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UCL PHOL1001: Topic 7 - Cardiovascular System

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The action potentials in the heart are about 100 times longer than those of skeletal muscle. - ANS True The action potential of skeletal muscle is about 2 ms in duration while the action potentials of the heart cells range from about 150 ms in the cells of the SA node to about 300 ms in a Purkinje fiber. The cells of the sinoatrial node have a steady resting potential of -90 mV. - ANS False The membrane potential of the SA node cells is low, about -60 mV, while that of ventricular cells is about -90 mV. The cardiac action potential is conducted through the myocardium entirely via specialized conducting fibres. - ANS False Although the conduction of the cardiac impulse through the atria occurs preferentially via certain fiber bundles, these cells are normal atrial myocytes. The spread of cardiac excitation is delayed by about 0.1 s at the atrioventricular node. - ANS True The conducting tissue of the heart is composed of specialized cardiac myocytes linked by gap junctions. - ANS True In the ventricles, the specialized conducting cells are the bundle cells and the Purkinje fibers, which transmit their action potentials to ventricular myocytes via gap junctions. The P wave of the ECG reflects atrial contraction. - ANS False The P wave reflects atrial depolarization and precedes atrial contraction. The QRST complex of the ECG reflects the time during which ventricular fibers are depolarised. - ANS True The peak amplitude of the ECG is about 1 mV. - ANS True The T wave reflects the repolarization of the ventricular fibres. - ANS True The P-Q interval is normally about 0.1 s. - ANS True During ventricular diastole the pressure in the left ventricle is close to zero. - ANS True During ventricular systole, the pressure in the left ventricle reaches a maximum of about 16 kPa (120 mmHg) - ANS True During ventricular systole, all the blood in the ventricles is ejected. - ANS False The volume of blood in the ventricles at the end of diastole is about 120 ml. Of this about 70 ml is ejected (the stroke volume). The ratio of the stroke volume to the end-diastolic volume is called the ejection fraction and is usually about 60 per cent at rest. During the initial stage of ventricular contraction the volume of the ventricle does not change. - ANS True The mitral valve closes because the pressure in the left ventricle exceeds that in the left atrium. - ANS True

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UCL PHOL1001: Topic 7 - Cardiovascular
System
The action potentials in the heart are about 100 times longer than those of skeletal muscle. - ANS True



The action potential of skeletal muscle is about 2 ms in duration while the action potentials of the heart
cells range from about 150 ms in the cells of the SA node to about 300 ms in a Purkinje fiber.



The cells of the sinoatrial node have a steady resting potential of -90 mV. - ANS False



The membrane potential of the SA node cells is low, about -60 mV, while that of ventricular cells is
about -90 mV.



The cardiac action potential is conducted through the myocardium entirely via specialized conducting
fibres. - ANS False



Although the conduction of the cardiac impulse through the atria occurs preferentially via certain fiber
bundles, these cells are normal atrial myocytes.



The spread of cardiac excitation is delayed by about 0.1 s at the atrioventricular node. - ANS True



The conducting tissue of the heart is composed of specialized cardiac myocytes linked by gap junctions. -
ANS True



In the ventricles, the specialized conducting cells are the bundle cells and the Purkinje fibers, which
transmit their action potentials to ventricular myocytes via gap junctions.



The P wave of the ECG reflects atrial contraction. - ANS False

, The P wave reflects atrial depolarization and precedes atrial contraction.



The QRST complex of the ECG reflects the time during which ventricular fibers are depolarised. - ANS
True



The peak amplitude of the ECG is about 1 mV. - ANS True



The T wave reflects the repolarization of the ventricular fibres. - ANS True



The P-Q interval is normally about 0.1 s. - ANS True



During ventricular diastole the pressure in the left ventricle is close to zero. - ANS True



During ventricular systole, the pressure in the left ventricle reaches a maximum of about 16 kPa (120
mmHg) - ANS True



During ventricular systole, all the blood in the ventricles is ejected. - ANS False



The volume of blood in the ventricles at the end of diastole is about 120 ml. Of this about 70 ml is
ejected (the stroke volume). The ratio of the stroke volume to the end-diastolic volume is called the
ejection fraction and is usually about 60 per cent at rest.



During the initial stage of ventricular contraction the volume of the ventricle does not change. - ANS
True



The mitral valve closes because the pressure in the left ventricle exceeds that in the left atrium. - ANS
True

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