
d. Passive immunity protects almost immediately - Answer: D
1. Which of the following is NOT an example of active immunity?
a. Administration of a recombinant immunogenic protein
b. Infection with natural disease
c. Administration of high titer immune globulin
d. Administration of a live attenuated viral vaccine - Answer: C
,1. Mary received a blood transfusion following a recent motor vehicle accident. Response to which of
the following vaccines will be most affected by this event?
a. Pneumococcal polysaccharide vaccine (PPSV)
b. Tetanus-diphtheria
c. Measles vaccine
d. Inactivated influence vaccine (IIV) - Answer: C
1. A US born 67-year-old was recently diagnosed with diabetes. His vaccine records indicate that he
received his Tdap, pneumococcal (PPSV23), and influenza vaccines in October 2015. What vaccines
would you recommend for him?
a. Influenza vaccine, PCV13, varicella vaccine, and hepatitis B vaccine series
b. Influenza vaccine, zoster, PCV13, and hepatitis B vaccine series
c. Influenza vaccine and hepatitis B vaccine series
d. Influenza vaccine, zoster vaccine, and hepatitis B vaccine series - Answer: B
1. Which of the following is/are true regarding live attenuated vaccines?
a. The injectable live attenuated vaccines usually product immunity with one dose
b. They are stronger versions of the "wild" virus
c. Live attenuated vaccines generally have milder reactions versus inactivated vaccines
d. All of the above - Answer: A
1. Joe is a 28-year-old accountant who traveled to Bangkok for a two-month visit two years ago. As part
of his preparations for that trip he received a dose of hepatitis A vaccine. He has received only a Tdap
booster for a finger laceration since his return. He is not planning a trip to Beijing and seeks your advice
regarding hepatitis A vaccination. What do you recommend?
a. He should start the hepatitis A series over and receive a dose now and another dose in 6 months
b. He should receive a dose of hepatitis A vaccine now to complete the series
c. He should receive a double dose of hepatitis A vaccine prior to his departure
d. He should receive a half dose of hepatitis A vaccine now and another dose in 6 months - Answer: B
1. Which of the following represents a true contraindication to measles vaccine?
, a. History of thrombocytopenia
b. Vaccine candidate's mother is pregnant
c. Vaccine candidate is pregnant
d. Moderate or severe acute illness with or without fever - Answer: C
1. A 26-year-old female received the second dose in her series of varicella vaccine 2 weeks ago. Today
she stepped on a rusty nail while working on her farm. Her last tetanus-diphtheria (Td) dose was 6 years
ago. Which of the following immunization strategies is appropriate?
a. Give DTaP now
b. Give Td in two weeks
c. Give Tdap now
d. No booster is necessary - Answer: C
1. Which of the following is a contraindication to receiving live vaccines?
a. Diabetic patient
b. Chronic liver disease
c. Allergy to penicillin
d. Prednisone 40 mg daily - Answer: D
1. Is the following statement true or false? Increasing the interval between doses of a multi-dose vaccine
doesn't diminish the effectiveness of the vaccine.
a. True
b. False - Answer: A
1. Which of the following is a candidate for the HPV9 vaccine?
a. 27-year-old healthy female
b. 35-year-old healthy male
c. 11-year-old healthy male
d. 27-year-old male on prednisone 10 mg daily - Answer: C
