Maryville University Pharmacology NURS- 615 Exam 2 with Complete Questions and Answers Graded A+

Maryville University Pharmacology NURS- 615 Exam 2 with Complete Questions and Answers Graded A+ How does carbamazepine work? - Answer ️️ -Works by decreasing nerve impulses that cause seizures and pain How often should carbamazepine lab values be monitored? What labs? - Answer ️️ -CBC q 3-4 months What anti-seizure med auto induces metabolism? - Answer ️️ -Carbamazepine What medication decreases the production of RBCs, WBCs, and platelets? - Answer ️️ -Carbamazepine What is carbamazepine half-life? - Answer ️️ -Single dose: 30 hours Multiple dose: 15 hours What is a great risk of seizure potential while taking anti-seizure medications? - Answer ️️ -Stopping the medication abruptly. What type of medication is topiramate (Topamax)? - Answer ️️ -Anti-seizure med What does topiramate cause? - Answer ️️ -Electrolyte imbalance -- hyperchloremic metabolic acidosis What are adverse effects of topiramate? - Answer ️️ -Weight loss, high temperature, and inability to sweat What medication affects Lamictal? - Answer ️️ -OCPs decrease the effects of this drug, so the dose must be doubled Can valproate (Depakote) be used during pregnancy? - Answer ️️ -It is a known teratogen. If needed, must be used after 1st trimester. What must be ruled out in patients before starting an anti-depressant? - Answer ️️ -hypothyroidism Anti-depressant that is to be used with caution in cardiac patients due to behaving like class 1 anti-arrythmics? - Answer ️️ -TCAs TCA side effects are mainly of what type? - Answer ️️ -Anti-cholinergic What is a first-line antidepressant in children? - Answer ️️ -fluoxetine (Prozac) How do you discontinue an SSRI? - Answer ️️ -Taper by reducing the dose by 50% for 3-4 days When are MAOIs effective? - Answer ️️ -In atypical depression or Parkinson's Why are MAOIs reserved for last line of treatment? - Answer ️️ -Lethal drug interactions and food interactions How long before starting a new antidepressant after MAOIs? - Answer ️️ -At least 2 weeks to clear it from system What are high tyramine foods and when are they contraindicated? - Answer ️️ - Fermented foods; aged cheese, wine alcohol Contraindicated with MAOI use Important drug interaction and side effect with MAOIs? - Answer ️️ -Avoid other serotonin drugs and watch for hypertensive crisis What anti-depressant may have sleep issues if taken at night? - Answer ️️ - fluoxetine (Prozac) (SSRI) How do SSRIs work? - Answer ️️ -They block the reuptake of serotonin at the synaptic cleft so there is more serotonin around How are sexual side effects linked to SSRIs? - Answer ️️ -Sexual side effects may start after 1 month; especially common in Paxil How long does it take for SSRIs to work? - Answer ️️ -2-6 weeks; usually within 4 weeks; some symptoms may improve within 1 to 2 weeks What medication is a seroternergic 5-ht receptor partial agonist (partial alpha 1 receptor agonist)? - Answer ️️ -buspirone (Buspar) What is special about buspirone (Buspar)? - Answer ️️ -It has both anti-anxiety and anti-depressant effects. How is treatment with buspirone (Buspar) usual