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QUALIFICATION PLAN FOR GLUTAMATE DEHYDROGENASE (GLDH) AS A BIOMARKER OF DRUG INDUCED LIVER INJURY IN INDIVIDUALS WITH SKELETAL MUSCLE DEGENERATION HISTORY
- Vak
- Instelling
Background Drug-induced liver injury (DILI) remains the single greatest cause for termination of development of drug candidates and withdrawal of approved drugs from the market (Yuan and Kaplowitz, 2013; Kaplowitz, 2005). Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) ser...
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