NR546 / NR 546 Midterm Exam (New!! 2024 / 2025 Update): Advanced Pharmacology Psychopharmacology for the Psychiatric-Mental Health Nurse Practitioner | Questions and Verified Answers - Chamberlain

Midterm Exam: NR546 / NR 546 Advanced Pharmacology Psychopharmacology for the Psychiatric-Mental Health Nurse Practitioner | Questions and Verified Answers | New!! 2024 / 2025 Update – Chamberlain Q: Is nicotine an inducer or an inhibitor of the CYP 1A2 enzyme? Answer: inducer Q: Nicotine is an inducer of the CYP 1A2 enzyme. Does the PMHNP anticipate Joshua may need a higher or lower dose of olanzapine to achieve a therapeutic response? Answer: Higher -Nicotine is an inducer of the CYP 1A2 enzyme, so it lowers the concentration of drugs. Therefore, a higher dose of olanzapine may be needed to control his symptoms. Q: Ernesto, a 60-year-old, presents to the PMHNP with report of having anxiety, frequent occurrences of feeling frozen in place and like his heart is pounding out of his chest, as well as having difficulty sleeping. The PMHNP suspects the client has an elevated level of which neurotransmitter? Answer: Norepinephrine -responsible for the regulation of fight or flight responses and can impact mood and sleep. Q: Which of the following is the best medication class for the PMHNP to prescribe for Ernesto to address his elevated norepinephrine levels? Answer: selective serotonin reuptake inhibitor would block the reuptake of serotonin, leaving a larger amount of serotonin available. Increasing the amount of serotonin would help regulate the feelings of fear and anxiety. Reducing the occurrence of fear would help reduce the release of norepinephrine. A serotonin and norepinephrine reuptake inhibitor would prevent the reuptake of norepinephrine, which would not reduce the level of norepinephrine as needed. Benzodiazepines increase the levels of GABA and do not impact norepinephrine. A monoamine oxidase inhibitor would increase levels of norepinephrine. Q: During a follow up appointment after 4 weeks, the PMHNP should assess for the need to add which medication to Ernesto's treatment plan? Answer: The nurse should assess for sexual dysfunction and anticipate the potential need for a phosphodiesterase inhibitor such as sildenafil (Viagra). -After 4 to 6 weeks, the client should be experiencing full effects of the SSRI, so the need for a short-term medication like a benzodiazepine or a beta blocker are not anticipated. St. John's Wort is contraindicated with an SSRI and can cause serotonin syndrome. Q: Glu Answer: Glutamate -amino acid -excitatory neurotransmitter -