Family Medicine EOR: Hematology (Smarty PANCE) Exam Questions and Answers 100% Correct | Latest Version

Family Medicine EOR: Hematology (Smarty PANCE) Exam Questions and Answers 100% Correct | Latest Version Normal or ↓ MCV, ↓ TIBC, ↑ Ferritin (high iron stores) ↓ serum erythropoietin Anemia of chronic disease The only anemia where all three cell lines are decreased (pancytopenia) ↓ WBC, ↓ RBC, ↓ Platelets - will have normal MCV and ↓ Retic Aplastic anemia ↓ Folate, ↑ MCV (macrocytic anemia) looks like B12 but no neurologic symptoms. Common in alcoholics Folate deficiency After infection or medication in an African American male + Heinz Bodies and Bite Cells on smear. Flare triggers: Fava beans, antimalarials, sulfonamides G6PD deficiency History of jaundice, transfusion, new medication or infection (+) direct coombs test Autoimmune Hemolytic anemia ↓ MCV (microcytic), ↑ TIBC, ↓ Ferritin (low iron stores) ↓ MCH (hypochromic). Associated with pica and nail spooning, target cells Iron deficiency African American, pain, family history of blood disorder. Hemoglobin electrophoresis: Hemoglobin S, Blood smear: Sickled RBCs, howell-Jolly bodies, target cells Sickle cell anemia Microcytic hypochromic, elevated iron. Most severe, Mediterranean descent, failure to thrive. Hemoglobin electrophoresis: Hemoglobin A2 and F. Beta thalassemia major Microcytic hypochromic, elevated iron. Mild anemia, often misdiagnosed as iron deficient. Hemoglobin electrophoresis: Hemoglobin A2 Beta thalassemia trait Chinese and southeast Asians. Hemoglobin electrophoresis: Hemoglobin H (H disease), Hemoglobin Bart's (hydrops fetalis), Hemoglobin A (trait) Alpha thalassemia ↑ MCV (macrocytic anemia), Hypersegmented Neutrophils and normal folate, decreased vibratory and position sense Vitamin B12 deficiency Less than 10% radiolabeled vitamin B12 in urine. Normal results when repeated with administration of intrinsic factor Schilling test for the diagnosis of pernicious anemia (antibody to intrinsic factor) What disorder is a hemoglobin electrophoresis result of "SS" indicative of? Sickle cell disease What disorder is a hemoglobin electrophoresis result of "SA" indicative of? Sickle cell trait What type of anemia are cephalosporins PCN NSAIDS methyldopa associated with? Immune hemolytic anemia Erythropoietin analogs should be suspended once the hemoglobin is >_____? 11 mg/dl Erythropoietin analogs should only be initiated if the hemoglobin is < ____? 10 mg/dl What two types of anemia have macroovalocytes? B12 and folate deficiency Which anemia has a decreased MCV, decreased MCH