NR566 Final (Advanced Pharmacology for
Care of the Family) Questions & 100%
Correct Answers- Latest Test | Graded A+ |
Passed
Anti-Androgens
✓ -:- Finasteride (Propecia)
Leuprolide (Eligard, Lupron, Lupron Depot)
Spironolactone (Aldactone)
Finasteride (Propecia, Proscar)
✓ -:- blocks conversion of testosterone to dihydrotesterone
Used to tx:
-BPH
-male pattern baldness
3 months of therapy need to see benefits
Stopping, reverses effect w/in 12 months
Adverse side effects:
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- Decreased libido
-Impotence
dutasteride (Avodart)
✓ -:- 5-alpha reductase inhibitor
used to tx:
BPH
Can stay in serum up to 6 mon after discontinuing
can be absorbed through skin
pregnant woman shouldn't handle capsules
(fetal anomaly in male fetus)
Adverse Effects
decreased libido
Impotence
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Leuprolide Acetate (Lupron)
✓ -:- Luteinizing hormone - releasing agonist
create reversible:
-orchiectomy state
-oophorectomy state
Used to tx:
- advanced prostatic cancer
- Management of endometriosis
- Uterine fibroids
- polycystic ovarian disease
- central precocious puberty in peds
Flutamide (Eulexin, Euflex)
✓ -:- Truly non-steroidal agent
Used to tx:
-Advanced prostate cancer
-female androgen excess syndrome
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Adverse Effects in males
- gynecomastia
-reversible liver toxicity
Black Box Warning
-hepatic failure
-hepatic encephalopathy
Basline/monthly liver function test for 1st 4 months
Spironolactone (Aldactone)
✓ -:- aldosterone antagonist
potassium sparing diuretic
used for tx:
-female hirsutism (abnormal growth of hair)
-acne
-relief of PMS/PMDD symptoms (25-50 mg/d)
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