REAL EXAM QUESTIONS AND 100% CORRECT
DETAILED ANSWERS (USMLE STEP 1) MEDICAL
EXAMINATION
What are the major functions of the D1 receptor? -
ANSWWER-Relaxes renal vascular smooth muscle
What are the major functions of the D2 receptor? -
ANSWWER-Modulates transmitter release,
especially in the brain
What are the major functions of the H1 receptor? -
ANSWWER-Increase nasal and bronchial mucus
,production, increase vascular permeability,
contraction of bronchioles, pruritis, pain
What are the major functions of the H2 receptor? -
ANSWWER-Increase gastric acid secretion
What are the major functions of the V1 receptor? -
ANSWWER-Increase vascular smooth muscle
contraction
What are the major functions of the V2 receptor? -
ANSWWER-Increase H2O permeability and
reabsorption in collecting tubules of kidney (V2 is
found in the "2" kidneys)
Drugs for complex seizure - ANSWWER-
Carbamazepine is 1st choice
-All other epilepsy drugs can be used except for
ethosuxamide and the benzodiazepines
What receptors are associate with Gq? -
ANSWWER-H1, α1, V1, M1, and M3
,What receptors are associated with Gs? -
ANSWWER-H2, B1, B2, V2, D1
What receptors are associated with Gi? -
ANSWWER-M2, α2, D2
What is Stevens-Johnson syndrome and which
epilepsy drugs can cause it? - ANSWWER--SJ
syndrome is a prodrome of malaise and fever
followed by a rapid onset of erythematous/purpuric
macules (oral, ocular, genital). Skin lesions progress
to epidermal necrosis and sloughing
-Drugs that can cause this horrific motha ****a:
lamotragine, carbamazepine, phenytoin,
ethosuximide (Stephen Johnson's LAMe CAR SUX
PHENis)
Drugs for simple seizure - ANSWWER--
Carbamazepine is 1st choice
-All other epilepsy drugs can be used except for
ethosuxamide and the benzodiazepines
, Drugs for tonic-clonic seizure - ANSWWER-
Carbamazepine, valproate, and phenytoin are 1st
choice
-Phenobarbital, lamotragine, topiramate, and
levetiracetam can all be used 2nd line
Drugs for absence seizures - ANSWWER-
Ethosuxamide is 1st line
-Lamotragine and valproate may also be used
Drugs for status epilepticus - ANSWWER-
Benzodiazepines (diazepam, lorazepam) are first
line for acute
-Phenytoin is first line prophylaxis
Barbiturates (drugs, mechanism, use, toxicity) -
ANSWWER-Phenobarbital, pentobarbital, thiopental,
secobarbital